tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- Am. J. Physiol. Renal Physiol. (1)
- Drug Metab. Dispos. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Zhao SM et al. | [Long term regulated expansion and committed differentiation of JAK2 gene transfected hematopoietic stem/progenitor cells in vitro]. | 2004 | Zhonghua Xue Ye Xue Za Zhi | pmid:14990041 |
| Xie H et al. | [Effect of FK506 eye-drop combined with keratoplasty on recurrent Mooren's ulcer]. | 2002 | Zhonghua Yan Ke Za Zhi | pmid:11955293 |
| Chen J et al. | [The study of FK506 eye drops preventing and treating immune rejection on limbal allograft transplantation]. | 2003 | Zhonghua Yan Ke Za Zhi | pmid:14766087 |
| Xiang DM et al. | [The observation of tacrolimus eye drops preventing the early immunological rejection after penetrating keratoplasty for fungal keratitis]. | 2017 | Zhonghua Yan Ke Za Zhi | pmid:28412805 |
| Sun YJ et al. | [Systematic review of penetrating keratoplasty rejection treated by immunosuppressants]. | 2010 | Zhonghua Yan Ke Za Zhi | pmid:21211228 |
| Shi WY et al. | [Implantation of FK506 drug delivery system into the anterior chamber for inhibiting corneal rejection in high risk rabbit corneal allograft]. | 2006 | Zhonghua Yan Ke Za Zhi | pmid:16762204 |
| Fei WL et al. | [The pharmacokinetics of FK506 and its nanoparticles in aqueous humor of rabbits]. | 2006 | Zhonghua Yan Ke Za Zhi | pmid:16762205 |
| Lü L et al. | [Experimental studies on the effect of the immunosuppressant FK-506 on penetrating keratoplasty rejection model in rats]. | 1999 | Zhonghua Yan Ke Za Zhi | pmid:11835769 |
| Lü L and Zhang W | [Immunopathologic studies on the effects of immunosuppressant FK 506 on penetrating keratoplasty rejection model in rat]. | 1998 | Zhonghua Yan Ke Za Zhi | pmid:11877144 |
| Jin J et al. | Impact of multidrug resistance 1 gene polymorphism on tacrolimus dose and concentration-to-dose ratio in Chinese liver transplantation recipients. | 2005 | Zhonghua Yi Xue Yi Chuan Xue Za Zhi | pmid:16331555 |