tacrolimus

Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.

Cross Reference

Introduction

To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with tacrolimus?

tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with tacrolimus

MeSH term MeSH ID Detail
Spinal Cord Injuries D013119 34 associated lipids
Burns D002056 34 associated lipids
Cataract D002386 34 associated lipids
Neurotoxicity Syndromes D020258 34 associated lipids
Acne Vulgaris D000152 35 associated lipids
Glomerulonephritis D005921 35 associated lipids
Infarction, Middle Cerebral Artery D020244 35 associated lipids
Fever D005334 35 associated lipids
Heart Failure D006333 36 associated lipids
Nervous System Diseases D009422 37 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with tacrolimus

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with tacrolimus?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with tacrolimus?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with tacrolimus?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with tacrolimus?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with tacrolimus?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with tacrolimus

Download all related citations
Per page 10 20 50 100 | Total 15051
Authors Title Published Journal PubMed Link
Wang C et al. Combining metabolomics and network analysis to improve tacrolimus production in Streptomyces tsukubaensis using different exogenous feedings. 2017 J. Ind. Microbiol. Biotechnol. pmid:28776273
Savaj S et al. Irreversible Lesions of Tacrolimus-induced Posterior Reversible Leukoencephalopathy Syndrome. 2017 Iran J Kidney Dis pmid:29190599
Shahid S et al. Chronic hepatitis in the transplant patient. 2017 Br J Hosp Med (Lond) pmid:28692371
Liao JH et al. Gene Variations of Sixth Complement Component Affecting Tacrolimus Metabolism in Patients with Liver Transplantation for Hepatocellular Carcinoma. 2017 Chin. Med. J. pmid:28685716
Filipec Kanizaj T and Mijic M Inflammatory bowel disease in liver transplanted patients. 2017 World J. Gastroenterol. pmid:28566881
Seo SR et al. Disrupted Skin Barrier is Associated with Burning Sensation after Topical Tacrolimus Application in Atopic Dermatitis. 2017 Acta Derm. Venereol. pmid:28512670
Shen CL et al. Tacrolimus Blood Level Fluctuation Predisposes to Coexisting BK Virus Nephropathy and Acute Allograft Rejection. 2017 Sci Rep pmid:28512328
Egeland EJ et al. High Tacrolimus Clearance Is a Risk Factor for Acute Rejection in the Early Phase After Renal Transplantation. 2017 Transplantation pmid:28452920
Takagi K et al. Syndrome of Inappropriate Antidiuretic Hormone Secretion Following Liver Transplantation. 2017 Acta Med. Okayama pmid:28238015
Sahutoglu T et al. Tac-MMF Versus CsA-MMF/CsA-AZA-Based Regimens in Development of De Novo Complement-Binding Anti-HLA Antibodies After Kidney Transplantation. 2017 Transplant. Proc. pmid:28340811
Rebora A Tacrolimus and oral lichen planus: the question remains. 2017 J Eur Acad Dermatol Venereol pmid:27324047
Størset E et al. The CYP3A biomarker 4β-hydroxycholesterol does not improve tacrolimus dose predictions early after kidney transplantation. 2017 Br J Clin Pharmacol pmid:28146606
Dai Y et al. A case report of coup de sabre patient with hair transplantation. 2017 J Dermatolog Treat pmid:28142293
Hashemizadeh Z et al. Observational Study of Associations between Voriconazole Therapeutic Drug Monitoring, Toxicity, and Outcome in Liver Transplant Patients. 2017 Antimicrob. Agents Chemother. pmid:28923870
Pensi D et al. First UHPLC-MS/MS method coupled with automated online SPE for quantification both of tacrolimus and everolimus in peripheral blood mononuclear cells and its application on samples from co-treated pediatric patients. 2017 J Mass Spectrom pmid:28098395
Hayes W et al. Hypomagnesemia and increased risk of new-onset diabetes mellitus after transplantation in pediatric renal transplant recipients. 2017 Pediatr. Nephrol. pmid:28039534
Wang L et al. Efficacy and safety of tacrolimus for myasthenia gravis: a systematic review and meta-analysis. 2017 J. Neurol. pmid:28921038
Kalt DA Tacrolimus: A Review of Laboratory Detection Methods and Indications for Use. 2017 Lab Med pmid:29096030
Andrews LM et al. Pharmacokinetic considerations related to therapeutic drug monitoring of tacrolimus in kidney transplant patients. 2017 Expert Opin Drug Metab Toxicol pmid:29084469
Vanhove T et al. Pretransplant 4β-hydroxycholesterol does not predict tacrolimus exposure or dose requirements during the first days after kidney transplantation. 2017 Br J Clin Pharmacol pmid:28603840