|
The discovery of FK-506 and U.S. development. |
1991 |
Nephrol News Issues |
pmid:1720512
|
Zheng B et al. |
Effects of the new and highly active immunosuppressant, rapamycin, on lymphoid tissues and cells in vivo. |
1991 |
Transplant. Proc. |
pmid:1703717
|
Mieles L et al. |
Interaction between FK506 and clotrimazole in a liver transplant recipient. |
1991 |
Transplantation |
pmid:1721250
|
Yabuuchi H et al. |
Prominent prolongation of islet xenograft survival in combination therapy with FK 506 and 15-deoxyspergualin. |
1991 |
Transplant. Proc. |
pmid:1703718
|
|
First International Congress on FK 506. August 21-24, 1991, Pittsburgh, PA. |
1991 |
Transplant. Proc. |
pmid:1721253
|
Goto T et al. |
FK 506: historical perspectives. |
1991 |
Transplant. Proc. |
pmid:1721254
|
Farghali H et al. |
Effect of FK 506 chronic administration on bromosulphthalein hepatic excretion in rats. |
1991 |
Transplant. Proc. |
pmid:1721283
|
Farghali H et al. |
A biochemical and 31P-NMR investigation of the effect of FK 506 and cyclosporine pretreatment on immobilized hepatocytes perifused with ethanol. |
1991 |
Transplant. Proc. |
pmid:1721284
|
Farghali H et al. |
FK 506 modulates D-galactosamine-induced hepatitis in rats. |
1991 |
Transplant. Proc. |
pmid:1721285
|
Müller MK et al. |
Inhibition of insulin release by FK 506 and its prevention by rioprostil, a stable prostaglandin E1 analogue. |
1991 |
Transplant. Proc. |
pmid:1721286
|
Matsuura T et al. |
Beneficial immunosuppressive effect of combined use of FK 506 and cyclosporine assessed by proliferative responses of cloned human T cells. |
1991 |
Transplant. Proc. |
pmid:1721316
|
Jiang H et al. |
Combined immunosuppressive effect of FK 506 and other immunosuppressive agents on PHA- and CD3-stimulated human lymphocyte proliferation in vitro. |
1991 |
Transplant. Proc. |
pmid:1721317
|
Yagihashi A et al. |
The effect of FK 506 on peripheral blood T-lymphocyte subsets in orthotopic liver transplant patients. |
1991 |
Transplant. Proc. |
pmid:1721318
|
Woo J et al. |
Effects of FK 506, mycophenolic acid, and bredinin on OKT-3-, PMA-, and alloantigen-induced activation molecule expression on cultured CD4+ and CD8+ human lymphocytes. |
1991 |
Transplant. Proc. |
pmid:1721319
|
Jain AB et al. |
Correlation of rejection episodes with FK 506 dosage, FK 506 level, and steroids following primary orthotopic liver transplant. |
1991 |
Transplant. Proc. |
pmid:1721347
|
Takaya S et al. |
Retransplantation of liver: a comparison of FK 506- and cyclosporine-treated patients. |
1991 |
Transplant. Proc. |
pmid:1721348
|
Morel P et al. |
Liver retransplantation in adults: overall results and determinant factors affecting the outcome. |
1991 |
Transplant. Proc. |
pmid:1721349
|
Felser I et al. |
Changes in quality of life following conversion from CyA to FK 506 in orthotopic liver transplant patients. |
1991 |
Transplant. Proc. |
pmid:1721350
|
Schreiber SL |
Chemistry and biology of the immunophilins and their immunosuppressive ligands. |
1991 |
Science |
pmid:1702904
|
Wagner K et al. |
Effect of FK 506 on excretion of urinary enzymes in rats. |
1991 |
Transplant. Proc. |
pmid:1721379
|
Warty V et al. |
Distribution of FK 506 in plasma lipoproteins in transplant patients. |
1991 |
Transplant. Proc. |
pmid:1703363
|
Prasad SJ et al. |
In vitro effects of cyclosporine and FK 506 on the renal cortex. |
1991 |
Transplant. Proc. |
pmid:1721380
|
Kusne S et al. |
Early infections in kidney transplant recipients under FK 506. |
1991 |
Transplant. Proc. |
pmid:1703364
|
Yamada K et al. |
Short-term FK 506-induced morphological changes in rat kidneys. |
1991 |
Transplant. Proc. |
pmid:1721381
|
Moutabarrik A et al. |
FK 506 mechanism of nephrotoxicity: stimulatory effect on endothelin secretion by cultured kidney cells and tubular cell toxicity in vitro. |
1991 |
Transplant. Proc. |
pmid:1721382
|
Tze WJ et al. |
Long-term survival of islet allografts in diabetic rats treated with FK 506. |
1991 |
Transplant. Proc. |
pmid:1721411
|
Wang X et al. |
Intraportal FK 506 improves intrahepatic islet allograft survival. |
1991 |
Transplant. Proc. |
pmid:1721412
|
Ohtsuka S et al. |
The effect of short-term FK 506 therapy on pancreas transplantation in rats. |
1991 |
Transplant. Proc. |
pmid:1721413
|
de Paulis A et al. |
FK-506, a potent novel inhibitor of the release of proinflammatory mediators from human Fc epsilon RI+ cells. |
1991 |
J. Immunol. |
pmid:1706398
|
Griffiths EJ and Halestrap AP |
Further evidence that cyclosporin A protects mitochondria from calcium overload by inhibiting a matrix peptidyl-prolyl cis-trans isomerase. Implications for the immunosuppressive and toxic effects of cyclosporin. |
1991 |
Biochem. J. |
pmid:1706598
|
Brabletz T et al. |
The immunosuppressives FK 506 and cyclosporin A inhibit the generation of protein factors binding to the two purine boxes of the interleukin 2 enhancer. |
1991 |
Nucleic Acids Res. |
pmid:1707162
|
Yokomise H et al. |
Immunosuppressive effects of FK 506 in canine lung transplantation. |
1991 |
Transplant. Proc. |
pmid:1721442
|
Hasegawa S et al. |
FK 506 and cyclosporine: effects and side effects in canine lung transplantation. |
1991 |
Transplant. Proc. |
pmid:1721443
|
Wada H et al. |
Dose response to FK 506 in canine lung transplantation. |
1991 |
Transplant. Proc. |
pmid:1721444
|
Lin CY et al. |
Effects of FK 506 on the biochemical markers in canine lung allograft rejection. |
1991 |
Transplant. Proc. |
pmid:1721445
|
McAlpine JB et al. |
Revised NMR assignments for rapamycin. |
1991 |
J. Antibiot. |
pmid:1712766
|
Banerji SS et al. |
The immunosuppressant FK-506 specifically inhibits mitogen-induced activation of the interleukin-2 promoter and the isolated enhancer elements NFIL-2A and NF-AT1. |
1991 |
Mol. Cell. Biol. |
pmid:1712901
|
Markus PM et al. |
FK 506 reverses acute graft-versus-host disease after allogeneic bone marrow transplantation in rats. |
1991 |
Surgery |
pmid:1713358
|
Sakai K et al. |
The effect of a new immunosuppressive agent, FK-506, on xenogeneic neural transplantation in rodents. |
1991 |
Brain Res. |
pmid:1723023
|
Forrest MJ et al. |
FK-506 and cyclosporin A: selective inhibition of calcium ionophore-induced polymorphonuclear leukocyte degranulation. |
1991 |
Biochem. Pharmacol. |
pmid:1716098
|
Weaver JL et al. |
Comparison of the in vitro and biophysical effects of cyclosporine A, FK-506, and mycophenolic acid on human peripheral blood lymphocytes. |
1991 |
Immunopharmacol Immunotoxicol |
pmid:1723084
|
DiLella AG and Craig RJ |
Exon organization of the human FKBP-12 gene: correlation with structural and functional protein domains. |
1991 |
Biochemistry |
pmid:1716149
|
Burres NS et al. |
Dunaimycins, a new complex of spiroketal 24-membered macrolides with immunosuppressive activity. III. Immunosuppressive activities of dunaimycins. |
1991 |
J. Antibiot. |
pmid:1723403
|
Nielsen JB et al. |
Biosynthesis of the immunosuppressant immunomycin: the enzymology of pipecolate incorporation. |
1991 |
Biochemistry |
pmid:2043618
|
McKeon F |
When worlds collide: immunosuppressants meet protein phosphatases. |
1991 |
Cell |
pmid:1716181
|
Petros AM et al. |
NMR studies of an FK-506 analogue, [U-13C]ascomycin, bound to FKBP: conformation and regions of ascomycin involved in binding. |
1991 |
J. Med. Chem. |
pmid:1716684
|
Pourtier-Manzanedo A et al. |
FK-506 (fujimycin) reverses the multidrug resistance of tumor cells in vitro. |
1991 |
Anticancer Drugs |
pmid:1724925
|
Nakahama H et al. |
Comparative effects of cyclosporine A and FK-506 on endothelin secretion by a cultured renal cell line, LLC-PK1. |
1991 |
J. Cardiovasc. Pharmacol. |
pmid:1725322
|
Romanowski P et al. |
[Synthetic immunomodulators designed on the basis of natural products of microorganisms]. |
1991 |
Postepy Biochem. |
pmid:1725924
|
Altmeyer A et al. |
Unexpected up-regulation of gene expression by cyclosporin A and FK-506 in a T-cell lymphoma: both immunosuppressants augment Ly-6E antigen induction by interferon-gamma in the presence of ionomycin. |
1991 |
Int. J. Immunopharmacol. |
pmid:1726093
|