MeSH term | MeSH ID | Detail |
---|---|---|
Adenocarcinoma | D000230 | 166 associated lipids |
Lung Neoplasms | D008175 | 171 associated lipids |
Body Weight | D001835 | 333 associated lipids |
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with tacrolimus
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Azuma N et al. | Immunosuppression with FK506 in rat arterial allografts: fate of allogeneic endothelial cells. | 1999 | J. Vasc. Surg. | pmid:10194498 |
Mollison KW et al. | Discovery of ascomycin analogs with potent topical but weak systemic activity for treatment of inflammatory skin diseases. | 1998 | Curr. Pharm. Des. | pmid:10197049 |
De Lima JJ et al. | Effects of FK506 in rat and human resistance arteries. | 1999 | Kidney Int. | pmid:10201018 |
Sloper CM et al. | Tacrolimus (FK506) in the treatment of posterior uveitis refractory to cyclosporine. | 1999 | Ophthalmology | pmid:10201592 |
Nagasaki Y et al. | Reversal of hypopigmentation in phenylketonuria mice by adenovirus-mediated gene transfer. | 1999 | Pediatr. Res. | pmid:10203136 |
Hortelano S et al. | Protective effect of cyclosporin A and FK506 from nitric oxide-dependent apoptosis in activated macrophages. | 1999 | Br. J. Pharmacol. | pmid:10205001 |
Cetinkale O et al. | Modulating the functions of neutrophils and lipid peroxidation by FK506 in a rat model of thermal injury. | 1999 | Burns | pmid:10208383 |
Lütkes P et al. | [Quality of life following transplantation. The impact ofa new immunosuppressive substance]. | 1999 | Zentralbl Chir | pmid:10209841 |
Jani A et al. | Modulation of cell-mediated immunity prolongs adenovirus-mediated transgene expression in sciatic nerve. | 1999 | Hum. Gene Ther. | pmid:10210146 |
Knoll GA and Bell RC | Tacrolimus versus cyclosporin for immunosuppression in renal transplantation: meta-analysis of randomised trials. | 1999 | BMJ | pmid:10213717 |