tacrolimus

Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.

Cross Reference

Introduction

To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with tacrolimus?

tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with tacrolimus

MeSH term MeSH ID Detail
Adenocarcinoma D000230 166 associated lipids
Lung Neoplasms D008175 171 associated lipids
Body Weight D001835 333 associated lipids
Per page 10 20 50 100 | Total 613

PubChem Associated disorders and diseases

What pathways are associated with tacrolimus

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with tacrolimus?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with tacrolimus?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with tacrolimus?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with tacrolimus?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with tacrolimus?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with tacrolimus

Download all related citations
Per page 10 20 50 100 | Total 15051
Authors Title Published Journal PubMed Link
Caraveo G et al. FKBP12 contributes to α-synuclein toxicity by regulating the calcineurin-dependent phosphoproteome. 2017 Proc. Natl. Acad. Sci. U.S.A. pmid:29229832
Al Taii H et al. The use of tacrolimus in refractory autoimmune hepatitis in children and adults: a single center experience. 2017 Scand. J. Gastroenterol. pmid:27633047
Krenzien F et al. Age-Dependent Metabolic and Immunosuppressive Effects of Tacrolimus. 2017 Am. J. Transplant. pmid:27754593
Hurtgen BJ et al. Impairment of early fracture healing by skeletal muscle trauma is restored by FK506. 2017 BMC Musculoskelet Disord pmid:28606129
Trasi NS et al. Evaluation of the Crystallization Tendency of Commercially Available Amorphous Tacrolimus Formulations Exposed to Different Stress Conditions. 2017 Pharm. Res. pmid:28687987
Koo K et al. Beyond monotherapy: a systematic review on creative strategies in topical therapy of psoriasis. 2017 J Dermatolog Treat pmid:28481664
Verga E et al. Stoma Complications: Corticosteroid and Silver Nitrate-Resistant Inflammation Successfully Treated with Topical Tacrolimus. 2017 Dig Surg pmid:28183090
Khimani F et al. Predictors of overall survival among patients treated with sirolimus/tacrolimus vs methotrexate/tacrolimus for GvHD prevention. 2017 Bone Marrow Transplant. pmid:28368376
Wang J et al. Comparative proteomic and metabolomic analysis of Streptomyces tsukubaensis reveals the metabolic mechanism of FK506 overproduction by feeding soybean oil. 2017 Appl. Microbiol. Biotechnol. pmid:28175948
Eshraghian A et al. Post-transplant lymphoproliferative disorder after liver transplantation: Incidence, long-term survival and impact of serum tacrolimus level. 2017 World J. Gastroenterol. pmid:28275302
Ribero S and Borradori L Re: risk of malignancy and systemic absorption after application of topical tacrolimus in oral lichen planus. 2017 J Eur Acad Dermatol Venereol pmid:27291784
Mekaj AY et al. Effects of hyaluronic acid and tacrolimus on the prevention of perineural scar formation and on nerve regeneration after sciatic nerve repair in a rabbit model. 2017 Eur J Trauma Emerg Surg pmid:27194249
Jessop S et al. Drugs for discoid lupus erythematosus. 2017 Cochrane Database Syst Rev pmid:28476075
Kirresh T et al. Development and validation of a liquid chromatography-mass spectrometric assay for simultaneous determination of tacrolimus and 13-O-desmethyl tacrolimus in rat kidney tissue. 2017 J Pharm Biomed Anal pmid:28063333
Krämer BK et al. Efficacy of Prolonged- and Immediate-release Tacrolimus in Kidney Transplantation: A Pooled Analysis of Two Large, Randomized, Controlled Trials. 2017 Transplant. Proc. pmid:29149958
Ianiri G et al. FKBP12-Dependent Inhibition of Calcineurin Mediates Immunosuppressive Antifungal Drug Action in . 2017 MBio pmid:29066552
Flahault A et al. Clinical impact of the CYP3A5 6986A>G allelic variant on kidney transplantation outcomes. 2017 Pharmacogenomics pmid:27977332
Suzuki Y et al. Improved Open-Well Stability of Affinity Column-Mediated Immunoassay Reagent for Determining Blood Tacrolimus. 2017 Ther Drug Monit pmid:28282367
Rivosecchi RM et al. Effects of Isavuconazole on the Plasma Concentrations of Tacrolimus among Solid-Organ Transplant Patients. 2017 Antimicrob. Agents Chemother. pmid:28674051
Krüger-Genge A et al. Effects of Tacrolimus or Sirolimus on the adhesion of vascular wall cells: Controlled in-vitro comparison study. 2017 Clin. Hemorheol. Microcirc. pmid:28869461