tacrolimus

Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.

Cross Reference

Introduction

To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with tacrolimus?

tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with tacrolimus

MeSH term MeSH ID Detail
Adenocarcinoma D000230 166 associated lipids
Lung Neoplasms D008175 171 associated lipids
Body Weight D001835 333 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with tacrolimus

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with tacrolimus?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with tacrolimus?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with tacrolimus?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with tacrolimus?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with tacrolimus?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with tacrolimus

Download all related citations
Per page 10 20 50 100 | Total 15051
Authors Title Published Journal PubMed Link
Xu L et al. Potential for pharmacology of ryanodine receptor/calcium release channels. 1998 Ann. N. Y. Acad. Sci. pmid:10603942
Bers DM et al. Factors that control sarcoplasmic reticulum calcium release in intact ventricular myocytes. 1998 Ann. N. Y. Acad. Sci. pmid:10603944
MacFarlane GD et al. Analysis of whole blood tacrolimus concentrations in liver transplant patients exhibiting impaired liver function. 1999 Ther Drug Monit pmid:10604816
Wright DC et al. A comparison of the sensitivity of pig and human peripheral blood mononuclear cells to the antiproliferative effects of traditional and newer immunosuppressive agents. 1999 Transpl. Immunol. pmid:10608297
Qi Z et al. Malononitrilamides and tacrolimus additively prevent acute rejection in rat cardiac allografts. 1999 Transpl. Immunol. pmid:10608300
Olyaei AJ et al. Immunosuppressant-induced nephropathy: pathophysiology, incidence and management. 1999 Drug Saf pmid:10612271
Freudenberger R et al. Antithrombotic effect of FK506 vs cyclosporine in cardiac transplant recipients: potential implications in transplant arteriopathy. 1999 J. Heart Lung Transplant. pmid:10612383
Yen MT et al. Oscillopsia and pseudonystagmus in kidney transplant patients. 1999 Am. J. Ophthalmol. pmid:10612521
Bitker MO et al. [Combined renal and pancreas transplantation as treatment for chronic renal insufficiency of diabetic origin: a series of 50 consecutive transplantations]. 1999 Chirurgie pmid:10615774
Crétolle-Vastel C et al. [Role of calcineurin-dependent drugs on the immunosuppressive effect induced by the anti-LFA-1 antibody in a fetal intestinal transplantation model in mice]. 1999 Chirurgie pmid:10615777
van Hooff JP and Christiaans MH Use of tacrolimus in renal transplantation. 1999 Transplant. Proc. pmid:10616483
Charco R et al. CD28 regulation in liver transplant recipients treated with two different immunosuppressive regimens. 1999 Transplant. Proc. pmid:10616508
Kindt MV et al. Tacrolimus toxicity in rhesus monkey: model for clinical side effects. 1999 Transplant. Proc. pmid:10616519
Gaston RS Potential utility of rapamycin and tacrolimus in long-term, low-toxicity regimens. 1999 Transplant. Proc. pmid:10616556
Land W Mycophenolate mofetil-based immunosuppressive therapy: induction, maintenance, and conversion protocols in renal transplantation. 1999 Transplant. Proc. pmid:10616558
Hida H et al. Dopa-producing astrocytes generated by adenoviral transduction of human tyrosine hydroxylase gene: in vitro study and transplantation to hemiparkinsonian model rats. 1999 Neurosci. Res. pmid:10616914
Hashii M et al. cADP-ribose potentiates cytosolic Ca2+ elevation and Ca2+ entry via L-type voltage-activated Ca2+ channels in NG108-15 neuronal cells. 2000 Biochem. J. pmid:10620496
Uchino T et al. Effect of FK 506 and lipo prostaglandin E1 on heart allograft survival in rats. 1999 Scand. Cardiovasc. J. pmid:10622549
Patella V et al. HIV-1 gp120 induces IL-4 and IL-13 release from human Fc epsilon RI+ cells through interaction with the VH3 region of IgE. 2000 J. Immunol. pmid:10623799
Mehta P et al. Increased clearance of tacrolimus in children: need for higher doses and earlier initiation prior to bone marrow transplantation. 1999 Bone Marrow Transplant. pmid:10627642