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High Intrapatient Tacrolimus Variability Is Associated With Worse Outcomes in Renal Transplantation Using a Low-Dose Tacrolimus Immunosuppressive Regime. |
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Transplantation |
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Efficacy and Safety of Everolimus and Mycophenolic Acid With Early Tacrolimus Withdrawal After Liver Transplantation: A Multicenter Randomized Trial. |
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Early Conversion From Calcineurin Inhibitor- to Everolimus-Based Therapy Following Kidney Transplantation: Results of the Randomized ELEVATE Trial. |
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2017 |
Int J Clin Pharm |
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Birth defects in juvenile Wistar rats after exposure to immunosuppressive drugs during pregnancy. |
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Histol. Histopathol. |
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Genotype-based tacrolimus dosing guidelines: with or without CYP3A4*22? |
2017 |
Pharmacogenomics |
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Inhibition effect of tacrolimus and platelet-derived growth factor-BB on restenosis after vascular intimal injury. |
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Biomed. Pharmacother. |
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Taste-masked tacrolimus-phospholipid nanodispersions: dissolution enhancement, taste masking and reduced gastric complications. |
2017 |
Pharm Dev Technol |
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Wound Healing Complications in Kidney Transplant Recipients Receiving Everolimus. |
2017 |
Transplantation |
pmid:27490418
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[Study on the Effect of Immunosuppressive Agent FK506 on Growth and Migration of Lung Cancer Cell]. |
2017 |
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Atypical pneumonia due to human bocavirus in an immunocompromised patient. |
2017 |
CMAJ |
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Successful Treatment of Behçet's Disease Associated with Acute Myeloid Leukemia with Myelodysplasia-related Changes Using Azacitidine and Tacrolimus before Allogeneic Hematopoietic Stem Cell Transplantation. |
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Intern. Med. |
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Genotype-guided tacrolimus dosing in African-American kidney transplant recipients. |
2017 |
Pharmacogenomics J. |
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Is trough level variability the new tool for identifying patients at risk for rejection after transplantation? |
2017 |
Nephrol. Dial. Transplant. |
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Undre N and Dickinson J |
Relative bioavailability of single doses of prolonged-release tacrolimus administered as a suspension, orally or via a nasogastric tube, compared with intact capsules: a phase 1 study in healthy participants. |
2017 |
BMJ Open |
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Response to: 'Response to: Bodyweight-adjustments introduce significant correlations between CYP3A metrics and tacrolimus clearance'. |
2017 |
Br J Clin Pharmacol |
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Forns X et al. |
Efficacy, safety, and pharmacokinetics of simeprevir, daclatasvir, and ribavirin in patients with recurrent hepatitis C virus genotype 1b infection after orthotopic liver transplantation: The Phase II SATURN study. |
2017 |
Transpl Infect Dis |
pmid:28295849
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Ericzon BG et al. |
Pharmacokinetics of prolonged-release tacrolimus versus immediate-release tacrolimus in de novo liver transplantation: A randomized phase III substudy. |
2017 |
Clin Transplant |
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Efficacy of Rectal Tacrolimus for Induction Therapy in Patients With Resistant Ulcerative Proctitis. |
2017 |
Clin. Gastroenterol. Hepatol. |
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The onset risk of carcinoma in patients continuing tacrolimus topical treatment for oral lichen planus: a case report. |
2017 |
Odontology |
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Decreased tacrolimus plasma concentrations during HCV therapy: a drug-drug interaction or is there an alternative explanation? |
2017 |
Int. J. Antimicrob. Agents |
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Reduction of FR900525 using an S-(2-aminoethyl) l-cysteine-resistant mutant. |
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J. Biosci. Bioeng. |
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Sakurai K et al. |
Efficacy of combination therapy with tacrolimus and mizoribine for cyclophosphamide-resistant ANCA-associated glomerulonephritis. |
2017 |
Int J Rheum Dis |
pmid:28205382
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A new efficient method of generating photoaffinity beads for drug target identification. |
2017 |
Bioorg. Med. Chem. Lett. |
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Suppressive Effect of 1α,25-Dihydroxyvitamin D3 on Th17-Immune Responses in Kidney Transplant Recipients With Tacrolimus-Based Immunosuppression. |
2017 |
Transplantation |
pmid:28107277
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Wungwattana M and Savic M |
Tacrolimus interaction with nafcillin resulting in significant decreases in tacrolimus concentrations: A case report. |
2017 |
Transpl Infect Dis |
pmid:28067989
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Ak K et al. |
Tacrolimus-Eluting Suture Inhibits Neointimal Hyperplasia: An Experimental In Vivo Study in Rats. |
2017 |
Eur J Vasc Endovasc Surg |
pmid:28065442
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Effects of Cyclosporine, Tacrolimus, and Rapamycin on Osteoblasts. |
2017 |
Transplant. Proc. |
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Clinical Challenges of Tacrolimus for Maintenance Immunosuppression Post-Lung Transplantation. |
2017 |
Transplant. Proc. |
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AS2553627, a novel JAK inhibitor, prevents chronic rejection in rat cardiac allografts. |
2017 |
Eur. J. Pharmacol. |
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Improvement in baroreflex control of renal sympathetic nerve activity in obese Sprague Dawley rats following immunosuppression. |
2017 |
Acta Physiol (Oxf) |
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No evidence for progressive deterioration in stimulated insulin secretion in renal transplant recipients after 12years tacrolimus exposure. |
2017 |
J. Diabetes Complicat. |
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Dual roles of TPGS based microemulsion for tacrolimus: Enhancing the percutaneous delivery and anti-psoriatic efficacy. |
2017 |
Int J Pharm |
pmid:28629978
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Clinical Evaluation of Modified Release and Immediate Release Tacrolimus Formulations. |
2017 |
AAPS J |
pmid:28717926
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Dynamic effects of CYP3A5 polymorphism on dose requirement and trough concentration of tacrolimus in renal transplant recipients. |
2017 |
J Clin Pharm Ther |
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Isoglycyrrhizinate Magnesium Enhances Hepatoprotective Effect of FK506 on Ischemia-Reperfusion Injury Through HMGB1 Inhibition in a Rat Model of Liver Transplantation. |
2017 |
Transplantation |
pmid:28885495
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Burbulla LF et al. |
Dopamine oxidation mediates mitochondrial and lysosomal dysfunction in Parkinson's disease. |
2017 |
Science |
pmid:28882997
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Potential protective effect of Helicobacter pylori on the development of gastrointestinal GvHD. |
2016 |
Bone Marrow Transplant. |
pmid:26950379
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Post-transplantation cyclophosphamide versus conventional graft-versus-host disease prophylaxis in mismatched unrelated donor haematopoietic cell transplantation. |
2016 |
Br. J. Haematol. |
pmid:26947769
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Kiyohara H et al. |
Up-to-date medical treatment for ulcerative colitis. |
2016 |
Nihon Shokakibyo Gakkai Zasshi |
pmid:26947041
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Carcas-Sansuán AJ |
Limited sampling strategies for once daily tacrolimus exposure monitoring. |
2016 |
Eur. J. Clin. Pharmacol. |
pmid:26939899
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Kloster-Jensen K et al. |
Treatment with Tacrolimus and Sirolimus Reveals No Additional Adverse Effects on Human Islets In Vitro Compared to Each Drug Alone but They Are Reduced by Adding Glucocorticoids. |
2016 |
J Diabetes Res |
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Shen X et al. |
Calcineurin inhibitors cyclosporin A and tacrolimus protect against podocyte injury induced by puromycin aminonucleoside in rodent models. |
2016 |
Sci Rep |
pmid:27580845
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Khan S et al. |
Tacrolimus-loaded nanostructured lipid carriers for oral delivery-in vivo bioavailability enhancement. |
2016 |
Eur J Pharm Biopharm |
pmid:27793753
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Influence of tacrolimus metabolism rate on BKV infection after kidney transplantation. |
2016 |
Sci Rep |
pmid:27573493
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Consideration of the ethnic prevalence of genotypes in the clinical use of tacrolimus. |
2016 |
Pharmacogenomics |
pmid:27790923
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Tang J et al. |
Cytokine Profile in Calcineurin Inhibitor-Induced Chronic Nephrotoxicity in Chinese Liver Transplant Recipients. |
2016 |
Transplant. Proc. |
pmid:27788813
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Risk Factors for Subtherapeutic Tacrolimus Levels after Conversion from Continuous Intravenous Infusion to Oral in Children after Allogeneic Hematopoietic Cell Transplantation. |
2016 |
Biol. Blood Marrow Transplant. |
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Impact of Trough Levels of Tacrolimus on Kidney Function and Graft Survival in Short and Longer Periods After Renal Transplantation. |
2016 |
Transplant. Proc. |
pmid:27788794
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Tacrolimus and oral lichen planus. Possible absorption after mucosal application? |
2016 |
J Eur Acad Dermatol Venereol |
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A case of lupus nephritis treated with clarithromycin, tacrolimus, and glucocorticoids. |
2016 |
Kaohsiung J. Med. Sci. |
pmid:27638410
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Paclitaxel and Tacrolimus Coencapsulated Polymeric Micelles That Enhance the Therapeutic Effect of Drug-Resistant Ovarian Cancer. |
2016 |
ACS Appl Mater Interfaces |
pmid:26809267
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Management of sensitized pediatric patients prior to renal transplantation. |
2016 |
Pediatr. Nephrol. |
pmid:26801944
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Successful treatment of ileal ulcers caused by immunosuppressants in two organ transplant recipients. |
2016 |
World J. Gastroenterol. |
pmid:27350740
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Improved topical delivery of tacrolimus: A novel composite hydrogel formulation for the treatment of psoriasis. |
2016 |
J Control Release |
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Developmental changes of MPA exposure in children. |
2016 |
Pediatr. Nephrol. |
pmid:26743220
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Yingfang F et al. |
Pimecrolimus micelle exhibits excellent therapeutic effect for Keratoconjunctivitis Sicca. |
2016 |
Colloids Surf B Biointerfaces |
pmid:26731192
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Design, Characterization, and In Vivo Pharmacokinetics of Tacrolimus Proliposomes. |
2016 |
AAPS PharmSciTech |
pmid:26729532
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Design and rationale of the ATHENA study--A 12-month, multicentre, prospective study evaluating the outcomes of a de novo everolimus-based regimen in combination with reduced cyclosporine or tacrolimus versus a standard regimen in kidney transplant patients: study protocol for a randomised controlled trial. |
2016 |
Trials |
pmid:26888217
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Choi WJ et al. |
Oral administration of Lactococcus chungangensis inhibits 2,4-dinitrochlorobenzene-induced atopic-like dermatitis in NC/Nga mice. |
2016 |
J. Dairy Sci. |
pmid:27289147
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Bapur Erduran F and Adışen E |
Comparison of the efficacy of 308-nm excimer lamp monotherapy with topical tacrolimus or clobetasol 17-propionate combination therapies in localized vitiligo. |
2016 |
Photodermatol Photoimmunol Photomed |
pmid:27552312
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Assessment of global ischemic/reperfusion and Tacrolimus administration on CA1 region of hippocampus: gene expression profiles of BAX and BCL2 genes. |
2016 |
Bratisl Lek Listy |
pmid:27546370
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Tsuji T et al. |
Therapeutic approach to mite-induced intractable dermatitis using novel immunomodulator FTY720 ointment (fingolimod) in NC/Nga mice. |
2016 |
Allergol Int |
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Speckmann T et al. |
Npas4 Transcription Factor Expression Is Regulated by Calcium Signaling Pathways and Prevents Tacrolimus-induced Cytotoxicity in Pancreatic Beta Cells. |
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J. Biol. Chem. |
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Fang YP et al. |
What is the discrepancy between drug permeation into/across intact and diseased skins? Atopic dermatitis as a model. |
2016 |
Int J Pharm |
pmid:26657274
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Thao le Q et al. |
Pharmaceutical potential of tacrolimus-loaded albumin nanoparticles having targetability to rheumatoid arthritis tissues. |
2016 |
Int J Pharm |
pmid:26657273
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Phosphatase inhibition increases AQP2 accumulation in the rat IMCD apical plasma membrane. |
2016 |
Am. J. Physiol. Renal Physiol. |
pmid:27488997
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Evaluation of 2 Batched Pretreatment Systems for the Measurement of Whole Blood Tacrolimus on the ARCHITECT Immunoassay Analyzer. |
2016 |
Lab Med |
pmid:27474776
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Risk factors for new-onset diabetes mellitus after living donor kidney transplantation in Korea - a retrospective single center study. |
2016 |
BMC Nephrol |
pmid:27473469
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Park JS et al. |
A rapid and sensitive method to determine tacrolimus in rat whole blood using liquid-liquid extraction with mild temperature ultrasonication and LC-MS/MS. |
2016 |
Arch. Pharm. Res. |
pmid:26589688
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Filler G et al. |
Minimum mycophenolic acid levels are associated with donor-specific antibody formation. |
2016 |
Pediatr Transplant |
pmid:26589470
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Scalea JR et al. |
Tacrolimus for the prevention and treatment of rejection of solid organ transplants. |
2016 |
Expert Rev Clin Immunol |
pmid:26588770
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Dabrowska-Zamojcin E et al. |
CCL2 gene polymorphism is associated with post-transplant diabetes mellitus. |
2016 |
Int. Immunopharmacol. |
pmid:26802601
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Sakai R et al. |
A comparison of tacrolimus and cyclosporine combined with methotrexate for graft-versus-host disease prophylaxis, stratified by stem cell source: a retrospective nationwide survey. |
2016 |
Int. J. Hematol. |
pmid:26800676
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Tanriover B et al. |
Acute Rejection Rates and Graft Outcomes According to Induction Regimen among Recipients of Kidneys from Deceased Donors Treated with Tacrolimus and Mycophenolate. |
2016 |
Clin J Am Soc Nephrol |
pmid:27364616
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Ordóñez-Robles M et al. |
Target genes of the Streptomyces tsukubaensis FkbN regulator include most of the tacrolimus biosynthesis genes, a phosphopantetheinyl transferase and other PKS genes. |
2016 |
Appl. Microbiol. Biotechnol. |
pmid:27357227
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Wu SY et al. |
Comprehensive risk assessment for early neurologic complications after liver transplantation. |
2016 |
World J. Gastroenterol. |
pmid:27350733
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Differential influence of tacrolimus and sirolimus on mitochondrial-dependent signaling for apoptosis in pancreatic cells. |
2016 |
Mol. Cell. Biochem. |
pmid:27344165
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Handisurya A et al. |
Conversion from Tacrolimus to Cyclosporine A Improves Glucose Tolerance in HCV-Positive Renal Transplant Recipients. |
2016 |
PLoS ONE |
pmid:26735686
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Tsuji H et al. |
Efficacy and Safety of Grapefruit Juice Intake Accompanying Tacrolimus Treatment in Connective Tissue Disease Patients. |
2016 |
Intern. Med. |
pmid:27301503
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Pizzo HP et al. |
Sirolimus and tacrolimus coefficient of variation is associated with rejection, donor-specific antibodies, and nonadherence. |
2016 |
Pediatr. Nephrol. |
pmid:27286686
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Youssef M et al. |
Asymptomatic papulonodular lesions in zosteriform distribution in an immunocompromised patient. |
2016 |
Int. J. Dermatol. |
pmid:26463835
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Ferjani H et al. |
The evaluate and compare the effects of the Tacrolimus and Sirolimus on the intestinal system using an intestinal cell culture model. |
2016 |
Toxicol. Mech. Methods |
pmid:26460985
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Jebabli N et al. |
Consequences of erroneous phone transmission of tacrolimus blood concentration: A case report. |
2016 |
Therapie |
pmid:27203160
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Characteristic features of tacrolimus-induced lung disease in rheumatoid arthritis patients. |
2016 |
Clin. Rheumatol. |
pmid:25644583
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Nerattini F et al. |
II. Dissociation free energies in drug-receptor systems via nonequilibrium alchemical simulations: application to the FK506-related immunophilin ligands. |
2016 |
Phys Chem Chem Phys |
pmid:27193181
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Tacrolimus trough-level variability predicts long-term allograft survival following kidney transplantation. |
2016 |
J. Nephrol. |
pmid:26374111
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Advagraf(®) , a once-daily prolonged release tacrolimus formulation, in kidney transplantation: literature review and guidelines from a panel of experts. |
2016 |
Transpl. Int. |
pmid:26373896
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Alvarez-ElÃas AC et al. |
CYP3A5 Genotype and Time to Reach Tacrolimus Therapeutic Levels in Renal Transplant Children. |
2016 |
Transplant. Proc. |
pmid:27110018
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Reiner J et al. |
After Intestinal Transplantation Kidney Function Is Impaired by Downregulation of Epithelial Ion Transporters in the Ileum. |
2016 |
Transplant. Proc. |
pmid:27109987
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Comparison of different therapies in high-risk patients with idiopathic membranous nephropathy. |
2016 |
J. Formos. Med. Assoc. |
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Tacrolimus compared with cyclosporine A after haploidentical T-cell replete transplantation with post-infusion cyclophosphamide. |
2016 |
Bone Marrow Transplant. |
pmid:26595078
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Taylor KM and Sparrow MP |
Editorial: tacrolimus vs. anti-tumour necrosis factor agents for moderately to severely active ulcerative colitis. |
2016 |
Aliment. Pharmacol. Ther. |
pmid:27040166
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Lonowski S et al. |
Vitiligo: a potential autoimmune sequela of DRESS syndrome. |
2016 |
Br. J. Dermatol. |
pmid:27038429
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Wang Y et al. |
Preparation, characterization and in vivo evaluation of amorphous tacrolimus nanosuspensions produced using CO2-assisted in situ nanoamorphization method. |
2016 |
Int J Pharm |
pmid:27034003
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Jimbo H et al. |
Telangiectatic lichen sclerosus on the cheek successfully treated with topical tacrolimus. |
2016 |
Eur J Dermatol |
pmid:27033557
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Yan Y et al. |
Robust Axonal Regeneration in a Mouse Vascularized Composite Allotransplant Model Undergoing Delayed Tissue Rejection. |
2016 |
Hand (N Y) |
pmid:28149214
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GarcÃa-Bello JA et al. |
Effect of Immunosuppressive Therapy on Cardiovascular Risk Factor Prevalence in Kidney-Transplanted Children: Comparative Study. |
2016 |
Transplant. Proc. |
pmid:27110020
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Carrillo-Ibarra S et al. |
The Oxidative and Inflammatory State in Patients with Acute Renal Graft Dysfunction Treated with Tacrolimus. |
2016 |
Oxid Med Cell Longev |
pmid:27872679
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Thomusch O et al. |
Rabbit-ATG or basiliximab induction for rapid steroid withdrawal after renal transplantation (Harmony): an open-label, multicentre, randomised controlled trial. |
2016 |
Lancet |
pmid:27871759
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