tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- Am. J. Physiol. Renal Physiol. (1)
- Drug Metab. Dispos. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Sugimoto K et al. | Assessment of Long-Term Efficacy and Safety of Adalimumab in Patients with Ulcerative Colitis: Results from a 6-Year Real-World Clinical Practice. | 2019 | Dig Dis | pmid:30205400 |
| Fu J et al. | Transcriptomic analysis uncovers novel synergistic mechanisms in combination therapy for lupus nephritis. | 2018 | Kidney Int. | pmid:29102373 |
| Kim JP et al. | The effect of full dose composite tissue allotransplantation immunosuppression on allograft motor nerve regeneration in a rat sciatic nerve model. | 2018 | Microsurgery | pmid:28792625 |
| Koppelstaetter C et al. | Effect of cyclosporine, tacrolimus and sirolimus on cellular senescence in renal epithelial cells. | 2018 | Toxicol In Vitro | pmid:29309803 |
| Min S et al. | A randomized clinical trial of age and genotype-guided tacrolimus dosing after pediatric solid organ transplantation. | 2018 | Pediatr Transplant | pmid:30178515 |
| Zegarska J et al. | Evaluation of the Relationship Between Concentrations of Tacrolimus Metabolites, 13-O-Demethyl Tacrolimus and 15-O-Demethyl Tacrolimus, and Clinical and Biochemical Parameters in Kidney Transplant Recipients. | 2018 | Transplant. Proc. | pmid:30177142 |
| La Maestra S et al. | Brain microglia activation induced by intracranial administration of oligonucleotides and its pharmacological modulation. | 2018 | Drug Deliv Transl Res | pmid:29869293 |
| Liang TT et al. | Modeling Analysis of Potential Target of Dolastatin 16 by Computational Virtual Screening. | 2018 | Chem. Pharm. Bull. | pmid:29863061 |
| Wang JL et al. | Delivery of tacrolimus with cationic lipid-assisted nanoparticles for ulcerative colitis therapy. | 2018 | Biomater Sci | pmid:29850666 |
| Zhang T et al. | Association of donor small ubiquitin-like modifier 4 rs237025 genetic variant with tacrolimus elimination in the early period after liver transplantation. | 2018 | Liver Int. | pmid:28941036 |
| Moura Neto A et al. | Clinical Profile of Patients With Diabetes Mellitus and Liver Transplantation: Results After a Multidisciplinary Team Intervention. | 2018 | Transplant. Proc. | pmid:29661438 |
| Crouse L et al. | Pyoderma gangrenosum in an infant: A case report and review of the literature. | 2018 | Pediatr Dermatol | pmid:29656404 |
| Bittersohl H et al. | A simple and highly sensitive on-line column extraction liquid chromatography-tandem mass spectrometry method for the determination of protein-unbound tacrolimus in human plasma samples. | 2018 | J Chromatogr A | pmid:29544893 |
| Solomentsev G et al. | Conformational Entropy of FK506 Binding to FKBP12 Determined by Nuclear Magnetic Resonance Relaxation and Molecular Dynamics Simulations. | 2018 | Biochemistry | pmid:29412644 |
| Li X et al. | Association of the PPARγ/PI3K/Akt pathway with the cardioprotective effects of tacrolimus in myocardial ischemic/reperfusion injury. | 2018 | Mol Med Rep | pmid:29488613 |
| Yeh CT et al. | Seroclearance of hepatitis B surface antigen following hepatitis E exacerbation on chronic hepatitis E and B dual infection in a renal transplant recipient: a case report. | 2018 | J Med Case Rep | pmid:29486803 |
| Takeuchi T et al. | Safety and effectiveness of tacrolimus add-on therapy for rheumatoid arthritis patients without an adequate response to biological disease-modifying anti-rheumatic drugs (DMARDs): Post-marketing surveillance in Japan. | 2018 | Mod Rheumatol | pmid:28649878 |
| Li Y and Feng X | Efficacy and safety of tacrolimus in systemic lupus erythematosus patients with refractory thrombocytopenia: a retrospective study. | 2018 | Lupus | pmid:28566017 |
| Li YM et al. | Soluble Tim-3 and Gal-9 are associated with renal allograft dysfunction in kidney transplant recipients: A cross-sectional study. | 2018 | Int. Immunopharmacol. | pmid:29310109 |
| Lindström L et al. | Risk factors and prognosis for recurrent primary sclerosing cholangitis after liver transplantation: a Nordic Multicentre Study. | 2018 | Scand. J. Gastroenterol. | pmid:29301479 |