tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- Am. J. Physiol. Renal Physiol. (1)
- Drug Metab. Dispos. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Komura Y et al. | Economic assessment of actual prescription of drugs for treatment of atopic dermatitis: Differences between dermatology and pediatrics in large-scale receipt data. | 2018 | J. Dermatol. | pmid:29168213 |
| Akamine Y et al. | A comparison of the effects of CYP3A5 polymorphism on tacrolimus blood concentrations measured by 4 immunoassay methods in renal transplant patients. | 2018 | J Clin Pharm Ther | pmid:28891077 |
| Velioglu A et al. | Late Pulmonary Toxicity Associated With Everolimus in a Renal Transplant Patient and Review of the Literature. | 2018 | Exp Clin Transplant | pmid:27001620 |
| Pflugrad H et al. | Longterm calcineurin inhibitor therapy and brain function in patients after liver transplantation. | 2018 | Liver Transpl. | pmid:29156491 |
| Sugahara S et al. | Integrin, alpha9 subunit blockade suppresses collagen-induced arthritis with minimal systemic immunomodulation. | 2018 | Eur. J. Pharmacol. | pmid:29932925 |
| Wen L et al. | Transient High Pressure in Pancreatic Ducts Promotes Inflammation and Alters Tight Junctions via Calcineurin Signaling in Mice. | 2018 | Gastroenterology | pmid:29928898 |
| Ohtsuki M et al. | Tacrolimus ointment for the treatment of adult and pediatric atopic dermatitis: Review on safety and benefits. | 2018 | J. Dermatol. | pmid:29927498 |
| Castedal M et al. | Steroid-free immunosuppression with low-dose tacrolimus is safe and significantly reduces the incidence of new-onset diabetes mellitus following liver transplantation. | 2018 | Scand. J. Gastroenterol. | pmid:29688072 |
| Niel O and Bastard P | Artificial intelligence improves estimation of tacrolimus area under the concentration over time curve in renal transplant recipients. | 2018 | Transpl. Int. | pmid:29687486 |
| Gmitterová K et al. | Tacrolimus-induced parkinsonism in a patient after liver transplantation - case report. | 2018 | BMC Neurol | pmid:29678162 |
| Ekici Günay N et al. | Administration of Extract (EGb761) Alone and in Combination with FK506 Promotes Liver Regeneration in a Rat Model of Partial Hepatectomy. | 2018 | Balkan Med J | pmid:29553465 |
| Zhang X et al. | Current progress of tacrolimus dosing in solid organ transplant recipients: Pharmacogenetic considerations. | 2018 | Biomed. Pharmacother. | pmid:29550633 |
| Komine N et al. | Influence of CYP3A5 genetic differences in tacrolimus on quantitative interstitial fibrosis and long-term graft function in kidney transplant recipients. | 2018 | Int. Immunopharmacol. | pmid:29550576 |
| Kagaya H et al. | Prediction of Tacrolimus Exposure by CYP3A5 Genotype and Exposure of Co-Administered Everolimus in Japanese Renal Transplant Recipients. | 2018 | Int J Mol Sci | pmid:29547545 |
| Qin X et al. | Multi-center Performance Evaluations of Tacrolimus and Cyclosporine Electrochemiluminescence Immunoassays in the Asia-Pacific Region. | 2018 | Ann Lab Med | pmid:29214751 |
| Fu Q et al. | Risk Factors for Acute Rejection After Deceased Donor Kidney Transplantation in China. | 2018 | Transplant. Proc. | pmid:30316380 |
| Konno O et al. | Early Outcomes of Living-Donor Kidney Transplantation With Immunosuppression Therapy Induction With Tacrolimus Extended-Release: A Comparison With Cyclosporine. | 2018 | Transplant. Proc. | pmid:30316378 |
| Tsujimura K et al. | Effect of Influenza Vaccine in Patients With Kidney Transplant. | 2018 | Transplant. Proc. | pmid:30316375 |
| Yu M et al. | Pharmacokinetics, Pharmacodynamics and Pharmacogenetics of Tacrolimus in Kidney Transplantation. | 2018 | Curr. Drug Metab. | pmid:29380698 |
| Kim JH et al. | Increased Exposure of Tacrolimus by Co-administered Mycophenolate Mofetil: Population Pharmacokinetic Analysis in Healthy Volunteers. | 2018 | Sci Rep | pmid:29374217 |