First MR |
Transplantation in the nineties. |
1992 |
Transplantation |
pmid:1370734
|
Naito M et al. |
Reversal of multidrug resistance by an immunosuppressive agent FK-506. |
1992 |
Cancer Chemother. Pharmacol. |
pmid:1370765
|
Yem AW et al. |
The Hsp56 component of steroid receptor complexes binds to immobilized FK506 and shows homology to FKBP-12 and FKBP-13. |
1992 |
J. Biol. Chem. |
pmid:1371107
|
Park ST et al. |
PPIase catalysis by human FK506-binding protein proceeds through a conformational twist mechanism. |
1992 |
J. Biol. Chem. |
pmid:1371117
|
Bishop DK and Li W |
Cyclosporin A and FK506 mediate differential effects on T cell activation in vivo. |
1992 |
J. Immunol. |
pmid:1371128
|
Hatfield SM and Roehm NW |
Cyclosporine and FK506 inhibition of murine mast cell cytokine production. |
1992 |
J. Pharmacol. Exp. Ther. |
pmid:1371158
|
Takaya S et al. |
The adverse impact on liver transplantation of using positive cytotoxic crossmatch donors. |
1992 |
Transplantation |
pmid:1371195
|
Francavilla A et al. |
Inhibition of liver, kidney, and intestine regeneration by rapamycin. |
1992 |
Transplantation |
pmid:1371198
|
Ueno M et al. |
Immunosuppressive effect in combination therapy of cyclosporine A, FK 506, and 15-deoxyspergualin on pancreatic islet xenotransplantation. |
1992 |
Transplant. Proc. |
pmid:1373546
|
Matsuzaki T et al. |
Liver transplantation for diethylnitrosamine-induced hepatocellular carcinoma in rats. |
1992 |
Transplant. Proc. |
pmid:1373547
|
Vincent SH et al. |
In vitro metabolism of FK-506 in rat, rabbit, and human liver microsomes: identification of a major metabolite and of cytochrome P450 3A as the major enzymes responsible for its metabolism. |
1992 |
Arch. Biochem. Biophys. |
pmid:1373595
|
Liu J et al. |
Inhibition of T cell signaling by immunophilin-ligand complexes correlates with loss of calcineurin phosphatase activity. |
1992 |
Biochemistry |
pmid:1373650
|
Adachi A et al. |
Immunosuppressive effect of FK506 on experimental allergic neuritis in Lewis rats: change of T cell subsets. |
1992 |
Intern. Med. |
pmid:1373661
|
Fruman DA et al. |
Calcineurin phosphatase activity in T lymphocytes is inhibited by FK 506 and cyclosporin A. |
1992 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:1373887
|
Lake JR et al. |
Maintenance immunosuppression after liver transplantation. |
1992 |
Semin. Liver Dis. |
pmid:1373916
|
Bernstein L and Daviss SR |
Organic anxiety disorder with symptoms of akathisia in a patient treated with the immunosuppressant FK506. |
1992 |
Gen Hosp Psychiatry |
pmid:1376291
|
Hatfield SM et al. |
Rapamycin and FK506 differentially inhibit mast cell cytokine production and cytokine-induced proliferation and act as reciprocal antagonists. |
1992 |
J. Pharmacol. Exp. Ther. |
pmid:1376361
|
Ericzon BG et al. |
The effect of FK506 treatment on pancreaticoduodenal allotransplantation in the primate. |
1992 |
Transplantation |
pmid:1376501
|
Tze WJ et al. |
FK 506--an effective immunosuppressant in achieving long-term functional islet allograft survival in diabetic rats. |
1992 |
Transplant. Proc. |
pmid:1376509
|
Yasunami Y et al. |
Induction of donor-specific unresponsiveness in rat islet allografts by FK 506. |
1992 |
Transplant. Proc. |
pmid:1376510
|
Kai N et al. |
A study on the timing of immunologic priming in autoimmune insulitis in NOD mice. |
1992 |
Transplant. Proc. |
pmid:1376511
|
Ricordi C et al. |
Effect of FK 506 on human pancreatic islets following renal subcapsular transplantation in diabetic nude mice. |
1992 |
Transplant. Proc. |
pmid:1376512
|
Hisanaga M et al. |
Successful combination therapy with FK 506 and 15-deoxyspergualin in pancreatic islet xenografting. |
1992 |
Transplant. Proc. |
pmid:1376513
|
Takaya S et al. |
Liver transplantation in positive cytotoxic crossmatch cases using FK506, high-dose steroids, and prostaglandin E1. |
1992 |
Transplantation |
pmid:1279851
|
Partaledis JA et al. |
Saccharomyces cerevisiae contains a homolog of human FKBP-13, a membrane-associated FK506/rapamycin binding protein. |
1992 |
Yeast |
pmid:1279908
|
Ozawa K et al. |
An appraisal of pediatric liver transplantation from living relatives. Initial clinical experiences in 20 pediatric liver transplantations from living relatives as donors. |
1992 |
Ann. Surg. |
pmid:1280074
|
Akutsu I et al. |
[Inhibitory effects of cyclosporin A and FK-506 on eosinophil chemotactic factor activity in culture supernatants of mononuclear cells from asthmatics]. |
1992 |
Arerugi |
pmid:1280086
|
Bergstrand H and Lundquist B |
Human basophil histamine release is differently affected by inhibitors of calmodulin, diacylglycerol kinase and peptidyl prolyl cis-trans isomerase in a secretagogue specific manner. |
1992 |
Allergy |
pmid:1280915
|
Barry JM |
Immunosuppressive drugs in renal transplantation. A review of the regimens. |
1992 |
Drugs |
pmid:1281071
|
Stiff DD et al. |
Metabolism of FK 506 in differentially induced rat liver microsomes. |
1992 |
Res. Commun. Chem. Pathol. Pharmacol. |
pmid:1281332
|
Foor F et al. |
Calcineurin mediates inhibition by FK506 and cyclosporin of recovery from alpha-factor arrest in yeast. |
1992 |
Nature |
pmid:1281518
|
Goldfeld AE et al. |
Transcription of the tumor necrosis factor alpha gene is rapidly induced by anti-immunoglobulin and blocked by cyclosporin A and FK506 in human B cells. |
1992 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:1281550
|
High KP and Handschumacher RE |
Immunity, microbial pathogenesis, and immunophilins: finding the keys, now where are the locks? |
1992 |
Infect Agents Dis |
pmid:1285413
|
Akutsu I et al. |
[Inhibitory effect of inhaled FK-506 on increased bronchial responsiveness and eosinophil infiltration in the airway mucosa]. |
1992 |
Arerugi |
pmid:1377905
|
Takaori K et al. |
A comparative study on immunosuppressive effects of cyclosporin A and FK 506 on peripheral blood lymphocytes in dogs. |
1992 |
Biotherapy |
pmid:1377926
|
Murthy JN et al. |
Radioreceptor assay for quantifying FK-506 immunosuppressant in whole blood. |
1992 |
Clin. Chem. |
pmid:1377995
|
Takai K et al. |
Effects of FK506 on rat thymic epithelial cells; immunohistochemical study. |
1992 |
Thymus |
pmid:1378235
|
Dutz JP et al. |
Effects of cognate peptides on cytolytic and proliferative activities of cloned cytotoxic T lymphocytes. |
1992 |
Int. Immunol. |
pmid:1378297
|
Kenmochi T et al. |
[The effect of FK506 on segmental pancreas allograft in mongrel dogs]. |
1992 |
Nihon Geka Gakkai Zasshi |
pmid:1378526
|
Mouzaki A et al. |
Cyclosporin A and FK506 prevent the derepression of the IL-2 gene in mitogen-induced primary T lymphocytes. |
1992 |
Cytokine |
pmid:1378764
|
Kahan BD |
Cyclosporin A, FK506, rapamycin: the use of a quantitative analytic tool to discriminate immunosuppressive drug interactions. |
1992 |
J. Am. Soc. Nephrol. |
pmid:1379841
|
Lauerma AI et al. |
Inhibition of contact allergy reactions by topical FK506. |
1992 |
Lancet |
pmid:1380111
|
Steiner JP et al. |
High brain densities of the immunophilin FKBP colocalized with calcineurin. |
1992 |
Nature |
pmid:1380130
|
Aperia A et al. |
Calcineurin mediates alpha-adrenergic stimulation of Na+,K(+)-ATPase activity in renal tubule cells. |
1992 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:1380157
|
Nielsen JB et al. |
Yeast FKBP-13 is a membrane-associated FK506-binding protein encoded by the nonessential gene FKB2. |
1992 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:1380159
|
Calvo V et al. |
Interleukin 2 stimulation of p70 S6 kinase activity is inhibited by the immunosuppressant rapamycin. |
1992 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:1380162
|
Price DJ et al. |
Rapamycin-induced inhibition of the 70-kilodalton S6 protein kinase. |
1992 |
Science |
pmid:1380182
|
Granelli-Piperno A |
SRC-related proto-oncogenes and transcription factors in primary human T cells: modulation by cyclosporin A and FK506. |
1992 |
J. Autoimmun. |
pmid:1380242
|
Yasutomi D et al. |
Inhibition of programmed cell death by cyclosporin A; preferential blocking of cell death induced by signals via TCR/CD3 complex and its mode of action. |
1992 |
Immunology |
pmid:1383138
|
Ruff VA et al. |
Tissue distribution and cellular localization of hsp56, an FK506-binding protein. Characterization using a highly specific polyclonal antibody. |
1992 |
J. Biol. Chem. |
pmid:1383222
|
Wiederrecht G et al. |
Characterization of high molecular weight FK-506 binding activities reveals a novel FK-506-binding protein as well as a protein complex. |
1992 |
J. Biol. Chem. |
pmid:1383226
|
Morris RE |
Immunopharmacology of new xenobiotic immunosuppressive molecules. |
1992 |
Semin. Nephrol. |
pmid:1384096
|
Hendey B et al. |
Inhibition of neutrophil chemokinesis on vitronectin by inhibitors of calcineurin. |
1992 |
Science |
pmid:1384129
|
Roberti I et al. |
Evidence that the systematic analysis of bile cytology permits monitoring of hepatic allograft rejection. |
1992 |
Transplantation |
pmid:1384182
|
Langrehr JM et al. |
Evidence that indefinite survival of small bowel allografts achieved by a brief course of cyclosporine or FK506 is not due to systemic hyporesponsiveness. |
1992 |
Transplantation |
pmid:1384185
|
McCarthy SA et al. |
The effects of immunosuppressive drugs on the regulation of activation-induced apoptotic cell death in thymocytes. |
1992 |
Transplantation |
pmid:1384186
|
Mizuno K et al. |
Modulation of multidrug resistance by immunosuppressive agents: cyclosporin analogues, FK506 and mizoribine. |
1992 Jan-Feb |
Anticancer Res. |
pmid:1373592
|
Arai S et al. |
The impact of FK506 on graft coronary disease of rat cardiac allograft--a comparison with cyclosporine. |
1992 Jul-Aug |
J. Heart Lung Transplant. |
pmid:1379829
|
Fagiuoli S et al. |
FK 506: a new immunosuppressive agent for organ transplantation. Pharmacology, mechanism of action and clinical applications. |
1992 Jul-Aug |
Ital J Gastroenterol |
pmid:1381245
|
Tong J et al. |
Effect of FK-506 and cyclosporin A on in vitro CFU-GM growth in severe aplastic anemia patients. |
1992 Jul-Aug |
Haematologica |
pmid:1385279
|
Nazer H et al. |
FK 506 associated disorders in liver transplantation. |
1992 May-Jun |
J. Gastroenterol. Hepatol. |
pmid:1377038
|
Bowman H and Lennard TW |
Immunosuppressive drugs. |
1992 Nov 4-17 |
Br J Hosp Med |
pmid:1282440
|
Sattler M et al. |
Cytochrome P-450 3A enzymes are responsible for biotransformation of FK506 and rapamycin in man and rat. |
1992 Sep-Oct |
Drug Metab. Dispos. |
pmid:1385058
|
|
Japanese study of FK 506 on kidney transplantation: results of late phase II study. |
1993 |
Transplant. Proc. |
pmid:7679831
|
Kobayashi M et al. |
Production of monoclonal antibody against recombinant human FKBP-12 and subcellular localization of FKBP-12 in human mononuclear and polymorphonuclear cells. |
1993 |
Transplant. Proc. |
pmid:7679832
|
Kuroki H et al. |
Effect of FK 506 and donor-specific blood transfusion on the rat composite tissue limb allograft and the mechanism of long-term graft survival. |
1993 |
Transplant. Proc. |
pmid:7679833
|
Egan DA et al. |
Equilibrium denaturation of recombinant human FK binding protein in urea. |
1993 |
Biochemistry |
pmid:7680574
|
Lionetti P et al. |
Activation of mucosal V beta 3+ T cells and tissue damage in human small intestine by the bacterial superantigen, Staphylococcus aureus enterotoxin B. |
1993 |
Eur. J. Immunol. |
pmid:7680613
|
Nelson PA et al. |
Immunosuppressive activity of [MeBm2t]1-, D-diaminobutyryl-8-, and D-diaminopropyl-8-cyclosporin analogues correlates with inhibition of calcineurin phosphatase activity. |
1993 |
J. Immunol. |
pmid:7680683
|
Piekoszewski W and Jusko WJ |
Plasma protein binding of tacrolimus in humans. |
1993 |
J Pharm Sci |
pmid:7680714
|
Ishizuka J et al. |
Effects of FK506 and cyclosporine on dynamic insulin secretion from isolated dog pancreatic islets. |
1993 |
Transplantation |
pmid:7506454
|
Dhar DK et al. |
Effective prevention of ischemic injury of the dearterialized canine liver by FK506 pretreatment. |
1993 |
Transplantation |
pmid:7506456
|
Fabrega AJ et al. |
Enhancement of allograft survival by single intraoperative donor-specific blood transfusion combined with FK506. |
1993 |
Transplantation |
pmid:7506458
|
Jain A et al. |
FK506 and pregnancy in liver transplant patients. |
1993 |
Transplantation |
pmid:7506459
|
Liu J |
FK506 and cyclosporin, molecular probes for studying intracellular signal transduction. |
1993 |
Immunol. Today |
pmid:7691065
|
Mori T et al. |
FK-506: a new immunosuppressive agent, failed to reduce cerebral vasospasm after experimental subarachnoid hemorrhage. |
1993 |
J. Vet. Med. Sci. |
pmid:7691190
|
Distant DA and Gonwa TA |
The kidney in liver transplantation. |
1993 |
J. Am. Soc. Nephrol. |
pmid:7691205
|
Muthukkumar S et al. |
Elevation of cytosolic calcium is sufficient to induce growth inhibition in a B cell lymphoma. |
1993 |
Eur. J. Immunol. |
pmid:7691606
|
Sperr WR et al. |
[Effector cells in allergy: biological principles and new pharmacologic concepts]. |
1993 |
Wien. Klin. Wochenschr. |
pmid:7508662
|
Dawson TM et al. |
Immunosuppressant FK506 enhances phosphorylation of nitric oxide synthase and protects against glutamate neurotoxicity. |
1993 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:7694293
|
Spencer DM et al. |
Controlling signal transduction with synthetic ligands. |
1993 |
Science |
pmid:7694365
|
Travis J |
Making molecular matches in the cell. |
1993 |
Science |
pmid:7694368
|
Jusko WJ and Kobayashi M |
Therapeutic monitoring of tacrolimus (FK 506) |
1993 |
Ther Drug Monit |
pmid:7694395
|
Wagner JA et al. |
Failure of FK 506 to suppress the T cell-mediated immunity of mice to Listeria monocytogenes. |
1993 |
Clin. Exp. Immunol. |
pmid:7685672
|
Pilot-Matias TJ et al. |
High-level synthesis of the 12-kDa human FK506-binding protein in Escherichia coli using translational coupling. |
1993 |
Gene |
pmid:7685727
|
Akamine S et al. |
[Effect of FK-506 on bronchial healing of canine lung allografts]. |
1993 |
Nihon Kyobu Geka Gakkai Zasshi |
pmid:7685803
|
Partaledis JA and Berlin V |
The FKB2 gene of Saccharomyces cerevisiae, encoding the immunosuppressant-binding protein FKBP-13, is regulated in response to accumulation of unfolded proteins in the endoplasmic reticulum. |
1993 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:7685904
|
Emond JC et al. |
Improved results of living-related liver transplantation with routine application in a pediatric program. |
1993 |
Transplantation |
pmid:7682738
|
Kai N et al. |
Prevention of insulitis and diabetes in nonobese diabetic mice by administration of FK506. |
1993 |
Transplantation |
pmid:7682740
|
Hirakawa K et al. |
[The effect of perioperative portal venous inoculation with donor lymphocytes in combination with immunosuppressive agents on rat cardiac allograft survivals]. |
1993 |
Nihon Geka Gakkai Zasshi |
pmid:7688065
|
Entani C et al. |
Effect of a novel immunosuppressant, FK506, on spontaneous lupus nephritis in MRL/MpJ-lpr/lpr mice. |
1993 |
Nephron |
pmid:7688103
|
Ueki M et al. |
Diabetogenic effects of FK506 on renal subcapsular islet isografts in rat. |
1993 |
Diabetes Res. Clin. Pract. |
pmid:7688276
|
Abu-Elmagd K et al. |
Resolution of severe pyoderma gangrenosum in a patient with streaking leukocyte factor disease after treatment with tacrolimus (FK 506). |
1993 |
Ann. Intern. Med. |
pmid:7689802
|
Christensen BG |
FK-506: its role in immunosuppression. |
1993 |
Ann. N. Y. Acad. Sci. |
pmid:7689803
|
Kino T and Goto T |
Discovery of FK-506 and update. |
1993 |
Ann. N. Y. Acad. Sci. |
pmid:7689804
|
Parsons WH et al. |
FK-506--a novel immunosuppressant. |
1993 |
Ann. N. Y. Acad. Sci. |
pmid:7689805
|
Kawai M et al. |
Structure-activity profiles of macrolactam immunosuppressant FK-506 analogues. |
1993 |
FEBS Lett. |
pmid:7678400
|
Van Duyne GD et al. |
Atomic structures of the human immunophilin FKBP-12 complexes with FK506 and rapamycin. |
1993 |
J. Mol. Biol. |
pmid:7678431
|
Meadows RP et al. |
Three-dimensional structure of the FK506 binding protein/ascomycin complex in solution by heteronuclear three- and four-dimensional NMR. |
1993 |
Biochemistry |
pmid:7678499
|
Jiang H et al. |
Anti-tumor-promoting action of FK506, a potent immunosuppressive agent. |
1993 |
Carcinogenesis |
pmid:7678785
|