Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with tacrolimus
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Laeijendecker R et al. | A comparison of treatment of oral lichen planus with topical tacrolimus and triamcinolone acetonide ointment. | 2006 | Acta Derm. Venereol. | pmid:16710580 |
Bovenschen HJ | Novel treatment for cheilitis glandularis. | 2009 | Acta Derm. Venereol. | pmid:19197557 |
Seo SR et al. | Disrupted Skin Barrier is Associated with Burning Sensation after Topical Tacrolimus Application in Atopic Dermatitis. | 2017 | Acta Derm. Venereol. | pmid:28512670 |
Benedix F et al. | Response of ulcerated necrobiosis lipoidica to clofazimine. | 2009 | Acta Derm. Venereol. | pmid:19997705 |
Weisshaar E | Successful treatment of genital pruritus using topical immunomodulators as a single therapy in multi-morbid patients. | 2008 | Acta Derm. Venereol. | pmid:18311464 |
Hartmann A et al. | Occlusive treatment enhances efficacy of tacrolimus 0.1% ointment in adult patients with vitiligo: results of a placebo-controlled 12-month prospective study. | 2008 | Acta Derm. Venereol. | pmid:18779885 |
Virgili A et al. | Vulvar lichen sclerosus: 11 women treated with tacrolimus 0.1% ointment. | 2007 | Acta Derm. Venereol. | pmid:17225019 |
Ambo M | Relapsing Kaposi's varicelliform eruption and herpes simplex following facial tacrolimus treatment for atopic dermatitis. | 2002 | Acta Derm. Venereol. | pmid:12353724 |
Yamamoto T and Nishioka K | Topical tacrolimus is effective for facial lesions of psoriasis. | 2000 Nov-Dec | Acta Derm. Venereol. | pmid:11243645 |
Lee HY et al. | Oral mucous membrane pemphigoid: complete response to topical tacrolimus. | 2011 | Acta Derm. Venereol. | pmid:21597668 |