tacrolimus

Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.

Cross Reference

Introduction

To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with tacrolimus?

tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with tacrolimus

MeSH term MeSH ID Detail
AIDS-Associated Nephropathy D016263 1 associated lipids
Feline Acquired Immunodeficiency Syndrome D016181 1 associated lipids
Digestive System Fistula D016154 1 associated lipids
Ichthyosiform Erythroderma, Congenital D016113 1 associated lipids
Epidermolysis Bullosa Dystrophica D016108 1 associated lipids
Simian Acquired Immunodeficiency Syndrome D016097 4 associated lipids
Uveitis, Intermediate D015867 3 associated lipids
Uveitis, Posterior D015866 5 associated lipids
Oculomotor Nerve Diseases D015840 1 associated lipids
Vestibular Diseases D015837 2 associated lipids
Ocular Motility Disorders D015835 2 associated lipids
Eye Infections, Viral D015828 1 associated lipids
Eye Infections, Fungal D015821 2 associated lipids
Eye Diseases, Hereditary D015785 1 associated lipids
Osteoporosis, Postmenopausal D015663 4 associated lipids
HIV Infections D015658 20 associated lipids
Histiocytosis D015614 2 associated lipids
Paraparesis, Tropical Spastic D015493 1 associated lipids
Leukemia, Myeloid, Chronic-Phase D015466 1 associated lipids
Leukemia, Myelogenous, Chronic, BCR-ABL Positive D015464 17 associated lipids
Leukemia-Lymphoma, Adult T-Cell D015459 25 associated lipids
Leukemia, T-Cell D015458 23 associated lipids
Leukemia, Biphenotypic, Acute D015456 2 associated lipids
Leprosy, Borderline D015439 3 associated lipids
Panniculitis, Lupus Erythematosus D015435 1 associated lipids
Glomerulonephritis, Membranous D015433 6 associated lipids
Glomerulonephritis, Membranoproliferative D015432 3 associated lipids
Weight Loss D015431 56 associated lipids
Weight Gain D015430 101 associated lipids
Reperfusion Injury D015427 65 associated lipids
Scleritis D015423 3 associated lipids
Dry Eye Syndromes D015352 10 associated lipids
Discitis D015299 2 associated lipids
Tumor Lysis Syndrome D015275 2 associated lipids
Churg-Strauss Syndrome D015267 2 associated lipids
Carcinoma, Merkel Cell D015266 2 associated lipids
Inflammatory Bowel Diseases D015212 9 associated lipids
Cholangitis, Sclerosing D015209 1 associated lipids
Dementia, Vascular D015140 7 associated lipids
Wounds, Stab D014951 3 associated lipids
West Nile Fever D014901 1 associated lipids
Vomiting D014839 21 associated lipids
Vitiligo D014820 2 associated lipids
Vision Disorders D014786 10 associated lipids
Viremia D014766 4 associated lipids
Venous Insufficiency D014689 2 associated lipids
Vasculitis D014657 14 associated lipids
Vascular Diseases D014652 16 associated lipids
Uveomeningoencephalitic Syndrome D014607 1 associated lipids
Uveitis, Anterior D014606 11 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with tacrolimus

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with tacrolimus?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with tacrolimus?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with tacrolimus?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with tacrolimus?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with tacrolimus?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with tacrolimus

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Per page 10 20 50 100 | Total 15051
Authors Title Published Journal PubMed Link
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Standaert RF et al. Molecular cloning and overexpression of the human FK506-binding protein FKBP. 1990 Nature pmid:1696686
Tropschug M et al. Isolation and sequence of an FK506-binding protein from N. crassa which catalyses protein folding. 1990 Nature pmid:1696687
Randall T New antirejection drugs anticipated. 1990 JAMA pmid:1696999
Metcalfe S et al. FK 506 and cyclosporine A: early effects on activation and gene induction in mouse spleen cells. 1990 Transplant. Proc. pmid:1697107
Morris RE et al. A study of the contrasting effects of cyclosporine, FK 506, and rapamycin on the suppression of allograft rejection. 1990 Transplant. Proc. pmid:1697111
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Takada K et al. Determination of a novel potent immunosuppressant (FK-506) in rat serum and lymph by high-performance liquid chromatography with chemiluminescence detection. 1990 J. Chromatogr. pmid:1703552
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