Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with tacrolimus
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Lee WS et al. | Tacrolimus regulates endoplasmic reticulum stress-mediated osteoclastogenesis and inflammation: In vitro and collagen-induced arthritis mouse model. | 2018 | Cell Biol. Int. | pmid:28833755 |
Huang F et al. | Pharmacokinetic Interaction between Faldaprevir and Cyclosporine or Tacrolimus in Healthy Volunteers: A Prospective, Open-Label, Fixed-Sequence, Crossover Study. | 2018 | Basic Clin. Pharmacol. Toxicol. | pmid:29427400 |
Mithani Z et al. | De Novo Donor-Specific Antibody Formation in Tacrolimus-Based, Mycophenolate Versus Mammalian Target of Rapamycin Immunosuppressive Regimens. | 2018 | Exp Clin Transplant | pmid:28332959 |
Vandenbussche C et al. | Tacrolimus-induced nephrotoxicity in mice is associated with microRNA deregulation. | 2018 | Arch. Toxicol. | pmid:29362864 |
Thoms S et al. | Tacrolimus inhibits angiogenesis and induces disaggregation of endothelial cells in spheroids - Toxicity testing in a 3D cell culture approach. | 2018 | Toxicol In Vitro | pmid:30048735 |
Marquet P et al. | Pharmacokinetic Therapeutic Drug Monitoring of Advagraf in More Than 500 Adult Renal Transplant Patients, Using an Expert System Online. | 2018 | Ther Drug Monit | pmid:29505493 |
Chung YW et al. | Tacrolimus-Induced Apoptosis is Mediated by Endoplasmic Reticulum-derived Calcium-dependent Caspases-3,-12 in Jurkat Cells. | 2018 | Transplant. Proc. | pmid:29731088 |
Youssef A et al. | Angiolymphoid hyperplasia with eosinophilia: a case report. | 2018 | J Med Case Rep | pmid:29606120 |
Hu R et al. | CYP3A5*3 and ABCB1 61A>G Significantly Influence Dose-adjusted Trough Blood Tacrolimus Concentrations in the First Three Months Post-Kidney Transplantation. | 2018 | Basic Clin. Pharmacol. Toxicol. | pmid:29603629 |
Schuh MJ and Massoglia G | Pharmacist Impact on Tacrolimus Serum Concentrations in Liver Transplant Patients. | 2018 | Consult Pharm | pmid:29789048 |