tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- Am. J. Physiol. Renal Physiol. (1)
- Drug Metab. Dispos. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
|---|
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Randhawa PS et al. | Clinical significance of renal biopsies showing concurrent acute rejection and tacrolimus-associated tubular vacuolization. | 1999 | Transplantation | pmid:9921801 |
| Yoshida A et al. | Studies of repeated administration of FK-506 on myocardial metabolism in rats. | 1998 | J Toxicol Sci | pmid:9922943 |
| Wingard JR et al. | Relationship of tacrolimus (FK506) whole blood concentrations and efficacy and safety after HLA-identical sibling bone marrow transplantation. | 1998 | Biol. Blood Marrow Transplant. | pmid:9923414 |
| Cai Q et al. | Reduction of infarct size in isolated rat heart by CsA and FK506: possible role of phosphatase inhibition. | 1998 | Cardiovasc Drugs Ther | pmid:9926283 |
| Honoré P et al. | [Liver transplantation: experiences and results of a program at the University of Liege]. | 1998 | Rev Med Liege | pmid:9927867 |
| Al-Nasser IA | In vivo prevention of adriamycin cardiotoxicity by cyclosporin A or FK506. | 1998 | Toxicology | pmid:9928632 |
| Takeda Y et al. | Mechanisms of FK 506-induced hypertension in the rat. | 1999 | Hypertension | pmid:9931093 |
| Hebebrand D et al. | [Genetic methods in experimental xenogenic nerve transplantation]. | 1998 | Langenbecks Arch Chir Suppl Kongressbd | pmid:9931858 |
| Nakahama H et al. | Effect of a novel immunosuppressant, FK 506, on autoimmune glomerulonephritis in Brown Norway rats. | 1999 | Nephron | pmid:9933758 |
| Hebert MF et al. | Effects of rifampin on tacrolimus pharmacokinetics in healthy volunteers. | 1999 | J Clin Pharmacol | pmid:9987705 |
| Mrowietz U et al. | The novel ascomycin derivative SDZ ASM 981 is effective for psoriasis when used topically under occlusion. | 1998 | Br. J. Dermatol. | pmid:9990361 |