tacrolimus

Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.

Cross Reference

Introduction

To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with tacrolimus?

tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with tacrolimus

MeSH term MeSH ID Detail
Denys-Drash Syndrome D030321 1 associated lipids
Hypophosphatemia D017674 1 associated lipids
Moyamoya Disease D009072 1 associated lipids
Latent Tuberculosis D055985 1 associated lipids
Leukoplakia D007971 1 associated lipids
Oculomotor Nerve Diseases D015840 1 associated lipids
Scorpion Stings D065008 1 associated lipids
Esophageal Perforation D004939 1 associated lipids
Mediastinitis D008480 2 associated lipids
Coproporphyria, Hereditary D046349 1 associated lipids
Ileus D045823 3 associated lipids
Rectal Diseases D012002 1 associated lipids
Angiolymphoid Hyperplasia with Eosinophilia D000796 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with tacrolimus

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with tacrolimus?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with tacrolimus?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with tacrolimus?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with tacrolimus?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with tacrolimus?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with tacrolimus

Download all related citations
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Authors Title Published Journal PubMed Link
Zhu L et al. Effects of CYP3A5 genotypes, ABCB1 C3435T and G2677T/A polymorphism on pharmacokinetics of Tacrolimus in Chinese adult liver transplant patients. 2015 Xenobiotica pmid:25869250
Miura M et al. Comparison of enantioselective disposition of rabeprazole versus lansoprazole in renal-transplant recipients who are CYP2C19 extensive metabolizers. 2005 Xenobiotica pmid:16012079
Gupta AS et al. Pyoderma Gangrenosum of the Scalp: A Rare Clinical Variant. 2018 Wounds pmid:29481333
Kiyama T et al. Tacrolimus enhances colon anastomotic healing in rats. 2002 Sep-Oct Wound Repair Regen pmid:12406167
Yang J et al. Zinc finger protein A20 protects rats against chronic liver allograft dysfunction. 2012 World J. Gastroenterol. pmid:22826618
Zhou J et al. Conversion to sirolimus immunosuppression in liver transplantation recipients with hepatocellular carcinoma: Report of an initial experience. 2006 World J. Gastroenterol. pmid:16718799
Filipec Kanizaj T and Mijic M Inflammatory bowel disease in liver transplanted patients. 2017 World J. Gastroenterol. pmid:28566881
Kang YZ et al. Autoimmune hepatitis-primary biliary cirrhosis concurrent with biliary stricture after liver transplantation. 2015 World J. Gastroenterol. pmid:25717264
Liu F et al. Tacrolimus dosage requirements in living donor liver transplant recipients with small-for-size grafts. 2009 World J. Gastroenterol. pmid:19701975
Schumacher G et al. Sirolimus inhibits growth of human hepatoma cells alone or combined with tacrolimus, while tacrolimus promotes cell growth. 2005 World J. Gastroenterol. pmid:15770715
Takeichi T et al. Effect of ONO-4057 and tacrolimus on ischemia-reperfusion injury of the liver. 2009 World J. Gastroenterol. pmid:19960569
Jiang JW et al. Optimal immunosuppressor induces stable gut microbiota after liver transplantation. 2018 World J. Gastroenterol. pmid:30228781
Lan X et al. Efficacy of immunosuppression monotherapy after liver transplantation: a meta-analysis. 2014 World J. Gastroenterol. pmid:25232269
Del Bello A et al. High tacrolimus intra-patient variability is associated with graft rejection, and donor-specific antibodies occurrence after liver transplantation. 2018 World J. Gastroenterol. pmid:29713132
Akamatsu N et al. Late-onset acute rejection after living donor liver transplantation. 2006 World J. Gastroenterol. pmid:17075982
Wietzke-Braun P et al. Initial steroid-free immunosuppression after liver transplantation in recipients with hepatitis C virus related cirrhosis. 2004 World J. Gastroenterol. pmid:15259068
Higashi H et al. First successful perinatal management of pregnancy after ABO-incompatible liver transplantation. 2017 World J. Gastroenterol. pmid:28210092
Shao ZY et al. Prophylaxis of chronic kidney disease after liver transplantation--experience from west China. 2012 World J. Gastroenterol. pmid:22408361
Indriolo A and Ravelli P Clinical management of inflammatory bowel disease in the organ recipient. 2014 World J. Gastroenterol. pmid:24707135
Shen T et al. Reversible sinusoidal obstruction syndrome associated with tacrolimus following liver transplantation. 2015 World J. Gastroenterol. pmid:26034381