Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with tacrolimus
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Zhao X et al. | [A retrospective cohort study regarding the effect of sirolimus-based immunosuppression protocol on the long-term survival of hepatocellular carcinoma patients after liver transplantation]. | 2014 | Zhonghua Wai Ke Za Zhi | pmid:24924566 |
Ju WQ et al. | [Two-dose steroid combined with two-dose daclizumab and tacrolimus regimen in liver transplant recipients]. | 2009 | Zhonghua Wai Ke Za Zhi | pmid:19781270 |
Chen YP et al. | [The clinical efficacy and safety of tacrolimus in patients with myasthenia gravis]. | 2013 | Zhonghua Nei Ke Za Zhi | pmid:24266997 |
Sun L et al. | [Effect of FK506 on the cavernous nerve regeneration after injury]. | 2005 | Zhonghua Nan Ke Xue | pmid:15755036 |
Cao ZG et al. | [Effects of different immunodepressants on the sperm parameters of kidney transplant recipients]. | 2006 | Zhonghua Nan Ke Xue | pmid:16755867 |
Zhao S et al. | [Effects of tacrolimus (FK506) on heat-shock proteins 70, Bcl-2 and Bax expression in nervous tissue of acrylamide-induced rat]. | 2010 | Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi | pmid:20465949 |
Sun YJ and Sun Z | [Treatment of erosive oral lichen planus with topical tacrolimus]. | 2010 | Zhonghua Kou Qiang Yi Xue Za Zhi | pmid:20450689 |
Zhang J et al. | [Effects of sirolimus on the growth of transplanted hepatocellular carcinoma]. | 2009 | Zhonghua Gan Zang Bing Za Zhi | pmid:19567017 |
Qian SK et al. | [The prevention and management of cerebrovascular complications in nine cases after orthotopic liver transplantation]. | 2005 | Zhonghua Gan Zang Bing Za Zhi | pmid:16313741 |
Huang K et al. | [Prophylaxis and treatment of chronic graft versus host disease]. | 2005 | Zhonghua Er Ke Za Zhi | pmid:15833186 |
Deng Z et al. | [Early diagnosis and comprehensive treatments of post-transplantation lymphoproliferative disorder after pediatric liver transplantation]. | 2014 | Zhonghua Er Ke Za Zhi | pmid:25224233 |
Zhou DJ and Wu XC | [Meta-analysis of calcineurin inhibitor in the treatment of lupus nephritis]. | 2011 | Zhonghua Er Ke Za Zhi | pmid:21624207 |
Yao SH et al. | [Clinical application of tacrolimus with low-dose prednisone in 21 children with steroid-resistant nephrotic syndrome]. | 2011 | Zhonghua Er Ke Za Zhi | pmid:22336304 |
Wang ZL et al. | [Management of pediatric patients who underwent liver transplantation]. | 2007 | Zhonghua Er Ke Za Zhi | pmid:17880788 |
Wang HY et al. | [Clinical and pathological features of Denys-Drash syndrome: report of 3 cases]. | 2012 | Zhonghua Er Ke Za Zhi | pmid:23302619 |
Nie F et al. | [Post-transplant kidney from C-III donation after cardiac death of children: a clinicopathologic study of 20 cases]. | 2016 | Zhonghua Bing Li Xue Za Zhi | pmid:26879429 |
Xie SP et al. | [Study on the clinical application of wuzhi capsule after renal transplantation]. | 2011 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:22013798 |
Ding CG et al. | [Clinical application and exploration on mechanism of action of Cordyceps sinensis mycelia preparation for renal transplantation recipients]. | 2009 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:20329604 |
Gu HY et al. | [Significance of calcineurin activation and CD40L expression in patients with active lupus nephritis]. | 2005 | Zhongguo Ying Yong Sheng Li Xue Za Zhi | pmid:21162213 |
Tian T et al. | [Effect of tacrolimus on the growth cycle of murine hair follicles]. | 2007 | Zhongguo Yi Xue Ke Xue Yuan Xue Bao | pmid:17536270 |