tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Xie ZQ et al. | [Antipruritic mechanisms of pimecrolimus cream for facial dermatitis in adult women patients]. | 2009 | Zhongguo Yi Xue Ke Xue Yuan Xue Bao | pmid:19317053 |
| Wen J et al. | [Regulatory effects of cyclosporin A and tacrolimus on the immunological gene expressions in renal transplant recipients]. | 2012 | Zhongguo Yi Xue Ke Xue Yuan Xue Bao | pmid:23286399 |
| Xie ZQ and Lan YZ | Effectiveness of pimecrolimus cream for women patients with sensitive skin and its underlying mechanism. | 2012 | Zhongguo Yi Xue Ke Xue Yuan Xue Bao | pmid:22954121 |
| Chen GF et al. | [Peripheral nerve regeneration under immunosuppression]. | 2002 | Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi | pmid:11944523 |
| Xiong G et al. | [Effects of immunosuppressants on proliferation of pheochromocytoma 12 and L929 cells]. | 2007 | Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi | pmid:17694665 |
| Kang H et al. | [Combined immunosuppression of FK506 and RS-61443 in rat limb allotransplantation]. | 2003 | Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi | pmid:12822367 |
| Yu HQ et al. | [Study of tacrolimus intranasal treatment for allergic asthma in mice]. | 2012 | Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi | pmid:23484272 |
| Li Q et al. | [Experimental study of electrophysiologic effects of regenerative nerve fibres affected by control releasing FK506]. | 2010 | Zhongguo Gu Shang | pmid:21254678 |
| Li Y et al. | [Study on the Effect of Immunosuppressive Agent FK506 on Growth and Migration of Lung Cancer Cell]. | 2017 | Zhongguo Fei Ai Za Zhi | pmid:28738959 |
| Zhou Y et al. | [Effect of tacrolimus on growth-associated protein-43 expression in the hippocampus of neonatal rats with hypoxic-ischemic brain damage]. | 2009 | Zhongguo Dang Dai Er Ke Za Zhi | pmid:19149927 |
| Huang WY | [Clinical application and side effects of immunosuppressant]. | 2007 | Zhongguo Dang Dai Er Ke Za Zhi | pmid:17448303 |
| Sun Y et al. | [Total glucosides of peony as adjuvant therapy for prevention of cardiac allograft rejection in rats]. | 2007 | Zhong Xi Yi Jie He Xue Bao | pmid:17854565 |
| Li Y et al. | [Effects of tacrolimus and cyclosporine on albumin secretion in cultured human hepatocyte]. | 2006 | Zhong Nan Da Xue Xue Bao Yi Xue Ban | pmid:16859130 |
| Peng LK et al. | [Slowing progression of chronic allograft nephropathy by conversion from cyclosporin A to tacrolimus]. | 2007 | Zhong Nan Da Xue Xue Bao Yi Xue Ban | pmid:17344588 |
| Li D et al. | [Effect of genetic polymorphism on disposition of calcineurin inhibitors in solid organ transplantation]. | 2010 | Zhong Nan Da Xue Xue Bao Yi Xue Ban | pmid:20871172 |
| Chiu MC | Management strategy for idiopathic nehprotic syndrome in children. | 2008 | Zhong Nan Da Xue Xue Bao Yi Xue Ban | pmid:18245896 |
| Liu Y and Zheng M | [Suppression of Tacrolimus on the expression of MMP-9 in rhHGF-stimulated ECV304 cell line]. | 2004 | Zhejiang Da Xue Xue Bao Yi Xue Ban | pmid:15586415 |
| David M et al. | [Changes in cervix cytology in women with liver transplants treated with immunosuppressive therapy]. | 1993 | Zentralbl Gynakol | pmid:7692689 |
| Lütkes P et al. | [Quality of life following transplantation. The impact ofa new immunosuppressive substance]. | 1999 | Zentralbl Chir | pmid:10209841 |
| Weiner SM | [Combination of tacrolimus and MMF for treatment of proliferative lupus nephritis]. | 2016 | Z Rheumatol | pmid:27259912 |