Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with tacrolimus
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Gómez-Bravo MA et al. | Influence of donor liver CYP3A4*20 loss-of-function genotype on tacrolimus pharmacokinetics in transplanted patients. | 2018 | Pharmacogenet. Genomics | pmid:29256966 |
Motta A et al. | Immunohistopathological characterization and the impact of topical immunomodulatory therapy in oral chronic graft-versus-host disease: A pilot study. | 2018 | Oral Dis | pmid:29197137 |
Leiskau C et al. | Side effects and efficacy of renal sparing immunosuppression in pediatric liver transplantation-A single center matched cohort study. | 2018 | Pediatr Transplant | pmid:29729061 |
Shuker N et al. | Intrapatient Variability in Tacrolimus Exposure Does Not Predict The Development of Cardiac Allograft Vasculopathy After Heart Transplant. | 2018 | Exp Clin Transplant | pmid:28969528 |
Bae SC and Lee YH | Comparative efficacy and tolerability of monotherapy with leflunomide or tacrolimus for the treatment of rheumatoid arthritis: a Bayesian network meta-analysis of randomized controlled trials. | 2018 | Clin. Rheumatol. | pmid:28967035 |
Zhang H et al. | Prediction of Drug-Drug Interaction between Tacrolimus and Principal Ingredients of Wuzhi Capsule in Chinese Healthy Volunteers Using Physiologically-Based Pharmacokinetic Modelling. | 2018 | Basic Clin. Pharmacol. Toxicol. | pmid:28945011 |
Huang F et al. | Pharmacokinetic Interaction between Faldaprevir and Cyclosporine or Tacrolimus in Healthy Volunteers: A Prospective, Open-Label, Fixed-Sequence, Crossover Study. | 2018 | Basic Clin. Pharmacol. Toxicol. | pmid:29427400 |
González-VÃlchez F et al. | Efficacy and Safety of de Novo and Early Use of Extended-release Tacrolimus in Heart Transplantation. | 2018 | Rev Esp Cardiol (Engl Ed) | pmid:28545984 |
Al-Lawati H et al. | Nanomedicine for immunosuppressive therapy: achievements in pre-clinical and clinical research. | 2018 | Expert Opin Drug Deliv | pmid:29261332 |
Park CS et al. | Tetrahydrocurcumin Ameliorates Tacrolimus-Induced Nephrotoxicity Via Inhibiting Apoptosis. | 2018 | Transplant. Proc. | pmid:30401411 |
Thoms S et al. | Tacrolimus inhibits angiogenesis and induces disaggregation of endothelial cells in spheroids - Toxicity testing in a 3D cell culture approach. | 2018 | Toxicol In Vitro | pmid:30048735 |
Kaneko T et al. | Comparison of whole-blood tacrolimus concentrations measured by different immunoassay systems. | 2018 | J. Clin. Lab. Anal. | pmid:29974517 |
Htun YY et al. | CYP3A5*3 Genetic Polymorphism and Tacrolimus Concentration in Myanmar Renal Transplant Patients. | 2018 | Transplant. Proc. | pmid:29731062 |
Hu R et al. | CYP3A5*3 and ABCB1 61A>G Significantly Influence Dose-adjusted Trough Blood Tacrolimus Concentrations in the First Three Months Post-Kidney Transplantation. | 2018 | Basic Clin. Pharmacol. Toxicol. | pmid:29603629 |
Mücke VT et al. | Low Serum Levels of (Dihydro-)Ceramides Reflect Liver Graft Dysfunction in a Real-World Cohort of Patients Post Liver Transplantation. | 2018 | Int J Mol Sci | pmid:29587453 |
Cintra-Cabrera M et al. | Resistant Cytomegalovirus Infection After Renal Transplantation: Literature Review. | 2018 | Transplant. Proc. | pmid:29579856 |
Davidson HE | Shifting Paradigms in Caring for Older Adults. | 2018 | Consult Pharm | pmid:29789044 |
Jouve T et al. | Tailoring tacrolimus therapy in kidney transplantation. | 2018 | Expert Rev Clin Pharmacol | pmid:29779413 |
Pircher C et al. | A rare case of Epstein-Barr virus-associated hepatosplenic smooth muscle tumors after kidney transplantation. | 2018 | Transpl Infect Dis | pmid:29427352 |
Yang Y et al. | Chlormethine Hydrochloride is Not Inferior to Tacrolimus in Treating Steroid-Resistant Nephrotic Syndrome. | 2018 | Kidney Blood Press. Res. | pmid:29402844 |