Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with tacrolimus
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Taormina D et al. | Stability and sorption of FK 506 in 5% dextrose injection and 0.9% sodium chloride injection in glass, polyvinyl chloride, and polyolefin containers. | 1992 | Am J Hosp Pharm | pmid:1373936 |
Tacrolimus introduced for use in liver transplantation. | 1994 | Am J Hosp Pharm | pmid:7524317 | |
Przepiorka D et al. | Blood tacrolimus concentration unchanged by plasmapheresis. | 1994 | Am J Hosp Pharm | pmid:7524318 |
Pezze JL and Whiteman K | Transplantation's newest weapon FK 506. | 1991 | Am J Nurs | pmid:1716857 |
Yang GS et al. | Intratympanic immunosuppressives for prevention of immune-mediated sensorineural hearing loss. | 2000 | Am J Otol | pmid:10912694 |
Tulaci KG et al. | The effect of tacrolimus on facial nerve injury: Histopathological findings in a rabbit model. | Am J Otolaryngol | pmid:27465503 | |
Knott PD et al. | Induction with T-cell receptor antibody leads to long-term laryngeal allograft function. | 2008 Nov-Dec | Am J Otolaryngol | pmid:19144301 |
Laifer SA et al. | Pregnancy after cardiac transplantation. | 1994 | Am J Perinatol | pmid:7519426 |
Lee J et al. | Inpatient rehabilitation challenges in a quadrimembral amputee after bilateral hand transplantation. | 2011 | Am J Phys Med Rehabil | pmid:21765280 |
Reams BD and Palmer SM | Sublingual tacrolimus for immunosuppression in lung transplantation: a potentially important therapeutic option in cystic fibrosis. | 2002 | Am J Respir Med | pmid:14720063 |
Moon BJ et al. | Effect of chronic rhinosinusitis on liver transplant patients. | 2009 Sep-Oct | Am J Rhinol Allergy | pmid:19807981 |
Shin JH et al. | The effect of topical FK506 (tacrolimus) in a mouse model of allergic rhinitis. | 2012 Mar-Apr | Am J Rhinol Allergy | pmid:22487280 |
Vearrier D et al. | Mutism and persistent dysarthria due to tacrolimus-based immunosuppression following allogeneic liver transplantation. | 2011 | Am J Ther | pmid:20535006 |
Sathyan S et al. | Prevention of recurrent episodes of rhabdomyolysis with tacrolimus in a transplant recipient with myopathy. | Am J Ther | pmid:23429166 | |
Liu JY et al. | Tacrolimus Versus Cyclosporine as Primary Immunosuppressant After Renal Transplantation: A Meta-Analysis and Economics Evaluation. | Am J Ther | pmid:25299636 | |
Haroon N et al. | Tacrolimus Toxicity With Minimal Clinical Manifestations: A Case Report and Literature Review. | Am J Ther | pmid:25730156 | |
Nunokawa T et al. | Late-onset scleroderma renal crisis induced by tacrolimus and prednisolone: a case report. | Am J Ther | pmid:22836123 | |
Liu JY et al. | Sirolimus Versus Tacrolimus as Primary Immunosuppressant After Renal Transplantation: A Meta-Analysis and Economics Evaluation. | Am J Ther | pmid:25569597 | |
Cohen SM | Current immunosuppression in liver transplantation. | 2002 Mar-Apr | Am J Ther | pmid:11897926 |
Yousuf Bhat Z et al. | Colchicine-Induced Myopathy in a Tacrolimus-Treated Renal Transplant Recipient: Case Report and Literature Review. | Am J Ther | pmid:24732905 |