tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- J. Pharmacol. Exp. Ther. (1)
- Am. J. Physiol. Renal Physiol. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Garrity ER et al. | Suggested guidelines for the use of tacrolimus in lung-transplant recipients. | 1999 | J. Heart Lung Transplant. | pmid:10328140 |
| Ruzicka T et al. | Tacrolimus: the drug for the turn of the millennium? | 1999 | Arch Dermatol | pmid:10328199 |
| Schmidt RH et al. | Haemolytic-uraemic syndrome after tacrolimus rescue therapy for cortisone-resistant rejection. | 1999 | Nephrol. Dial. Transplant. | pmid:10328486 |
| Kohyama T et al. | A potent immunosuppressant FK506 inhibits IL-8 expression in human eosinophils. | 1999 | Mol. Cell Biol. Res. Commun. | pmid:10329481 |
| Tian J and Karin M | Stimulation of Elk1 transcriptional activity by mitogen-activated protein kinases is negatively regulated by protein phosphatase 2B (calcineurin). | 1999 | J. Biol. Chem. | pmid:10329725 |
| Nakamura H et al. | Induction of autologous graft-versus-host disease after autologous peripheral blood stem cell transplantation. | 1999 | J. Allergy Clin. Immunol. | pmid:10329849 |
| Dresske B et al. | Synergistic impact of "WOFIE" on the immunosuppressive potency of FK 506 in a heterotopic heart transplantation model in the rat. | 1999 | Transplant. Proc. | pmid:10331001 |
| Okamoto H | The CD38-cyclic ADP-ribose signaling system in insulin secretion. | 1999 | Mol. Cell. Biochem. | pmid:10331647 |
| Iwamoto H et al. | Inhibitory effects of FK506 on the development of experimental allergic/immune-mediated blepharoconjunctivitis in Lewis rats by systemic but not by topical administration. | 1999 | Graefes Arch. Clin. Exp. Ophthalmol. | pmid:10333108 |
| Henley SA et al. | Lipids increase after solitary pancreas transplantation. | 1999 | Diabetes Care | pmid:10333952 |
| van den Berg JW et al. | New immunosuppressive drugs and lung transplantation: last or least? | 1999 | Thorax | pmid:10335012 |
| Shirbacheh MV et al. | Pharmacokinetics of intra-arterial delivery of tacrolimus to vascularly isolated rabbit forelimb. | 1999 | J. Pharmacol. Exp. Ther. | pmid:10336506 |
| Gold BG et al. | Immunophilin FK506-binding protein 52 (not FK506-binding protein 12) mediates the neurotrophic action of FK506. | 1999 | J. Pharmacol. Exp. Ther. | pmid:10336507 |
| Steg RE et al. | Cortical blindness and seizures in a patient receiving FK506 after bone marrow transplantation. | 1999 | Bone Marrow Transplant. | pmid:10338054 |
| Ferrand-Drake M et al. | Mitochondrial permeability transition induced DNA-fragmentation in the rat hippocampus following hypoglycemia. | 1999 | Neuroscience | pmid:10338300 |
| Conboy IM et al. | Calcineurin and vacuolar-type H+-ATPase modulate macrophage effector functions. | 1999 | Proc. Natl. Acad. Sci. U.S.A. | pmid:10339586 |
| Ma D and Carlow CK | Molecular characterization of FKBP13 from filarial parasites. | 1999 | Mol. Biochem. Parasitol. | pmid:10340490 |
| Ruddy SB et al. | Design and characterization of a surfactant-enriched tablet formulation for oral delivery of a poorly water-soluble immunosuppressive agent. | 1999 | Int J Pharm | pmid:10341307 |
| Uchio E et al. | Soluble intercellular adhesion molecule-1 (ICAM-1), CD4, CD8 and interleukin-2 receptor in patients with Behçet's disease and Vogt-Koyanagi-Harada's disease. | 1999 Mar-Apr | Clin. Exp. Rheumatol. | pmid:10342043 |
| Moffatt SD et al. | Potential for improved therapeutic index of FK506 in liposomal formulation demonstrated in a mouse cardiac allograft model. | 1999 | Transplantation | pmid:10342309 |