Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with tacrolimus
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Randhawa PS et al. | Clinical significance of renal biopsies showing concurrent acute rejection and tacrolimus-associated tubular vacuolization. | 1999 | Transplantation | pmid:9921801 |
Lee RK et al. | Prostaglandin E2 stimulates amyloid precursor protein gene expression: inhibition by immunosuppressants. | 1999 | J. Neurosci. | pmid:9920657 |
Katznelson S et al. | Clinical aspects of sensitization. | 1997 | Clin Transpl | pmid:9919412 |
Odorico JS et al. | Advances in pancreas transplantation: the University of Wisconsin experience. | 1997 | Clin Transpl | pmid:9919400 |
Gruessner AC and Sutherland DE | Pancreas transplants for United States (US) and non-US cases as reported to the International Pancreas Transplant Registry (IPTR) and to the United Network for Organ Sharing (UNOS). | 1997 | Clin Transpl | pmid:9919390 |
Skuk D et al. | Successful myoblast transplantation in primates depends on appropriate cell delivery and induction of regeneration in the host muscle. | 1999 | Exp. Neurol. | pmid:9918701 |
Bochelen D et al. | Calcineurin inhibitors FK506 and SDZ ASM 981 alleviate the outcome of focal cerebral ischemic/reperfusion injury. | 1999 | J. Pharmacol. Exp. Ther. | pmid:9918571 |
Kobashigawa JA | Advances in immunosuppression for heart transplantation. | 1998 | Adv Card Surg | pmid:9917904 |
Reich K et al. | Topical tacrolimus for pyoderma gangrenosum. | 1998 | Br. J. Dermatol. | pmid:9892935 |
Hamar P et al. | Coinhibition of immune and renin-angiotensin systems reduces the pace of glomerulosclerosis in the rat remnant kidney. | 1999 | J. Am. Soc. Nephrol. | pmid:9892170 |