Yoshimura N et al. |
Effect of a new immunosuppressive agent, FK506, on human lymphocyte responses in vitro. I. Inhibition of expression of alloantigen-activated suppressor cells, as well as induction of alloreactivity. |
1989 |
Transplantation |
pmid:2465592
|
Yoshimura N et al. |
Effect of a new immunosuppressive agent, FK506, on human lymphocyte responses in vitro. II. Inhibition of the production of IL-2 and gamma-IFN, but not B cell-stimulating factor 2. |
1989 |
Transplantation |
pmid:2465593
|
Takabayashi K et al. |
Effect of FK-506, a novel immunosuppressive drug on murine systemic lupus erythematosus. |
1989 |
Clin. Immunol. Immunopathol. |
pmid:2466594
|
Morris RE et al. |
Immunopharmacology of FK-506. |
1989 |
Transplant. Proc. |
pmid:2468201
|
Gschwendt M et al. |
The immunosuppressant FK-506, like cyclosporins and didemnin B, inhibits calmodulin-dependent phosphorylation of the elongation factor 2 in vitro and biological effects of the phorbol ester TPA on mouse skin in vivo. |
1989 |
Immunobiology |
pmid:2471685
|
Fujii Y et al. |
Effect of a novel immunosuppressive agent, FK506, on mitogen-induced inositol phospholipid degradation in rat thymocytes. |
1989 |
Transplantation |
pmid:2472025
|
Tocci MJ et al. |
The immunosuppressant FK506 selectively inhibits expression of early T cell activation genes. |
1989 |
J. Immunol. |
pmid:2472451
|
Beck Y and Akiyama N |
Effect of FK-506 and cyclosporine on human lymphocyte responses in vitro. |
1989 |
Transplant. Proc. |
pmid:2472695
|
Thomson AW |
FK-506--how much potential? |
1989 |
Immunol. Today |
pmid:2473767
|
Ochiai T et al. |
Optimal serum trough levels of FK506 in renal allotransplantation of the beagle dog. |
1989 |
Transplantation |
pmid:2474208
|
Ochiai T et al. |
Effects of combination treatment with FK506 and cyclosporine on survival time and vascular changes in renal-allograft-recipient dogs. |
1989 |
Transplantation |
pmid:2474209
|
Siekierka JJ et al. |
FK-506, a potent novel immunosuppressive agent, binds to a cytosolic protein which is distinct from the cyclosporin A-binding protein, cyclophilin. |
1989 |
J. Immunol. |
pmid:2474605
|
Thomson AW and Woo J |
Immunosuppressive properties of FK-506 and rapamycin. |
1989 |
Lancet |
pmid:2474733
|
Todo S et al. |
Renal transplantation in baboons under FK 506. |
1989 |
Surgery |
pmid:2474865
|
Leonard DK et al. |
Toxicity of FK-506 in human fetal pancreas. |
1989 |
Diabetes |
pmid:2463195
|
Stephen M et al. |
Immunosuppressive activity, lymphocyte subset analysis, and acute toxicity of FK-506 in the rat. A comparative and combination study with cyclosporine. |
1989 |
Transplantation |
pmid:2463701
|
McCauley J et al. |
Treatment of cyclosporin-induced haemolytic uraemic syndrome with FK506. |
1989 Dec 23-30 |
Lancet |
pmid:2481200
|
Collier SJ |
Immunosuppressive drugs. |
1989-1990 |
Curr. Opin. Immunol. |
pmid:2484794
|
Dumont FJ et al. |
Distinct mechanisms of suppression of murine T cell activation by the related macrolides FK-506 and rapamycin. |
1990 |
J. Immunol. |
pmid:1688572
|
Woo J et al. |
Immunosuppressive activity of FK-506 in rats: flow cytometric analysis of lymphocyte populations in blood, spleen and thymus during treatment and following drug withdrawal. |
1990 |
Clin. Exp. Immunol. |
pmid:1689226
|
Dumont FJ et al. |
The immunosuppressive macrolides FK-506 and rapamycin act as reciprocal antagonists in murine T cells. |
1990 |
J. Immunol. |
pmid:1689353
|
Brown Z and Neild GH |
FK-506 and haemolytic uraemic syndrome. |
1990 |
Lancet |
pmid:1689442
|
Thomas J et al. |
The immunosuppressive action of FK506. In vitro induction of allogeneic unresponsiveness in human CTL precursors. |
1990 |
Transplantation |
pmid:1689518
|
Vathsala A et al. |
Analysis of the interactions of immunosuppressive drugs with cyclosporine in inhibiting DNA proliferation. |
1990 |
Transplantation |
pmid:1689520
|
Yamamoto K et al. |
Experimental treatment of autoimmune MRL-lpr/lpr mice with immunosuppressive compound FK506. |
1990 |
Immunology |
pmid:1689694
|
Thomson AW |
Interspecies comparison of the immunosuppressive efficacy and safety of FK 506. |
1990 |
Transplant. Proc. |
pmid:1689883
|
Zeevi A et al. |
Functional differentiation of human cytotoxic T lymphocytes in the presence of FK 506 and CyA. |
1990 |
Transplant. Proc. |
pmid:1689884
|
Morris RE et al. |
Comparative immunopharmacologic effects of FK 506 and CyA in in vivo models of organ transplantation. |
1990 |
Transplant. Proc. |
pmid:1689885
|
Todo S et al. |
Early trials with FK 506 as primary treatment in liver transplantation. |
1990 |
Transplant. Proc. |
pmid:1689886
|
McCauley J et al. |
The effects of FK 506 on renal function after liver transplantation. |
1990 |
Transplant. Proc. |
pmid:1689887
|
Kang Y et al. |
Acute hemodynamic effects of FK 506 during and after orthotopic liver transplantation. |
1990 |
Transplant. Proc. |
pmid:1689889
|
Jain AB et al. |
FK 506 dosage in human organ transplantation. |
1990 |
Transplant. Proc. |
pmid:1689890
|
Demetris AJ et al. |
Pathologic observations in human allograft recipients treated with FK 506. |
1990 |
Transplant. Proc. |
pmid:1689891
|
Shapiro R et al. |
The side effects of FK 506 in humans. |
1990 |
Transplant. Proc. |
pmid:1689892
|
Van Thiel DH et al. |
Gastrointestinal and metabolic problems associated with immunosuppression with either CyA or FK 506 in liver transplantation. |
1990 |
Transplant. Proc. |
pmid:1689893
|
Monden M et al. |
A potent immunosuppressive effect of FK 506 in orthotopic liver transplantation in primates. |
1990 |
Transplant. Proc. |
pmid:1689904
|
Ericzon BG et al. |
Pancreaticoduodenal allotransplantation with FK 506 in the cynomolgus monkey. |
1990 |
Transplant. Proc. |
pmid:1689905
|
Murase N et al. |
Induction of liver, heart, and multivisceral graft acceptance with a short course of FK 506. |
1990 |
Transplant. Proc. |
pmid:1689906
|
Hoffman AL et al. |
The effect of FK 506 on small intestine allotransplantation in the rat. |
1990 |
Transplant. Proc. |
pmid:1689907
|
Lee KK et al. |
Successful orthotopic small bowel transplantation with short-term FK 506 immunosuppressive therapy. |
1990 |
Transplant. Proc. |
pmid:1689908
|
Ueda Y et al. |
Induction of graft acceptance after dog kidney or liver transplantation. |
1990 |
Transplant. Proc. |
pmid:1689909
|
Ohara K et al. |
Toxicologic evaluation of FK 506. |
1990 |
Transplant. Proc. |
pmid:1689910
|
Nalesnik MA et al. |
The effect of FK 506 and CyA on the Lewis rat renal ischemia model. |
1990 |
Transplant. Proc. |
pmid:1689911
|
Francavilla A et al. |
FK 506 as a growth control factor. |
1990 |
Transplant. Proc. |
pmid:1689912
|
Mazzaferro V et al. |
Studies of the hepatotrophic qualities of FK 506 and CyA. |
1990 |
Transplant. Proc. |
pmid:1689913
|
Kay JE et al. |
The mechanism of action of FK 506. |
1990 |
Transplant. Proc. |
pmid:1689914
|
Suzuki N et al. |
Effects of a novel immunosuppressive agent, FK506, on human B cell activation. |
1990 |
Clin. Exp. Immunol. |
pmid:1690097
|
McCauley J et al. |
FK 506 in steroid-resistant focal sclerosing glomerulonephritis of childhood. |
1990 |
Lancet |
pmid:1690326
|
Hoffman AL et al. |
The use of FK-506 for small intestine allotransplantation. Inhibition of acute rejection and prevention of fatal graft-versus-host disease. |
1990 |
Transplantation |
pmid:1690469
|
Woo J et al. |
The influence of FK-506 and low-concentration ciclosporin on human lymphocyte activation antigen expression and blastogenesis: a flow cytometric analysis. |
1990 |
Scand. J. Immunol. |
pmid:1690915
|
Yasunami Y et al. |
FK506 as the sole immunosuppressive agent for prolongation of islet allograft survival in the rat. |
1990 |
Transplantation |
pmid:1691535
|
Metcalfe SM and Richards FM |
Cyclosporine, FK506, and rapamycin. Some effects on early activation events in serum-free, mitogen-stimulated mouse spleen cells. |
1990 |
Transplantation |
pmid:1691537
|
Morimoto T et al. |
Pancreaticoduodenal allotransplantation with FK 506 in the dog. |
1990 |
Transplant. Proc. |
pmid:1691550
|
Yasunami Y et al. |
Characterization of the immunosuppressive activity of FK 506 in rat islet allografts. |
1990 |
Transplant. Proc. |
pmid:1691557
|
Thomson AW |
FK-506 enters the clinic. |
1990 |
Immunol. Today |
pmid:1692221
|
Saitoh Y et al. |
Morphological rejection phases and cytotoxic activity in peripheral blood lymphocytes in canine lung allo-transplantation. |
1990 |
Jpn J Surg |
pmid:1692892
|
Rosen MK et al. |
Inhibition of FKBP rotamase activity by immunosuppressant FK506: twisted amide surrogate. |
1990 |
Science |
pmid:1693013
|
Maruyama M et al. |
Effect of FK506 treatment on allocytolytic T lymphocyte induction in vivo: differential effects of FK506 on L3T4+ and Ly2+ T cells. |
1990 |
Transplantation |
pmid:1696410
|
Standaert RF et al. |
Molecular cloning and overexpression of the human FK506-binding protein FKBP. |
1990 |
Nature |
pmid:1696686
|
Tropschug M et al. |
Isolation and sequence of an FK506-binding protein from N. crassa which catalyses protein folding. |
1990 |
Nature |
pmid:1696687
|
Randall T |
New antirejection drugs anticipated. |
1990 |
JAMA |
pmid:1696999
|
Metcalfe S et al. |
FK 506 and cyclosporine A: early effects on activation and gene induction in mouse spleen cells. |
1990 |
Transplant. Proc. |
pmid:1697107
|
Morris RE et al. |
A study of the contrasting effects of cyclosporine, FK 506, and rapamycin on the suppression of allograft rejection. |
1990 |
Transplant. Proc. |
pmid:1697111
|
Woo J et al. |
Flow cytometric analysis of lymphocyte populations and activation antigen expression in blood and lymphoid tissues of FK 506-treated rats. |
1990 |
Transplant. Proc. |
pmid:1697112
|
Woo J et al. |
Effects of FK 506 and low concentration cyclosporine on human lymphocyte activation antigen expression: a flow cytometric analysis. |
1990 |
Transplant. Proc. |
pmid:1697113
|
Propper DJ et al. |
Low-dose FK 506 inhibits sensitisation after blood transfusions. |
1990 |
Transplant. Proc. |
pmid:1697114
|
Tiebosch A et al. |
Side effects of FK 506 in cynomolgus monkeys: a histopathologic study. |
1990 |
Transplant. Proc. |
pmid:1697115
|
Dammeijer PF et al. |
Combined effect of low-dose FK 506 and cyclosporine A on skin graft survival. |
1990 |
Transplant. Proc. |
pmid:1697116
|
Imai K et al. |
Pancreaticoduodenal allotransplantation with the use of FK 506, cyclosporine, and triple-regimen immunosuppression. |
1990 |
Transplant. Proc. |
pmid:1697117
|
Iga C et al. |
Prolonged survival of small intestinal allograft in the rat with cyclosporine A, FK 506, and 15-deoxyspergualin. |
1990 |
Transplant. Proc. |
pmid:1697118
|
Deguchi K et al. |
[Effects of novel immunosuppressant FK 506 in acute experimental allergic encephalomyelitis]. |
1990 |
No To Shinkei |
pmid:1697182
|
Murase N et al. |
Prevention of spontaneous diabetes in BB rats with FK 506. |
1990 |
Lancet |
pmid:1697397
|
Justice RM et al. |
The detection of proline isomerase activity in FK506-binding protein by two-dimensional 1H NMR exchange spectroscopy. |
1990 |
Biochem. Biophys. Res. Commun. |
pmid:1697463
|
Todo S et al. |
Liver, kidney, and thoracic organ transplantation under FK 506. |
1990 |
Ann. Surg. |
pmid:1697743
|
Sakr MF et al. |
FK 506 ameliorates the hepatic injury associated with ischemia. |
1990 |
Life Sci. |
pmid:1698241
|
Kurasawa K et al. |
The immunosuppressant FK-506 prevents progression of diabetes in nonobese diabetic mice. |
1990 |
Clin. Immunol. Immunopathol. |
pmid:1698584
|
Miyagawa J et al. |
Preventive effect of a new immunosuppressant FK-506 on insulitis and diabetes in non-obese diabetic mice. |
1990 |
Diabetologia |
pmid:1698679
|
Lagodzinski Z et al. |
Effect of FK506 and cyclosporine on primary and secondary skin allograft survival in mice. |
1990 |
Immunology |
pmid:1698713
|
Isai H et al. |
FK 506 and orthotopic liver transplantation in the rat. |
1990 |
Transplant. Proc. |
pmid:1699329
|
Suzuki S et al. |
In vivo 31P nuclear magnetic resonance findings on heterotopically allografted hearts in rats treated with a novel immunosuppressant, FK506. |
1990 |
Heart Vessels |
pmid:1699922
|
Bierer BE et al. |
Probing immunosuppressant action with a nonnatural immunophilin ligand. |
1990 |
Science |
pmid:1700475
|
Murase N et al. |
FK506 suppression of heart and liver allograft rejection. II: The induction of graft acceptance in rats. |
1990 |
Transplantation |
pmid:1700504
|
Burke MD et al. |
Inhibition of the metabolism of cyclosporine by human liver microsomes by FK506. |
1990 |
Transplantation |
pmid:1700507
|
Wicker LS et al. |
Suppression of B cell activation by cyclosporin A, FK506 and rapamycin. |
1990 |
Eur. J. Immunol. |
pmid:1700753
|
Sigal NH et al. |
Observations on the mechanism of action of FK-506. A pharmacologic probe of lymphocyte signal transduction. |
1990 |
Biochem. Pharmacol. |
pmid:1700909
|
Hara S et al. |
The effects of a new immunosuppressive agent, FK506, on the glomerular injury in rats with accelerated nephrotoxic serum glomerulonephritis. |
1990 |
Clin. Immunol. Immunopathol. |
pmid:1700936
|
Murase N et al. |
Effect of FK 506 on spontaneous diabetes in BB rats. |
1990 |
Diabetes |
pmid:1700959
|
Kawashima H and Mochizuki M |
Effects of a new immunosuppressive agent, FK 506, on the efferent limb of the immune responses. |
1990 |
Exp. Eye Res. |
pmid:1701148
|
Siekierka JJ et al. |
The cytosolic-binding protein for the immunosuppressant FK-506 is both a ubiquitous and highly conserved peptidyl-prolyl cis-trans isomerase. |
1990 |
J. Biol. Chem. |
pmid:1701173
|
Johansson A and Möller E |
Evidence that the immunosuppressive effects of FK506 and cyclosporine are identical. |
1990 |
Transplantation |
pmid:1701570
|
Reyes J et al. |
Expressive dysphasia possibly related to FK506 in two liver transplant recipients. |
1990 |
Transplantation |
pmid:1701571
|
Tsuji RF et al. |
Selective immunosuppression of prodigiosin 25-C and FK506 in the murine immune system. |
1990 |
J. Antibiot. |
pmid:1701765
|
Granelli-Piperno A et al. |
The effect of immunosuppressive agents on the induction of nuclear factors that bind to sites on the interleukin 2 promoter. |
1990 |
J. Exp. Med. |
pmid:1701825
|
Lee KK et al. |
Comparison of short-term immunosuppressive therapy with cyclosporine and FK 506 in small-bowel transplantation. |
1990 |
Transplant. Proc. |
pmid:1702239
|
Takai K et al. |
Effects of FK506 on rat thymus: time-course analysis by immunoperoxidase technique and flow cytofluorometry. |
1990 |
Clin. Exp. Immunol. |
pmid:1702372
|
Okubo Y et al. |
FK506, a novel immunosuppressive agent, induces antigen-specific immunotolerance in active Heymann's nephritis and in the autologous phase of Masugi nephritis. |
1990 |
Clin. Exp. Immunol. |
pmid:1702373
|
Arita C et al. |
Inhibition by FK506 of established lesions of collagen-induced arthritis in rats. |
1990 |
Clin. Exp. Immunol. |
pmid:1702374
|
Woo J et al. |
Antigen presentation and HLA-DR expression by FK-506-treated human monocytes. |
1990 |
Immunology |
pmid:1703987
|
Mochizuki M and Kawashima H |
Effects of FK506, 15-deoxyspergualin, and cyclosporine on experimental autoimmune uveoretinitis in the rat. |
1990 |
Autoimmunity |
pmid:1717007
|
Ni M et al. |
FR900506 (FK506) and 15-deoxyspergualin (15-DSG) modulate the kinetics of infiltrating cells in eyes with experimental autoimmune uveoretinitis. |
1990 |
Autoimmunity |
pmid:1717008
|