Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with tacrolimus
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Pirsch JD | Mycophenolate mofetil, tacrolimus, Neoral: from clinical trials to the clinic. | 1998 | Transplant. Proc. | pmid:9723448 |
Xu M et al. | FTY720 compares with FK 506 as rescue therapy in rat heterotopic cardiac transplantation. | 1998 | Transplant. Proc. | pmid:9723447 |
Yonan NA et al. | Tracheal allograft transplantation in rats: the role of immunosuppressive agents in development of obliterative airway disease. | 1998 | Transplant. Proc. | pmid:9723443 |
Perego C et al. | Study of the immunosuppressive effect of SMS 201-995 and its synergic action with FK 506. | 1998 | Transplant. Proc. | pmid:9723434 |
Jonas S et al. | Five-year follow-up of tacrolimus as primary immunosuppressant after liver transplantation. | 1998 | Transplant. Proc. | pmid:9723433 |
Busuttil RW and Holt CD | Tacrolimus is superior to cyclosporine in liver transplantation. | 1998 | Transplant. Proc. | pmid:9723432 |
Vanrenterghem Y | Tacrolimus (FK 506) in kidney transplantation. | 1998 | Transplant. Proc. | pmid:9723431 |
Halloran PF et al. | Calcineurin and the biological effect of cyclosporine and tacrolimus. | 1998 | Transplant. Proc. | pmid:9723430 |
Otto C et al. | Selective immunosuppression with FK 506, anti-IL-2R, and anti-ICAM-1 monoclonal antibodies: contrasting effects after liver and small bowel transplantation in rats. | 1998 | Transplant. Proc. | pmid:9723426 |
Kohnle M et al. | Conversion to tacrolimus in cyclosporin A treated patients with gum hyperplasia. | 1998 | Transplant. Proc. | pmid:9723413 |
Atillasoy E et al. | Cholesterol levels long-term after liver transplant. | 1998 | Transplant. Proc. | pmid:9723387 |
Varghese Z et al. | Oxidizability of low-density lipoproteins from Neoral and tacrolimus-treated renal transplant patients. | 1998 | Transplant. Proc. | pmid:9723384 |
Donadio C et al. | Tubular damage and impairment of renal function in transplanted kidneys. | 1998 | Transplant. Proc. | pmid:9723381 |
Burrows L et al. | Conversion to tacrolimus to ameliorate cyclosporine toxicity in kidney recipients. | 1998 | Transplant. Proc. | pmid:9723378 |
Yoshimura R et al. | Hepatocyte growth factor: a sensitive indicator for CsA-induced nephropathy. | 1998 | Transplant. Proc. | pmid:9723373 |
Curtis JJ | Posttransplant hypertension. | 1998 | Transplant. Proc. | pmid:9723370 |
Falkenstein K and Dunn S | Tacrolimus to cyclosporine microemulsion formulation conversion in the pediatric liver transplant patient. | 1998 | Transplant. Proc. | pmid:9723354 |
Ettenger RB | New immunosuppressive agents in pediatric renal transplantation. | 1998 | Transplant. Proc. | pmid:9723350 |
Berweck S et al. | Clinical use of the euglycemic hyperinsulinemic clamp for diagnosis of tacrolimus-induced insulin resistance after combined pancreas-kidney transplantation. | 1998 | Transplant. Proc. | pmid:9723345 |
Behr TM et al. | Incidence of humoral rejection in heart transplant recipients treated with tacrolimus or cyclosporine A. | 1998 | Transplant. Proc. | pmid:9723333 |