tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- Am. J. Physiol. Renal Physiol. (1)
- Drug Metab. Dispos. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Radziejewski K et al. | Assessment of corneal and conjunctival metaplasia by impression cytology during the treatment of canine keratoconjunctivitis sicca. | 2018 | Acta Vet. Hung. | pmid:29958527 |
| Hasegawa M et al. | Diagnostic criteria, severity classification and guidelines of lichen sclerosus et atrophicus. | 2018 | J. Dermatol. | pmid:29265410 |
| Gómez-Bravo MA et al. | Influence of donor liver CYP3A4*20 loss-of-function genotype on tacrolimus pharmacokinetics in transplanted patients. | 2018 | Pharmacogenet. Genomics | pmid:29256966 |
| Tanaka Y et al. | Cooperation between ER stress and calcineurin signaling contributes to the maintenance of cell wall integrity in Candida glabrata. | 2018 | Fungal Biol | pmid:29248112 |
| Sikma MA et al. | Association of Whole Blood Tacrolimus Concentrations with Kidney Injury in Heart Transplantation Patients. | 2018 | Eur J Drug Metab Pharmacokinet | pmid:29236211 |
| Motta A et al. | Immunohistopathological characterization and the impact of topical immunomodulatory therapy in oral chronic graft-versus-host disease: A pilot study. | 2018 | Oral Dis | pmid:29197137 |
| Jackson Cullison SR and Siegfried EC | Paradoxic eczema in infants after heart transplantation. | 2018 | Pediatr Dermatol | pmid:29194735 |
| Leiskau C et al. | Side effects and efficacy of renal sparing immunosuppression in pediatric liver transplantation-A single center matched cohort study. | 2018 | Pediatr Transplant | pmid:29729061 |
| Cuñetti L et al. | Chronic Pain Treatment With Cannabidiol in Kidney Transplant Patients in Uruguay. | 2018 | Transplant. Proc. | pmid:29579828 |
| Armenta Bautista A et al. | Renal Transplantation in Second-Level Private Hospitals in the State of Mexico. | 2018 | Transplant. Proc. | pmid:29579825 |
| Shuker N et al. | Intrapatient Variability in Tacrolimus Exposure Does Not Predict The Development of Cardiac Allograft Vasculopathy After Heart Transplant. | 2018 | Exp Clin Transplant | pmid:28969528 |
| Bae SC and Lee YH | Comparative efficacy and tolerability of monotherapy with leflunomide or tacrolimus for the treatment of rheumatoid arthritis: a Bayesian network meta-analysis of randomized controlled trials. | 2018 | Clin. Rheumatol. | pmid:28967035 |
| Zhang H et al. | Prediction of Drug-Drug Interaction between Tacrolimus and Principal Ingredients of Wuzhi Capsule in Chinese Healthy Volunteers Using Physiologically-Based Pharmacokinetic Modelling. | 2018 | Basic Clin. Pharmacol. Toxicol. | pmid:28945011 |
| González-VÃlchez F et al. | Efficacy and Safety of de Novo and Early Use of Extended-release Tacrolimus in Heart Transplantation. | 2018 | Rev Esp Cardiol (Engl Ed) | pmid:28545984 |
| Zheng CS et al. | Assessment of the synergic effect of immunomodulation on nerve repair using multiparametric magnetic resonance imaging. | 2018 | Muscle Nerve | pmid:28445921 |
| Al-Lawati H et al. | Nanomedicine for immunosuppressive therapy: achievements in pre-clinical and clinical research. | 2018 | Expert Opin Drug Deliv | pmid:29261332 |
| Ayala E et al. | Haploidentical transplantation as a promising therapy for relapsed hemophagocytic lymphohistiocytosis in an older adult patient. | 2018 | Hematol Oncol Stem Cell Ther | pmid:27352259 |
| Gómez-RÃos GA et al. | Rapid determination of immunosuppressive drug concentrations in whole blood by coated blade spray-tandem mass spectrometry (CBS-MS/MS). | 2018 | Anal. Chim. Acta | pmid:29254576 |
| Park CS et al. | Tetrahydrocurcumin Ameliorates Tacrolimus-Induced Nephrotoxicity Via Inhibiting Apoptosis. | 2018 | Transplant. Proc. | pmid:30401411 |
| Hiramatsu Y et al. | Changes in the blood level, efficacy, and safety of tacrolimus in pregnancy and the lactation period in patients with systemic lupus erythematosus. | 2018 | Lupus | pmid:30394835 |
| Ordóñez-Robles M et al. | Genome-wide transcriptome response of Streptomyces tsukubaensis to N-acetylglucosamine: effect on tacrolimus biosynthesis. | 2018 | Microbiol. Res. | pmid:30384905 |
| Hamano I et al. | Condyloma Acuminata of the Urethra in a Male Renal Transplant Recipient: A Case Report. | 2018 | Transplant. Proc. | pmid:30316397 |
| Thoms S et al. | Tacrolimus inhibits angiogenesis and induces disaggregation of endothelial cells in spheroids - Toxicity testing in a 3D cell culture approach. | 2018 | Toxicol In Vitro | pmid:30048735 |
| Kaneko T et al. | Comparison of whole-blood tacrolimus concentrations measured by different immunoassay systems. | 2018 | J. Clin. Lab. Anal. | pmid:29974517 |
| Saengram W et al. | Extended release versus immediate release tacrolimus in kidney transplant recipients: a systematic review and meta-analysis. | 2018 | Eur. J. Clin. Pharmacol. | pmid:29961086 |
| Tunnicliffe DJ et al. | Immunosuppressive treatment for proliferative lupus nephritis. | 2018 | Cochrane Database Syst Rev | pmid:29957821 |
| Htun YY et al. | CYP3A5*3 Genetic Polymorphism and Tacrolimus Concentration in Myanmar Renal Transplant Patients. | 2018 | Transplant. Proc. | pmid:29731062 |
| Scherrer M et al. | Tacrolimus-induced symmetric drug-related intertriginous and flexural exanthema (SDRIFE). | 2018 | Contact Derm. | pmid:29722025 |
| Del Bello A et al. | High tacrolimus intra-patient variability is associated with graft rejection, and donor-specific antibodies occurrence after liver transplantation. | 2018 | World J. Gastroenterol. | pmid:29713132 |
| Lin G et al. | Evaluation of tacrolimus-related CYP3A5 genotyping in China: Results from the First External Quality Assessment Exercise. | 2018 | J. Clin. Lab. Anal. | pmid:29708622 |
| Hu R et al. | CYP3A5*3 and ABCB1 61A>G Significantly Influence Dose-adjusted Trough Blood Tacrolimus Concentrations in the First Three Months Post-Kidney Transplantation. | 2018 | Basic Clin. Pharmacol. Toxicol. | pmid:29603629 |
| Mücke VT et al. | Low Serum Levels of (Dihydro-)Ceramides Reflect Liver Graft Dysfunction in a Real-World Cohort of Patients Post Liver Transplantation. | 2018 | Int J Mol Sci | pmid:29587453 |
| Cintra-Cabrera M et al. | Resistant Cytomegalovirus Infection After Renal Transplantation: Literature Review. | 2018 | Transplant. Proc. | pmid:29579856 |
| Hong D et al. | [Atopic keratoconjunctivitis: One allergy may mask another. A clinical observation with two types of hypersensitivity reactions: IgE-mediated and non-IgE-mediated]. | 2018 | J Fr Ophtalmol | pmid:29567021 |
| Davidson HE | Shifting Paradigms in Caring for Older Adults. | 2018 | Consult Pharm | pmid:29789044 |
| Jouve T et al. | Tailoring tacrolimus therapy in kidney transplantation. | 2018 | Expert Rev Clin Pharmacol | pmid:29779413 |
| Pircher C et al. | A rare case of Epstein-Barr virus-associated hepatosplenic smooth muscle tumors after kidney transplantation. | 2018 | Transpl Infect Dis | pmid:29427352 |
| Yang Y et al. | Chlormethine Hydrochloride is Not Inferior to Tacrolimus in Treating Steroid-Resistant Nephrotic Syndrome. | 2018 | Kidney Blood Press. Res. | pmid:29402844 |
| Gadby F et al. | [Pulmonary granuloma in an immunodepressed patient]. | 2018 | Rev Mal Respir | pmid:29395568 |
| Onodera M et al. | Tacrolimus Dose Optimization Strategy for Refractory Ulcerative Colitis Based on the Cytochrome P450 3A5 Polymorphism Prediction Using Trough Concentration after 24 Hours. | 2018 | Digestion | pmid:29393157 |
| Liu YC et al. | A Biodegradable, Sustained-Released, Tacrolimus Microfilm Drug Delivery System for the Management of Allergic Conjunctivitis in a Mouse Model. | 2018 | Invest. Ophthalmol. Vis. Sci. | pmid:29392313 |
| Murad A et al. | Primary cutaneous post liver transplant lymphoproliferative disorder (PTLD) successfully treated with radiotherapy. | 2018 | J Dermatolog Treat | pmid:28604230 |
| Rhu J et al. | Clinical Implication of Mycophenolic Acid Trough Concentration Monitoring in Kidney Transplant Patients on a Tacrolimus Triple Maintenance Regimen: A Single-Center Experience. | 2017 | Ann. Transplant. | pmid:29180612 |
| Wang Y et al. | Calcineurin Antagonizes AMPK to Regulate Lipolysis in Caenorhabditis elegans. | 2017 | Molecules | pmid:28672869 |
| Lee D et al. | Age and Early Graft Function Relate With Risk-Benefit Ratio of Allogenic Islet Transplantation Under Antithymocyte Globulin-Mycophenolate Mofetil-Tacrolimus Immune Suppression. | 2017 | Transplantation | pmid:27779572 |
| Eleftheriadis T et al. | In human cell cultures, everolimus is inferior to tacrolimus in inhibiting cellular alloimmunity, but equally effective as regards humoral alloimmunity. | 2017 | Int Urol Nephrol | pmid:28508247 |
| Banovic F et al. | Therapeutic effectiveness of calcineurin inhibitors in canine vesicular cutaneous lupus erythematosus. | 2017 | Vet. Dermatol. | pmid:28439997 |
| Bhari N et al. | Tacrolimus induced dermatophyte infection overlying a plaque morphea. | 2017 | Dermatol Ther | pmid:27502443 |
| Son SY et al. | Comparison of the long-term efficacy and safety of generic Tacrobell with original tacrolimus (Prograf) in kidney transplant recipients. | 2017 | Drug Des Devel Ther | pmid:28138224 |
| Soiffer RJ et al. | Prospective, Randomized, Double-Blind, Phase III Clinical Trial of Anti-T-Lymphocyte Globulin to Assess Impact on Chronic Graft-Versus-Host Disease-Free Survival in Patients Undergoing HLA-Matched Unrelated Myeloablative Hematopoietic Cell Transplantation. | 2017 | J. Clin. Oncol. | pmid:29040031 |