tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- Am. J. Physiol. Renal Physiol. (1)
- Drug Metab. Dispos. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Weichert G and Sauder DN | Efficacy of tacrolimus (FK 506) in idiopathic treatment-resistant pyoderma gangrenosum. | 1998 | J. Am. Acad. Dermatol. | pmid:9777778 |
| Chelmicka-Schorr E et al. | Immunoaugmenting effect of FK 506 on experimental allergic encephalomyelitis in Lewis rats. | 1998 | J. Autoimmun. | pmid:9776710 |
| Fellermann K et al. | Steroid-unresponsive acute attacks of inflammatory bowel disease: immunomodulation by tacrolimus (FK506). | 1998 | Am. J. Gastroenterol. | pmid:9772045 |
| Gómez J et al. | The Bcl-2 gene is differentially regulated by IL-2 and IL-4: role of the transcription factor NF-AT. | 1998 | Oncogene | pmid:9771966 |
| Luo Z et al. | Calcineurin inhibitors and cardiac hypertrophy. | 1998 | Nat. Med. | pmid:9771723 |
| Bennett WM | The nephrotoxicity of new and old immunosuppressive drugs. | 1998 | Ren Fail | pmid:9768435 |
| Lamb ML and Jorgensen WL | Investigations of neurotrophic inhibitors of FK506 binding protein via Monte Carlo simulations. | 1998 | J. Med. Chem. | pmid:9767630 |
| Hauser IA et al. | Therapeutic concentrations of cyclosporine A, but not FK506, increase P-glycoprotein expression in endothelial and renal tubule cells. | 1998 | Kidney Int. | pmid:9767529 |
| Wang JD et al. | Lymphotactin: a key regulator of lymphocyte trafficking during acute graft rejection. | 1998 | Immunology | pmid:9767457 |
| Billaud EM et al. | Evidence for a pharmacokinetic interaction between itraconazole and tacrolimus in organ transplant patients. | 1998 | Br J Clin Pharmacol | pmid:9764970 |
| Karanam BV et al. | Disposition of L-732,531, a potent immunosuppressant, in rats and baboons. | 1998 | Drug Metab. Dispos. | pmid:9763399 |
| Zonneveld IM et al. | Topical tacrolimus is not effective in chronic plaque psoriasis. A pilot study. | 1998 | Arch Dermatol | pmid:9762021 |
| Ohye H et al. | Cellular signaling mechanisms for stimulation of growth hormone secretion and growth hormone primary transcripts by immunosuppressant agents, FK506 and cyclosporin A, in cultured rat pituitary cells. | 1998 Nov-Dec | Neuroimmunomodulation | pmid:9762012 |
| Kliem V and Brunkhorst R | Tacrolimus in kidney transplantation. | 1998 | Contrib Nephrol | pmid:9761977 |
| Schambeck CM et al. | Limit of quantification (functional sensitivity) of the new IMx Tacrolimus II microparticle enzyme immunoassay. | 1998 | Clin. Chem. | pmid:9761266 |
| Ishizuka T et al. | Stem cell factor augments Fc epsilon RI-mediated TNF-alpha production and stimulates MAP kinases via a different pathway in MC/9 mast cells. | 1998 | J. Immunol. | pmid:9759885 |
| Teshima R et al. | Ca2+-ATPase inhibitors and PKC activation synergistically stimulate TNF-alpha production in RBL-2H3 cells. | 1998 | Inflamm. Res. | pmid:9754866 |
| Xu Q et al. | Molecular characterization of a plant FKBP12 that does not mediate action of FK506 and rapamycin. | 1998 | Plant J. | pmid:9753776 |
| Radkowski M et al. | Detection of hepatitis C virus replication in peripheral blood mononuclear cells after orthotopic liver transplantation. | 1998 | Transplantation | pmid:9753352 |
| Woodle ES et al. | Liver transplantation in the first three months of life. | 1998 | Transplantation | pmid:9753340 |