tacrolimus

Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.

Cross Reference

Introduction

To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with tacrolimus?

tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with tacrolimus

MeSH term MeSH ID Detail
Pulmonary Disease, Chronic Obstructive D029424 16 associated lipids
Denys-Drash Syndrome D030321 1 associated lipids
Papillomavirus Infections D030361 4 associated lipids
Hyperuricemia D033461 4 associated lipids
Hypoalbuminemia D034141 1 associated lipids
Mastocytosis, Cutaneous D034701 1 associated lipids
Cholecystolithiasis D041761 2 associated lipids
Intestinal Volvulus D045822 1 associated lipids
Ileus D045823 3 associated lipids
Coproporphyria, Hereditary D046349 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with tacrolimus

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with tacrolimus?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with tacrolimus?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with tacrolimus?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with tacrolimus?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with tacrolimus?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with tacrolimus

Download all related citations
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Authors Title Published Journal PubMed Link
Abu Zaid M et al. Plasma biomarkers of risk for death in a multicenter phase 3 trial with uniform transplant characteristics post-allogeneic HCT. 2017 Blood pmid:27827824
Suetsugu K et al. Analysis of the variable factors influencing tacrolimus blood concentration during the switch from continuous intravenous infusion to oral administration after allogeneic hematopoietic stem cell transplantation. 2017 Int. J. Hematol. pmid:27822915
Saito R et al. Two cases of eczematous drug eruption caused by oral tacrolimus administration. 2017 Contact Derm. pmid:28703346
Martial LC et al. Dried Blood Spot Sampling for Tacrolimus and Mycophenolic Acid in Children: Analytical and Clinical Validation. 2017 Ther Drug Monit pmid:28700522
Shahid S et al. Chronic hepatitis in the transplant patient. 2017 Br J Hosp Med (Lond) pmid:28692371
Lee JE et al. A Case of Rheumatoid Vasculitis Involving Hepatic Artery in Early Rheumatoid Arthritis. 2017 J. Korean Med. Sci. pmid:28581281
Riva N et al. Pharmacoepidemiology of tacrolimus in pediatric liver transplantation. 2017 Pediatr Transplant pmid:28574195
Wu H et al. Novel self-assembled tacrolimus nanoparticles cross-linking thermosensitive hydrogels for local rheumatoid arthritis therapy. 2017 Colloids Surf B Biointerfaces pmid:27736727
Filipec Kanizaj T and Mijic M Inflammatory bowel disease in liver transplanted patients. 2017 World J. Gastroenterol. pmid:28566881
Liang Q et al. The efficacy and safety of tacrolimus monotherapy in adult-onset nephrotic syndrome caused by idiopathic membranous nephropathy. 2017 Ren Fail pmid:28562168
Chen B et al. Population pharmacokinetics and Bayesian estimation of tacrolimus exposure in Chinese liver transplant patients. 2017 J Clin Pharm Ther pmid:28833329
Damon C et al. Predictive Modeling of Tacrolimus Dose Requirement Based on High-Throughput Genetic Screening. 2017 Am. J. Transplant. pmid:27597269
Donati M et al. Resolution of Benign and Malignant Sebaceous Neoplasms, in a Renal Transplant Patient Treated With Everolimus. 2017 Exp Clin Transplant pmid:25924010
Costa JS et al. Polyomavirus Nephropathy: Ten-Year Experience. 2017 Transplant. Proc. pmid:28457399
Ren S et al. Comparative effectiveness and tolerance of immunosuppressive treatments for idiopathic membranous nephropathy: A network meta-analysis. 2017 PLoS ONE pmid:28898290
Egeland EJ et al. High Tacrolimus Clearance Is a Risk Factor for Acute Rejection in the Early Phase After Renal Transplantation. 2017 Transplantation pmid:28452920
Karchin JM et al. Small Molecule-Induced Domain Swapping as a Mechanism for Controlling Protein Function and Assembly. 2017 Sci Rep pmid:28287617
Mizuno H et al. Extranodal NK/T cell lymphoma in a living donor liver transplant recipient. 2017 Ann. Hematol. pmid:28280996
Forker R et al. [A 20-year-old woman with ulcerative colitis and acute liver failure]. 2017 Internist (Berl) pmid:28271269
Ciftci HS et al. Influence of Proton Pump Inhibitors on Mycophenolic Acid Pharmacokinetics in Patients With Renal Transplantation and the Relationship With Cytochrome 2C19 Gene Polymorphism. 2017 Transplant. Proc. pmid:28340819
Aktürk S et al. Average Tacrolimus Trough Level in the First Month After Transplantation May Predict Acute Rejection. 2017 Transplant. Proc. pmid:28340806
Rodrigues N et al. Serum Magnesium and Related Factors in Long-Term Renal Transplant Recipients: An Observational Study. 2017 Transplant. Proc. pmid:28457398
Mashayekhi S et al. The treatment of vulval lichen sclerosus in prepubertal girls: a critically appraised topic. 2017 Br. J. Dermatol. pmid:28244087
Guttman-Yassky E et al. Molecular signatures order the potency of topically applied anti-inflammatory drugs in patients with atopic dermatitis. 2017 J. Allergy Clin. Immunol. pmid:28238742
Takagi K et al. Syndrome of Inappropriate Antidiuretic Hormone Secretion Following Liver Transplantation. 2017 Acta Med. Okayama pmid:28238015
Riva N et al. Therapeutic monitoring of pediatric transplant patients with conversion to generic tacrolimus. 2017 Farm Hosp pmid:28236795
Sahutoglu T et al. Tac-MMF Versus CsA-MMF/CsA-AZA-Based Regimens in Development of De Novo Complement-Binding Anti-HLA Antibodies After Kidney Transplantation. 2017 Transplant. Proc. pmid:28340811
Rebora A Tacrolimus and oral lichen planus: the question remains. 2017 J Eur Acad Dermatol Venereol pmid:27324047
Kanai T et al. Adequate tacrolimus concentration for myasthenia gravis treatment. 2017 Eur. J. Neurol. pmid:28102047
Sarier M et al. HPV type 45-positive condyloma acuminata of the bladder in a renal transplant recipient. 2017 Transpl Infect Dis pmid:28100036
Fan B et al. Prograf produces more benefits for CYP3A5 low expression patients in early stage after kidney transplantation. 2017 Biomed. Pharmacother. pmid:28157649
Hanchanale P et al. Nocardia liver abscess post liver transplantation-A rare presentation. 2017 Transpl Infect Dis pmid:28150374
Størset E et al. The CYP3A biomarker 4β-hydroxycholesterol does not improve tacrolimus dose predictions early after kidney transplantation. 2017 Br J Clin Pharmacol pmid:28146606
do Valle IB et al. Green Teeth in the Primary and Permanent Dentition. 2017 J. Pediatr. pmid:28965735
Juvvadi PR et al. Calcineurin in fungal virulence and drug resistance: Prospects for harnessing targeted inhibition of calcineurin for an antifungal therapeutic approach. 2017 Virulence pmid:27325145
Pensi D et al. First UHPLC-MS/MS method coupled with automated online SPE for quantification both of tacrolimus and everolimus in peripheral blood mononuclear cells and its application on samples from co-treated pediatric patients. 2017 J Mass Spectrom pmid:28098395
Lewis K et al. Autoimmune enteropathy and hepatitis in pediatric heart transplant recipient. 2017 Pediatr Transplant pmid:28097735
Shimizu K Development of New Liposome Targeting Strategies for Application of Disease Therapies. 2017 Yakugaku Zasshi pmid:28049894
Cukor D et al. A Pilot Randomized Controlled Trial to Promote Immunosuppressant Adherence in Adult Kidney Transplant Recipients. 2017 Nephron pmid:28049201
Calvo PL et al. Donor CYP3A5 genotype influences tacrolimus disposition on the first day after paediatric liver transplantation. 2017 Br J Clin Pharmacol pmid:28044353
Baskiran A et al. Pregnancy After Liver Transplantation: Risks and Outcomes. 2017 Transplant. Proc. pmid:28923640
Shi G et al. Variation of CD4CD25Foxp3 Regulatory T Cells and Th17 Cells in the Peripheral Blood of Human Liver Allograft Patients With Long-term Survival. 2017 Transplant. Proc. pmid:28923634
Wang L et al. Efficacy and safety of tacrolimus for myasthenia gravis: a systematic review and meta-analysis. 2017 J. Neurol. pmid:28921038
Hu Y et al. FK506 suppresses hypoxia‑induced inflammation and protects tight junction function via the CaN‑NFATc1 signaling pathway in retinal microvascular epithelial cells. 2017 Mol Med Rep pmid:28901449
Weininger U et al. Dynamics of Aromatic Side Chains in the Active Site of FKBP12. 2017 Biochemistry pmid:27936610
Hosoi K et al. Prolonged tacrolimus for pediatric gastrointestinal disorder: Double-edged sword? 2017 Pediatr Int pmid:27935231
Maldonado AQ et al. Prevalence of CYP3A5 Genomic Variances and Their Impact on Tacrolimus Dosing Requirements among Kidney Transplant Recipients in Eastern North Carolina. 2017 Pharmacotherapy pmid:28605053
Esquirol A et al. Single-agent GvHD prophylaxis with tacrolimus after post-transplant high-dose cyclophosphamide is a valid option for haploidentical transplantation in adults with hematological malignancies. 2017 Bone Marrow Transplant. pmid:28604667
Zhang W et al. Isoglycyrrhizinate Magnesium Enhances Hepatoprotective Effect of FK506 on Ischemia-Reperfusion Injury Through HMGB1 Inhibition in a Rat Model of Liver Transplantation. 2017 Transplantation pmid:28885495
Burbulla LF et al. Dopamine oxidation mediates mitochondrial and lysosomal dysfunction in Parkinson's disease. 2017 Science pmid:28882997