tacrolimus

Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.

Cross Reference

Introduction

To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with tacrolimus?

tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with tacrolimus

MeSH term MeSH ID Detail
Liver Cirrhosis, Alcoholic D008104 17 associated lipids
Liver Cirrhosis, Biliary D008105 12 associated lipids
Liver Diseases D008107 31 associated lipids
Long QT Syndrome D008133 10 associated lipids
Lung Abscess D008169 1 associated lipids
Lung Diseases D008171 37 associated lipids
Lung Neoplasms D008175 171 associated lipids
Lupus Erythematosus, Cutaneous D008178 2 associated lipids
Lupus Erythematosus, Discoid D008179 1 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Lupus Nephritis D008181 8 associated lipids
Lymphocele D008210 1 associated lipids
Lymphocytic Choriomeningitis D008216 1 associated lipids
Lymphoma D008223 18 associated lipids
Lymphomatoid Granulomatosis D008230 2 associated lipids
Lymphoproliferative Disorders D008232 7 associated lipids
Malacoplakia D008287 1 associated lipids
Malocclusion, Angle Class II D008312 1 associated lipids
Mastocytosis D008415 5 associated lipids
Mediastinal Diseases D008477 1 associated lipids
Mediastinal Emphysema D008478 1 associated lipids
Mediastinitis D008480 2 associated lipids
Megacolon, Toxic D008532 1 associated lipids
Melanoma D008545 69 associated lipids
Memory Disorders D008569 33 associated lipids
Meningococcal Infections D008589 3 associated lipids
Meningoencephalitis D008590 4 associated lipids
Metaplasia D008679 7 associated lipids
Mite Infestations D008924 1 associated lipids
Molluscum Contagiosum D008976 2 associated lipids
Mouth Diseases D009059 5 associated lipids
Moyamoya Disease D009072 1 associated lipids
Multiple Myeloma D009101 13 associated lipids
Muscular Dystrophies D009136 10 associated lipids
Mutism D009155 1 associated lipids
Myasthenia Gravis D009157 5 associated lipids
Mycobacterium Infections D009164 7 associated lipids
Mycobacterium Infections, Nontuberculous D009165 8 associated lipids
Mycoses D009181 18 associated lipids
Myelitis D009187 1 associated lipids
Myxedema D009230 2 associated lipids
Nail Diseases D009260 2 associated lipids
Necrobiosis Lipoidica D009335 2 associated lipids
Neoplasm Invasiveness D009361 23 associated lipids
Neoplasm Recurrence, Local D009364 5 associated lipids
Neovascularization, Pathologic D009389 39 associated lipids
Nephritis D009393 19 associated lipids
Nephritis, Hereditary D009394 1 associated lipids
Nephritis, Interstitial D009395 10 associated lipids
Nephrotic Syndrome D009404 11 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with tacrolimus

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with tacrolimus?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with tacrolimus?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with tacrolimus?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with tacrolimus?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with tacrolimus?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with tacrolimus

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Per page 10 20 50 100 | Total 15051
Authors Title Published Journal PubMed Link
Moncourier M et al. [Granulomatous periocular eruption]. Ann Dermatol Venereol pmid:28410769
Kotowski M et al. The Importance of New Generation Sequencing (NGS) HLA Typing in Renal Transplantation-Preliminary Report. Transplant. Proc. pmid:29937294
Gupta S and Brennan DC Pneumococcal 13-Valent Conjugate Vaccine (Prevnar 13)-Associated Immune Thrombocytopenic Purpura in a Renal Transplant Recipient: A Case Report. Transplant. Proc. pmid:26915880
Stringa P et al. Pretreatment Combination Reduces Remote Organ Damage Secondary to Intestinal Reperfusion Injury in Mice: Follow-up Study. Transplant. Proc. pmid:26915870
Soda M et al. Association Between Tacrolimus Pharmacokinetics and Cytochrome P450 3A5 and Multidrug Resistance Protein 1 Exon 21 Polymorphisms. Transplant. Proc. pmid:28736028
Mac Guad R et al. Effects of CYP3A5 Genetic Polymorphism on the Pharmacokinetics of Tacrolimus in Renal Transplant Recipients. Transplant. Proc. pmid:26915847
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Wei KC and Lai PC Combination of everolimus and tacrolimus: a potentially effective regimen for recalcitrant psoriasis. Dermatol Ther pmid:25285355
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Yang A and Wang B Sirolimus versus tacrolimus in kidney transplant recipients receiving mycophenolate mofetil and steroids: focus on acute rejection, patient and graft survival. Am J Ther pmid:23921809
Mackesy MM et al. Immunosuppressant-induced acneiform eruption of the breast. Breast J pmid:25229395
Pan W et al. Combination of hydrotropic nicotinamide with nanoparticles for enhancing tacrolimus percutaneous delivery. Int J Nanomedicine pmid:27578973
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Sahu MK et al. High blood tacrolimus and hyperkalemia in a heart transplant patient. Ann Card Anaesth pmid:28393798
Lasa J and Olivera P EFFICACY OF TACROLIMUS FOR INDUCTION OF REMISSION IN PATIENTS WITH MODERATE-TO-SEVERE ULCERATIVE COLITIS: A SYSTEMATIC REVIEW AND META-ANALYSIS. Arq Gastroenterol pmid:28327826
Liu JY et al. Tacrolimus Versus Cyclosporine as Primary Immunosuppressant After Renal Transplantation: A Meta-Analysis and Economics Evaluation. Am J Ther pmid:25299636
Lima RS et al. Granuloma faciale: a good therapeutic response with the use of topical tacrolimus. An Bras Dermatol pmid:26560220
Haroon N et al. Tacrolimus Toxicity With Minimal Clinical Manifestations: A Case Report and Literature Review. Am J Ther pmid:25730156
Zmonarski S et al. Expression of PBMC TLR4 in Renal Graft Recipients Who Experienced Delayed Graft Function Reflects Dynamic Balance Between Blood and Tissue Compartments and Helps Select a Problematic Patient. Transplant. Proc. pmid:30056893
Kubiça TF et al. Antifungal activities of tacrolimus in combination with antifungal agents against fluconazole-susceptible and fluconazole-resistant Trichosporon asahii isolates. Braz J Infect Dis pmid:27697432
Zulim LFDC et al. Comparison of the efficacy of 0.03% tacrolimus eye drops diluted in olive oil and linseed oil for the treatment of keratoconjunctivitis sicca in dogs. Arq Bras Oftalmol pmid:29995121
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Yamamoto T et al. Efficacy of Eculizumab Therapy for Atypical Hemolytic Uremic Syndrome Recurrence and Antibody-Mediated Rejection Progress After Renal Transplantation With Preformed Donor-Specific Antibodies: Case Report. Transplant. Proc. pmid:28104125
Dogra PM et al. Tacrolimus for treatment of toxic epidermal necrolysis. Indian J Dermatol Venereol Leprol pmid:26515857
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Kabuto M et al. Annular lupus erythematosus profundus. Eur J Dermatol pmid:25115404
Zhang J et al. Chemotherapy for De Novo Gastric Adenocarcinoma After Deceased Orthotopic Liver Transplantation: A Case Report. Transplant. Proc. pmid:28104131
Ishida S et al. Calcineurin Inhibitor-Induced Pain Syndrome in ABO-Incompatible Living Kidney Transplantation: A Case Report. Transplant. Proc. pmid:28104127
pmid:8986461
Forns X et al. Efficacy of telaprevir-based therapy in stable liver transplant patients with chronic genotype 1 hepatitis C. Ann Hepatol pmid:27236150
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pmid:21079467
Ito T et al. Therapeutic Effect of Sirolimus for Lymphangioleiomyomatosis Remaining in the Abdominopelvic Region After Lung Transplantation: A Case Report. Transplant. Proc. pmid:26915883
Norero B et al.  Conversion to mycophenolate mofetil monotherapy in liver recipients: Calcineurin inhibitor levels are key. Ann Hepatol pmid:28051798
Hirata Y et al. Antibody Drug Treatment for Steroid-Resistant Rejection After Pediatric Living Donor Liver Transplantation: A Single-Center Experience. Transplant. Proc. pmid:29407332
Back JH et al. Antiproteinuric Effects of Green Tea Extract on Tacrolimus-Induced Nephrotoxicity in Mice. Transplant. Proc. pmid:26293093
Shingaki S et al. Graft-versus-host Disease-free, Relapse-free Survival After HLA-identical Sibling Peripheral Blood Stem Cell Transplantation With Tacrolimus-based Graft-versus-host Disease Prophylaxis in Japanese Patients. Transplant. Proc. pmid:29407317
Kim SH et al. Outcomes of Early Conversion From Prograf to Generic Tacrolimus in Adult Living Donor Liver Transplant Recipients. Transplant. Proc. pmid:26293073
Manzia TM et al. Ab initio Everolimus-based Versus Standard Calcineurin Inhibitor Immunosuppression Regimen in Liver Transplant Recipients. Transplant. Proc. pmid:29407305
Falconer SJ et al. Early or Late Conversion From Tac-BD to Tac-BD in Renal Transplantation: When is the Right Time? Transplant. Proc. pmid:26293044
Clark K et al. Oxidative Stress Induces Disruption of the Axon Initial Segment. ASN Neuro pmid:29228786
Byun JW et al. A successful helium-neon laser and topical tacrolimus combination therapy in one child with vitiligo. Dermatol Ther pmid:26278617
Yousuf Bhat Z et al. Colchicine-Induced Myopathy in a Tacrolimus-Treated Renal Transplant Recipient: Case Report and Literature Review. Am J Ther pmid:24732905
Regueiro-García A et al. Haploidentical stem cell transplantation in a boy with chronic granulomatous disease. Allergol Immunopathol (Madr) pmid:29373243
Lythgoe M and Abraham S Tacrolimus: an effective treatment in refractory psoriatic arthritis following biologic failure. Clin. Exp. Rheumatol. pmid:26211753
Leon L et al. Successfull Simultaneous Pancreas Kidney transplantation in a patient with Congenital Partial Lipodystrophy. Nefrologia pmid:27006329