tacrolimus

Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.

Cross Reference

Introduction

To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with tacrolimus?

tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with tacrolimus

MeSH term MeSH ID Detail
Dyspnea D004417 10 associated lipids
Hemophilia A D006467 10 associated lipids
Muscular Dystrophies D009136 10 associated lipids
Alveolar Bone Loss D016301 10 associated lipids
Glycosuria D006029 10 associated lipids
Respiratory Insufficiency D012131 10 associated lipids
Fatigue D005221 10 associated lipids
Dermatitis, Seborrheic D012628 10 associated lipids
Long QT Syndrome D008133 10 associated lipids
Neuromuscular Diseases D009468 10 associated lipids
Vision Disorders D014786 10 associated lipids
Dry Eye Syndromes D015352 10 associated lipids
Nephritis, Interstitial D009395 10 associated lipids
Shock, Septic D012772 11 associated lipids
Nephrotic Syndrome D009404 11 associated lipids
Dehydration D003681 11 associated lipids
Influenza, Human D007251 11 associated lipids
Urinary Tract Infections D014552 11 associated lipids
Exanthema D005076 11 associated lipids
Hyperpigmentation D017495 11 associated lipids
Lymphoma, T-Cell D016399 11 associated lipids
Uveitis, Anterior D014606 11 associated lipids
Candidiasis, Oral D002180 11 associated lipids
Graft Occlusion, Vascular D006083 11 associated lipids
Liver Failure, Acute D017114 11 associated lipids
Shock D012769 11 associated lipids
Hyperbilirubinemia D006932 11 associated lipids
Scalp Dermatoses D012536 11 associated lipids
Thinness D013851 11 associated lipids
Duodenal Ulcer D004381 12 associated lipids
Keloid D007627 12 associated lipids
Hypertension, Portal D006975 12 associated lipids
Arterial Occlusive Diseases D001157 12 associated lipids
Retinoblastoma D012175 12 associated lipids
Listeriosis D008088 12 associated lipids
Osteoporosis D010024 12 associated lipids
Liver Cirrhosis, Biliary D008105 12 associated lipids
Abortion, Spontaneous D000022 12 associated lipids
Skin Neoplasms D012878 12 associated lipids
Eye Diseases D005128 12 associated lipids
Crohn Disease D003424 12 associated lipids
Hepatitis C, Chronic D019698 12 associated lipids
Hypertrophy, Left Ventricular D017379 12 associated lipids
Osteoarthritis, Knee D020370 13 associated lipids
Critical Illness D016638 13 associated lipids
Sarcoidosis D012507 13 associated lipids
Hypoglycemia D007003 13 associated lipids
Urticaria D014581 13 associated lipids
Hypercalcemia D006934 13 associated lipids
Biliary Fistula D001658 13 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with tacrolimus

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with tacrolimus?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with tacrolimus?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with tacrolimus?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with tacrolimus?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with tacrolimus?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with tacrolimus

Download all related citations
Per page 10 20 50 100 | Total 15051
Authors Title Published Journal PubMed Link
Drake M et al. The immunosuppressant FK506 ameliorates ischaemic damage in the rat brain. 1996 Acta Physiol. Scand. pmid:8899062
Ibarra FR et al. Intracellular sodium modulates the state of protein kinase C phosphorylation of rat proximal tubule Na+,K+-ATPase. 2002 Acta Physiol. Scand. pmid:12028137
Folwarczna J et al. Effect of low-dose tacrolimus coadministered with raloxifene on the skeletal system in male rats. 2009 Mar-Apr Acta Pol Pharm pmid:19719057
Turło J et al. Submerged cultivation of Streptomyces tsukubaensis in media composed of waste products of food industry. 2006 Sep-Oct Acta Pol Pharm pmid:17357618
Kaczmarczyk-Sedlak I et al. Raloxifene does not affect the changes in bone histomorphometric parameters induced by low dose tacrolimus in male rats. 2006 Jul-Aug Acta Pol Pharm pmid:17203868
Wartenberg KE et al. Transient diffusion-weighted imaging changes in a patient with reversible leukoencephalopathy syndrome. 2004 Acta Radiol pmid:15587428
Radziejewski K et al. Assessment of corneal and conjunctival metaplasia by impression cytology during the treatment of canine keratoconjunctivitis sicca. 2018 Acta Vet. Hung. pmid:29958527
Radziejewski K and Balicki I Comparative clinical evaluation of tacrolimus and cyclosporine eye drops for the treatment of canine keratoconjunctivitis sicca. 2016 Acta Vet. Hung. pmid:27653428
Kageyama S et al. Augmentation of natural killer cell activity induced by cytomegalovirus infection in mice treated with FK506. 1997 Acta Virol. pmid:9391652
Martí N et al. [Generalized eruption in a child]. 2012 Actas Dermosifiliogr pmid:22169091
Ormaechea-Pérez N et al. Superficial granulomatous pyoderma. Report of 2 cases treated with topical tacrolimus. 2013 Actas Dermosifiliogr pmid:23933249
García-Rabasco AE et al. [Pyoderma gangrenosum associated with hidradenitis suppurativa: a case report and review of the literature]. 2010 Actas Dermosifiliogr pmid:20965015
Blasco-Morente G et al. Long-Standing Presternal Plaque. 2015 Actas Dermosifiliogr pmid:25917959
Turrión-Merino L et al. A Case Series of 4 Patients With Peristomal Pyoderma Gangrenosum: Review of Risk Factors and Treatment Response. 2016 Actas Dermosifiliogr pmid:26626501
Salgüero Fernández I et al. Rapidly progressive infiltrated plaques in a transplant recipient. 2017 Actas Dermosifiliogr pmid:27677210
Varela-Veiga A et al. Long-standing Papules on the Scrotum. 2017 Actas Dermosifiliogr pmid:27328825
Alomar A et al. [Tacrolimus in diseases other than atopic dermatitis]. 2008 Actas Dermosifiliogr pmid:18346427
Esteve-Martínez A et al. [Treatment-resistant adult atopic dermatitis]. 2011 Actas Dermosifiliogr pmid:21820642
Pérez-López I et al. Koebner phenomenon in a patient with lichen sclerosus following a jellyfish sting: an exceptional morphology. 2015 Actas Dermosifiliogr pmid:25597413
Ojeda T et al. [Ulcerative lichen planus of the sole treated with tacrolimus, 0.1%]. 2011 Actas Dermosifiliogr pmid:21345398