Galat A et al. |
A rapamycin-selective 25-kDa immunophilin. |
1992 |
Biochemistry |
pmid:1371698
|
Hanawa H et al. |
An immunosuppressant compound, FK-506, prevents the progression of autoimmune myocarditis in rats. |
1992 |
Clin. Immunol. Immunopathol. |
pmid:1371730
|
Hiraoka Y et al. |
The effects of FK-506, a novel and potent immunosuppressant, upon murine Coxsackievirus B3 myocarditis. |
1992 |
J. Pharmacol. Exp. Ther. |
pmid:1372051
|
Chen TS et al. |
Microbial transformation of immunosuppressive compounds. I. Desmethylation of FK506 and immunomycin (FR 900520) by Actinoplanes sp. ATCC 53771. |
1992 |
J. Antibiot. |
pmid:1372307
|
Morisaki M and Arai T |
Identity of immunosuppressant FR-900520 with ascomycin. |
1992 |
J. Antibiot. |
pmid:1372308
|
Doi R et al. |
Effects of FK506 on exocrine pancreas in rats. |
1992 |
Pancreas |
pmid:1372739
|
Furukawa H et al. |
The effect of bile duct ligation and bile diversion on FK506 pharmacokinetics in dogs. |
1992 |
Transplantation |
pmid:1373531
|
Sakr M et al. |
Cytomegalovirus infection of the upper gastrointestinal tract following liver transplantation--incidence, location, and severity in cyclosporine- and FK506-treated patients. |
1992 |
Transplantation |
pmid:1373535
|
Hirano Y et al. |
Morphological and functional changes of islets of Langerhans in FK506-treated rats. |
1992 |
Transplantation |
pmid:1373536
|
Kawaguchi S |
[Effects of FK506 on aminonucleoside-induced nephrotic rats]. |
1992 |
Nihon Jinzo Gakkai Shi |
pmid:1375300
|
Sigal NH and Dumont FJ |
Cyclosporin A, FK-506, and rapamycin: pharmacologic probes of lymphocyte signal transduction. |
1992 |
Annu. Rev. Immunol. |
pmid:1375473
|
Chen TS et al. |
Microbial transformation of immunosuppressive compounds. II. Specific desmethylation of 13-methoxy group of FK 506 and FR 900520 by an unidentified Actinomycete ATCC 53828 [corrected]. |
1992 |
J. Antibiot. |
pmid:1375593
|
Meingassner JG and Stütz A |
Immunosuppressive macrolides of the type FK 506: a novel class of topical agents for treatment of skin diseases? |
1992 |
J. Invest. Dermatol. |
pmid:1375617
|
Schneck FX et al. |
Pediatric renal transplantation under FK-506 immunosuppression. |
1992 |
J. Urol. |
pmid:1375663
|
Connelly PR and Thomson JA |
Heat capacity changes and hydrophobic interactions in the binding of FK506 and rapamycin to the FK506 binding protein. |
1992 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:1375751
|
Lancaster JR et al. |
EPR detection of heme and nonheme iron-containing protein nitrosylation by nitric oxide during rejection of rat heart allograft. |
1992 |
J. Biol. Chem. |
pmid:1375934
|
Ohtsuka S et al. |
The effect of short-term FK 506 therapy on pancreas transplantation using the cuff technique in rats. |
1992 |
Transplant. Proc. |
pmid:1376532
|
Demetris AJ et al. |
Donor dendritic cells after liver and heart allotransplantation under short-term immunosuppression. |
1992 |
Lancet |
pmid:1376851
|
Ichihashi T et al. |
Haemolytic uraemic syndrome during FK506 therapy. |
1992 |
Lancet |
pmid:1376852
|
O'Keefe SJ et al. |
FK-506- and CsA-sensitive activation of the interleukin-2 promoter by calcineurin. |
1992 |
Nature |
pmid:1377361
|
Clipstone NA and Crabtree GR |
Identification of calcineurin as a key signalling enzyme in T-lymphocyte activation. |
1992 |
Nature |
pmid:1377362
|
Hasegawa S et al. |
Combination use of suboptimal dose of FK 506 and cyclosporine in canine lung transplantation. |
1992 |
J. Thorac. Cardiovasc. Surg. |
pmid:1279319
|
Peattie DA et al. |
Expression and characterization of human FKBP52, an immunophilin that associates with the 90-kDa heat shock protein and is a component of steroid receptor complexes. |
1992 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:1279700
|
Lhoëst G et al. |
Isolation and mass spectrometric identification of two metabolites of FK 506 from rat liver microsomal incubation media. |
1992 |
Pharm Acta Helv |
pmid:1279730
|
Bergstrand H et al. |
Modulation of neutrophil superoxide generation by inhibitors of protein kinase C, calmodulin, diacylglycerol and myosin light chain kinases, and peptidyl prolyl cis-trans isomerase. |
1992 |
J. Pharmacol. Exp. Ther. |
pmid:1281879
|
DiLella AG et al. |
Chromosomal band assignments of the genes encoding human FKBP12 and FKBP13. |
1992 |
Biochem. Biophys. Res. Commun. |
pmid:1281998
|
Sawada M et al. |
Down regulation of CD4 expression in cultured microglia by immunosuppressants and lipopolysaccharide. |
1992 |
Biochem. Biophys. Res. Commun. |
pmid:1282000
|
Minoda M et al. |
Effects of gamma-interferon and FK506 on resting B cell proliferation of New Zealand black/white F1 mice. |
1992 |
Microbiol. Immunol. |
pmid:1282197
|
Min DI et al. |
Visual compatibility of tacrolimus with commonly used drugs during simulated Y-site injection. |
1992 |
Am J Hosp Pharm |
pmid:1282779
|
Mochizuki M |
[Immunotherapy in ocular diseases]. |
1992 |
Nippon Ganka Gakkai Zasshi |
pmid:1283052
|
Olejniczak ET et al. |
A 4D HCCH-TOCSY experiment for assigning the side chain 1H and 13C resonances of proteins. |
1992 |
J. Biomol. NMR |
pmid:1283353
|
Bauer S et al. |
The effect of the new immunosuppressive drug FK506 on the formation of secondary metabolites of cyclosporin A. |
1992 |
Int J Clin Pharmacol Ther Toxicol |
pmid:1283385
|
Kobayashi N et al. |
Abdominal organ cluster transplantation in pigs receiving FK 506. |
1992 |
Transplant. Proc. |
pmid:1379754
|
Yoshimura R et al. |
A comparative study of cyclosporine vs FK 506: role of kidney microsomal cytochrome P-450. |
1992 |
Transplant. Proc. |
pmid:1379755
|
Yamada K et al. |
FK 506-induced juxtaglomerular apparatus hyperplasia and tubular damage in rat kidney--morphologic and biologic analysis. |
1992 |
Transplant. Proc. |
pmid:1379756
|
Fukuse T et al. |
Optimal dose of FK 506 in canine lung allotransplantation. |
1992 |
Transplant. Proc. |
pmid:1379757
|
Wada H et al. |
Combination use of suboptimal doses of FK 506 and cyclosporine in canine lung transplantation. |
1992 |
Transplant. Proc. |
pmid:1379758
|
Cai X et al. |
Low-dose of FK 506 and associated blood levels in allotransplantation of rat liver, heart, and skin. |
1992 |
Transplant. Proc. |
pmid:1379759
|
Taki J et al. |
DNA analysis of peripheral blood mononuclear cells for early detection of hepatic graft rejection. |
1992 |
Transplant. Proc. |
pmid:1379760
|
Sato Y et al. |
FK 506 suppresses class II antigen expression in regenerating livers following partial hepatectomy in the rat. |
1992 |
Transplant. Proc. |
pmid:1379761
|
Stütz A |
Immunosuppressive macrolides. |
1992 |
Transplant. Proc. |
pmid:1379762
|
Norris AA et al. |
Protective effects of cyclophosphamide, cyclosporin A and FK506 against antigen-induced lung eosinophilia in guinea-pigs. |
1992 |
Clin. Exp. Immunol. |
pmid:1381297
|
Karpas A et al. |
Inhibition of human immunodeficiency virus and growth of infected T cells by the immunosuppressive drugs cyclosporin A and FK 506. |
1992 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:1381509
|
Yatscoff RW and Shaw LM |
Therapeutic monitoring of cyclosporine, FK-506, and rapamycin. |
1992 |
Ther Drug Monit |
pmid:1381530
|
Arceci RJ et al. |
Immunosuppressants FK506 and rapamycin function as reversal agents of the multidrug resistance phenotype. |
1992 |
Blood |
pmid:1381629
|
Pahl A and Keller U |
FK-506-binding proteins from streptomycetes producing immunosuppressive macrolactones of the FK-506 type. |
1992 |
J. Bacteriol. |
pmid:1381710
|
Takahashi N |
[Cyclophilin and FK506-binding protein]. |
1992 |
Seikagaku |
pmid:1381737
|
Lee TK et al. |
Mucosal glutamine utilization after small-bowel transplantation: an electrophysiologic study. |
1992 |
J. Surg. Res. |
pmid:1382152
|
Kaye RE et al. |
Effects of cyclosporin A and FK506 on Fc epsilon receptor type I-initiated increases in cytokine mRNA in mouse bone marrow-derived progenitor mast cells: resistance to FK506 is associated with a deficiency in FK506-binding protein FKBP12. |
1992 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:1382293
|
Edalji R et al. |
High-level expression of recombinant human FK-binding protein from a fusion precursor. |
1992 |
J. Protein Chem. |
pmid:1382438
|
Petros AM et al. |
Identification of solvent-exposed regions of an FK-506 analog, ascomycin, bound to FKBP using a paramagnetic probe. |
1992 |
J. Biomol. NMR |
pmid:1384850
|
Liu J et al. |
The effects of FK-506 and cyclosporin A on the proliferation of PHA-stimulated T cells in response to IL-2, IL-4 or IL-6. |
1992 |
Int. Arch. Allergy Immunol. |
pmid:1384862
|
Mochizuki M et al. |
Preclinical and clinical study of FK506 in uveitis. |
1992 |
Curr. Eye Res. |
pmid:1385045
|
Chung J et al. |
Rapamycin-FKBP specifically blocks growth-dependent activation of and signaling by the 70 kd S6 protein kinases. |
1992 |
Cell |
pmid:1377606
|
Xu RX et al. |
Stereospecific assignments and chi 1 rotamers for FKBP when bound to ascomycin from 3JH alpha,H beta and 3HN,H beta coupling constants. |
1992 |
FEBS Lett. |
pmid:1377648
|
Petros AM et al. |
NMR studies of an FK-506 analog, [U-13C]ascomycin, bound to FK-506-binding protein. |
1992 |
J. Med. Chem. |
pmid:1377749
|
Mizuno K et al. |
Modulation of multidrug resistance by immunosuppressive agents: cyclosporin analogues, FK506 and mizoribine. |
1992 Jan-Feb |
Anticancer Res. |
pmid:1373592
|
Arai S et al. |
The impact of FK506 on graft coronary disease of rat cardiac allograft--a comparison with cyclosporine. |
1992 Jul-Aug |
J. Heart Lung Transplant. |
pmid:1379829
|
Fagiuoli S et al. |
FK 506: a new immunosuppressive agent for organ transplantation. Pharmacology, mechanism of action and clinical applications. |
1992 Jul-Aug |
Ital J Gastroenterol |
pmid:1381245
|
Tong J et al. |
Effect of FK-506 and cyclosporin A on in vitro CFU-GM growth in severe aplastic anemia patients. |
1992 Jul-Aug |
Haematologica |
pmid:1385279
|
Nazer H et al. |
FK 506 associated disorders in liver transplantation. |
1992 May-Jun |
J. Gastroenterol. Hepatol. |
pmid:1377038
|
Bowman H and Lennard TW |
Immunosuppressive drugs. |
1992 Nov 4-17 |
Br J Hosp Med |
pmid:1282440
|
Sattler M et al. |
Cytochrome P-450 3A enzymes are responsible for biotransformation of FK506 and rapamycin in man and rat. |
1992 Sep-Oct |
Drug Metab. Dispos. |
pmid:1385058
|
Kahan BD |
Cyclosporine: the base for immunosuppressive therapy--present and future. |
1993 |
Transplant. Proc. |
pmid:7679819
|
Starzl TE |
FK 506 versus cyclosporine. |
1993 |
Transplant. Proc. |
pmid:7679820
|
Nakajima K et al. |
Effects of triple therapy of cyclosporine, FK 506, and RS-61443 on allogeneic small bowel transplantation in dogs. |
1993 |
Transplant. Proc. |
pmid:7679821
|
Tzakis AG et al. |
Two-year experience with FK 506 in pediatric patients. |
1993 |
Transplant. Proc. |
pmid:7679822
|
Abu-Elmagd KM et al. |
Monitoring and treatment of intestinal allograft rejection in humans. |
1993 |
Transplant. Proc. |
pmid:7680150
|
McCauley J et al. |
FK 506 in the management of nephrotic syndrome after renal transplantation. |
1993 |
Transplant. Proc. |
pmid:7680154
|
Mañez R et al. |
Association between donor-recipient HLA-DR compatibility and cytomegalovirus hepatitis and chronic rejection in liver transplantation. |
1993 |
Transplant. Proc. |
pmid:7680170
|
McCauley J |
The nephrotoxicity of FK506 as compared with cyclosporine. |
1993 |
Curr. Opin. Nephrol. Hypertens. |
pmid:7532089
|
Woan MC et al. |
Characterization of the biopsy growth assay in monitoring cardiac transplant patients for rejection. |
1993 |
Transplant. Proc. |
pmid:7680171
|
Tsai M et al. |
Activation of MAP kinases, pp90rsk and pp70-S6 kinases in mouse mast cells by signaling through the c-kit receptor tyrosine kinase or Fc epsilon RI: rapamycin inhibits activation of pp70-S6 kinase and proliferation in mouse mast cells. |
1993 |
Eur. J. Immunol. |
pmid:7504992
|
Hendrickson BA et al. |
Structural organization of the genes encoding human and murine FK506-binding protein (FKBP) 13 and comparison to FKBP1. |
1993 |
Gene |
pmid:7505249
|
Deardon DJ et al. |
Small bowel tonometry: a possible technique for detecting early small bowel allograft dysfunction. |
1993 |
Transplant. Proc. |
pmid:7505502
|
Frank B et al. |
Neurotoxicity of FK 506 in liver transplant recipients. |
1993 |
Transplant. Proc. |
pmid:7682355
|
Klintmalm GB et al. |
Rejection: FK 506 for rescue or maintenance. |
1993 |
Transplant. Proc. |
pmid:7682356
|
Woodle ES et al. |
Recurrent rejection following FK 506 rescue therapy for acute hepatic allograft rejection. |
1993 |
Transplant. Proc. |
pmid:7682358
|
Woodle ES et al. |
FK 506 rescue therapy: early conversion improves efficacy. |
1993 |
Transplant. Proc. |
pmid:7682359
|
Tokunaga Y et al. |
Living related liver transplantation across ABO blood groups with FK506 and OKT3. |
1993 |
Transpl. Int. |
pmid:7507676
|
Winkler M et al. |
Conversion from cyclosporin to FK 506 after liver transplantation. |
1993 |
Transpl. Int. |
pmid:7507677
|
Nakamura T et al. |
Protein phosphatase type 2B (calcineurin)-mediated, FK506-sensitive regulation of intracellular ions in yeast is an important determinant for adaptation to high salt stress conditions. |
1993 |
EMBO J. |
pmid:7693452
|
Higa A et al. |
Attenuation of epithelial injury in acute experimental colitis by immunomodulators. |
1993 |
Eur. J. Pharmacol. |
pmid:7693488
|
Schmitt J et al. |
Cloning and expression of a mouse cDNA encoding p59, an immunophilin that associates with the glucocorticoid receptor. |
1993 |
Gene |
pmid:7693550
|
Shafiee A et al. |
Enzymatic synthesis and immunosuppressive activity of novel desmethylated immunomycins (ascomycins). |
1993 |
J. Antibiot. |
pmid:7693638
|
Takeda Y et al. |
Stimulation of endothelin mRNA and secretion in human endothelial cells by FK 506. |
1993 |
J. Cardiovasc. Pharmacol. |
pmid:7509973
|
Francavilla A et al. |
Hepatic regeneration and growth factors. |
1993 |
J Surg Oncol Suppl |
pmid:7684910
|
Connelly PR et al. |
Probing hydration contributions to the thermodynamics of ligand binding by proteins. Enthalpy and heat capacity changes of tacrolimus and rapamycin binding to FK506 binding protein in D2O and H2O. |
1993 |
Biochemistry |
pmid:7684925
|
Wallemacq PE et al. |
Improvement and assessment of enzyme-linked immunosorbent assay to detect low FK506 concentrations in plasma or whole blood within 6 hours. |
1993 |
Clin. Chem. |
pmid:7684956
|
Mochizuki M et al. |
A clinical trial of FK506 in refractory uveitis. |
1993 |
Am. J. Ophthalmol. |
pmid:7685147
|
Koga T et al. |
Pulmonary infiltrates recovered by FK506 in a patient with Behçet's disease. |
1993 |
Chest |
pmid:7686837
|
Nishi M et al. |
Effects of the immunosuppressant FK506 on a penetrating keratoplasty rejection model in the rat. |
1993 |
Invest. Ophthalmol. Vis. Sci. |
pmid:7686893
|
Nishizawa S et al. |
Therapeutic effect of a new immunosuppressant, FK-506, on vasospasm after subarachnoid hemorrhage. |
1993 |
Neurosurgery |
pmid:7687044
|
Warty V et al. |
FK506 measurement: comparison of different analytical methods. |
1993 |
Ther Drug Monit |
pmid:7687389
|
Groth CG et al. |
New immunosuppressive drugs in transplantation. |
1993 |
Transplant. Proc. |
pmid:7689274
|
McMaster P and Buist L |
FK 506 in transplantation. |
1993 |
Transplant. Proc. |
pmid:7689275
|
Jost U et al. |
FK 506 treatment of intractable rejection after liver transplantation. |
1993 |
Transplant. Proc. |
pmid:7689276
|
Winkler M et al. |
Plasma level-guided low-dose FK 506 therapy in patients with early liver dysfunction after liver transplantation. |
1993 |
Transplant. Proc. |
pmid:7689277
|
Hacker J and Fischer G |
Immunophilins: structure-function relationship and possible role in microbial pathogenicity. |
1993 |
Mol. Microbiol. |
pmid:7526121
|
Takahashi H and Iizuka H |
Neither cyclosporin A nor FK506 affects adenylate cyclase responses of fetal rat keratinizing epidermal cells (FRSK cells) at concentrations that inhibit thymidine incorporation. |
1993 |
J. Dermatol. Sci. |
pmid:7511000
|