Chen TS et al. |
Microbial transformation of immunosuppressive compounds. I. Desmethylation of FK506 and immunomycin (FR 900520) by Actinoplanes sp. ATCC 53771. |
1992 |
J. Antibiot. |
pmid:1372307
|
Morisaki M and Arai T |
Identity of immunosuppressant FR-900520 with ascomycin. |
1992 |
J. Antibiot. |
pmid:1372308
|
Doi R et al. |
Effects of FK506 on exocrine pancreas in rats. |
1992 |
Pancreas |
pmid:1372739
|
Furukawa H et al. |
The effect of bile duct ligation and bile diversion on FK506 pharmacokinetics in dogs. |
1992 |
Transplantation |
pmid:1373531
|
Chen TS et al. |
Microbial transformation of immunosuppressive compounds. II. Specific desmethylation of 13-methoxy group of FK 506 and FR 900520 by an unidentified Actinomycete ATCC 53828 [corrected]. |
1992 |
J. Antibiot. |
pmid:1375593
|
Meingassner JG and Stütz A |
Immunosuppressive macrolides of the type FK 506: a novel class of topical agents for treatment of skin diseases? |
1992 |
J. Invest. Dermatol. |
pmid:1375617
|
Schneck FX et al. |
Pediatric renal transplantation under FK-506 immunosuppression. |
1992 |
J. Urol. |
pmid:1375663
|
O'Keefe SJ et al. |
FK-506- and CsA-sensitive activation of the interleukin-2 promoter by calcineurin. |
1992 |
Nature |
pmid:1377361
|
Clipstone NA and Crabtree GR |
Identification of calcineurin as a key signalling enzyme in T-lymphocyte activation. |
1992 |
Nature |
pmid:1377362
|
Hasegawa S et al. |
Combination use of suboptimal dose of FK 506 and cyclosporine in canine lung transplantation. |
1992 |
J. Thorac. Cardiovasc. Surg. |
pmid:1279319
|
Min DI et al. |
Visual compatibility of tacrolimus with commonly used drugs during simulated Y-site injection. |
1992 |
Am J Hosp Pharm |
pmid:1282779
|
Mochizuki M |
[Immunotherapy in ocular diseases]. |
1992 |
Nippon Ganka Gakkai Zasshi |
pmid:1283052
|
Fukuse T et al. |
Optimal dose of FK 506 in canine lung allotransplantation. |
1992 |
Transplant. Proc. |
pmid:1379757
|
Wada H et al. |
Combination use of suboptimal doses of FK 506 and cyclosporine in canine lung transplantation. |
1992 |
Transplant. Proc. |
pmid:1379758
|
Cai X et al. |
Low-dose of FK 506 and associated blood levels in allotransplantation of rat liver, heart, and skin. |
1992 |
Transplant. Proc. |
pmid:1379759
|
Taki J et al. |
DNA analysis of peripheral blood mononuclear cells for early detection of hepatic graft rejection. |
1992 |
Transplant. Proc. |
pmid:1379760
|
Arceci RJ et al. |
Immunosuppressants FK506 and rapamycin function as reversal agents of the multidrug resistance phenotype. |
1992 |
Blood |
pmid:1381629
|
Pahl A and Keller U |
FK-506-binding proteins from streptomycetes producing immunosuppressive macrolactones of the FK-506 type. |
1992 |
J. Bacteriol. |
pmid:1381710
|
Takahashi N |
[Cyclophilin and FK506-binding protein]. |
1992 |
Seikagaku |
pmid:1381737
|
Lee TK et al. |
Mucosal glutamine utilization after small-bowel transplantation: an electrophysiologic study. |
1992 |
J. Surg. Res. |
pmid:1382152
|
Chung J et al. |
Rapamycin-FKBP specifically blocks growth-dependent activation of and signaling by the 70 kd S6 protein kinases. |
1992 |
Cell |
pmid:1377606
|
Xu RX et al. |
Stereospecific assignments and chi 1 rotamers for FKBP when bound to ascomycin from 3JH alpha,H beta and 3HN,H beta coupling constants. |
1992 |
FEBS Lett. |
pmid:1377648
|
Petros AM et al. |
NMR studies of an FK-506 analog, [U-13C]ascomycin, bound to FK-506-binding protein. |
1992 |
J. Med. Chem. |
pmid:1377749
|
Jordan ML et al. |
Initial studies with FK506 in renal transplantation. |
1991 Sep-Oct |
Cleve Clin J Med |
pmid:1718631
|
|
FK-506 shows similar graft survival rate to cyclosporine but fewer side effects: Pitt transplant team. |
1991 |
Nephrol News Issues |
pmid:1720511
|
Ito T et al. |
The mechanism of tolerance induced by a perioperative injection of bone marrow cells and a brief course of FK 506. |
1991 |
Transplant. Proc. |
pmid:1703716
|
|
The discovery of FK-506 and U.S. development. |
1991 |
Nephrol News Issues |
pmid:1720512
|
Zheng B et al. |
Effects of the new and highly active immunosuppressant, rapamycin, on lymphoid tissues and cells in vivo. |
1991 |
Transplant. Proc. |
pmid:1703717
|
Mieles L et al. |
Interaction between FK506 and clotrimazole in a liver transplant recipient. |
1991 |
Transplantation |
pmid:1721250
|
Yabuuchi H et al. |
Prominent prolongation of islet xenograft survival in combination therapy with FK 506 and 15-deoxyspergualin. |
1991 |
Transplant. Proc. |
pmid:1703718
|
|
First International Congress on FK 506. August 21-24, 1991, Pittsburgh, PA. |
1991 |
Transplant. Proc. |
pmid:1721253
|
Goto T et al. |
FK 506: historical perspectives. |
1991 |
Transplant. Proc. |
pmid:1721254
|
Ochiai T et al. |
Effective and safe use of FK 506: combination treatment with rapamycin or RS-61443 in experimental organ transplantation. |
1991 |
Transplant. Proc. |
pmid:1721255
|
Habucky K et al. |
The pharmacodynamics of pentobarbital following FK 506 therapy. |
1991 |
Transplant. Proc. |
pmid:1721282
|
Farghali H et al. |
Effect of FK 506 chronic administration on bromosulphthalein hepatic excretion in rats. |
1991 |
Transplant. Proc. |
pmid:1721283
|
Farghali H et al. |
A biochemical and 31P-NMR investigation of the effect of FK 506 and cyclosporine pretreatment on immobilized hepatocytes perifused with ethanol. |
1991 |
Transplant. Proc. |
pmid:1721284
|
Farghali H et al. |
FK 506 modulates D-galactosamine-induced hepatitis in rats. |
1991 |
Transplant. Proc. |
pmid:1721285
|
Müller MK et al. |
Inhibition of insulin release by FK 506 and its prevention by rioprostil, a stable prostaglandin E1 analogue. |
1991 |
Transplant. Proc. |
pmid:1721286
|
Francavilla A et al. |
The effects of FK 506, cyclosporine, and rapamycin on liver growth in vitro and in vivo. |
1991 |
Transplant. Proc. |
pmid:1721287
|
McCarthy SA et al. |
Effects of FK 506 and cyclosporine on T-cell tolerance: inhibition of a "protective" mechanism that regulates activation-induced apoptosis in developing thymocytes. |
1991 |
Transplant. Proc. |
pmid:1721314
|
Zeevi A et al. |
Comparative in vitro studies on the immunosuppressive activities of mycophenolic acid, bredinin, FK 506, cyclosporine, and rapamycin. |
1991 |
Transplant. Proc. |
pmid:1721315
|
Matsuura T et al. |
Beneficial immunosuppressive effect of combined use of FK 506 and cyclosporine assessed by proliferative responses of cloned human T cells. |
1991 |
Transplant. Proc. |
pmid:1721316
|
Jiang H et al. |
Combined immunosuppressive effect of FK 506 and other immunosuppressive agents on PHA- and CD3-stimulated human lymphocyte proliferation in vitro. |
1991 |
Transplant. Proc. |
pmid:1721317
|
Yagihashi A et al. |
The effect of FK 506 on peripheral blood T-lymphocyte subsets in orthotopic liver transplant patients. |
1991 |
Transplant. Proc. |
pmid:1721318
|
Woo J et al. |
Effects of FK 506, mycophenolic acid, and bredinin on OKT-3-, PMA-, and alloantigen-induced activation molecule expression on cultured CD4+ and CD8+ human lymphocytes. |
1991 |
Transplant. Proc. |
pmid:1721319
|
Nakamura K et al. |
The lymphocytotoxic crossmatch in liver transplantation: a clinicopathologic analysis. |
1991 |
Transplant. Proc. |
pmid:1721346
|
Jain AB et al. |
Correlation of rejection episodes with FK 506 dosage, FK 506 level, and steroids following primary orthotopic liver transplant. |
1991 |
Transplant. Proc. |
pmid:1721347
|
Takaya S et al. |
Retransplantation of liver: a comparison of FK 506- and cyclosporine-treated patients. |
1991 |
Transplant. Proc. |
pmid:1721348
|
Morel P et al. |
Liver retransplantation in adults: overall results and determinant factors affecting the outcome. |
1991 |
Transplant. Proc. |
pmid:1721349
|
Felser I et al. |
Changes in quality of life following conversion from CyA to FK 506 in orthotopic liver transplant patients. |
1991 |
Transplant. Proc. |
pmid:1721350
|
Schreiber SL |
Chemistry and biology of the immunophilins and their immunosuppressive ligands. |
1991 |
Science |
pmid:1702904
|
Alessiani M et al. |
CMV infection in liver transplantation under cyclosporine or FK 506 immunosuppression. |
1991 |
Transplant. Proc. |
pmid:1721351
|
Wasik M et al. |
Effect of FK506 versus cyclosporine on human natural and antibody-dependent cytotoxicity reactions in vitro. |
1991 |
Transplantation |
pmid:1702910
|
Perico N et al. |
FK 506 does not affect the glomerular filtration rate and renal plasma flow in the rat. |
1991 |
Transplant. Proc. |
pmid:1721378
|
Mieles L et al. |
Glycemia and insulin need following FK 506 rescue therapy in liver transplant recipients. |
1991 |
Transplant. Proc. |
pmid:1703362
|
Wagner K et al. |
Effect of FK 506 on excretion of urinary enzymes in rats. |
1991 |
Transplant. Proc. |
pmid:1721379
|
Warty V et al. |
Distribution of FK 506 in plasma lipoproteins in transplant patients. |
1991 |
Transplant. Proc. |
pmid:1703363
|
Prasad SJ et al. |
In vitro effects of cyclosporine and FK 506 on the renal cortex. |
1991 |
Transplant. Proc. |
pmid:1721380
|
Kusne S et al. |
Early infections in kidney transplant recipients under FK 506. |
1991 |
Transplant. Proc. |
pmid:1703364
|
Yamada K et al. |
Short-term FK 506-induced morphological changes in rat kidneys. |
1991 |
Transplant. Proc. |
pmid:1721381
|
Moutabarrik A et al. |
FK 506 mechanism of nephrotoxicity: stimulatory effect on endothelin secretion by cultured kidney cells and tubular cell toxicity in vitro. |
1991 |
Transplant. Proc. |
pmid:1721382
|
Moutabarrik A et al. |
In vitro FK 506 kidney tubular cell toxicity. |
1991 |
Transplant. Proc. |
pmid:1721383
|
Tai J et al. |
In vivo and in vitro effect of FK 506 on rat Leydig cell function. |
1991 |
Transplant. Proc. |
pmid:1721409
|
Ricordi C et al. |
Human islet allotransplantation under FK 506. |
1991 |
Transplant. Proc. |
pmid:1721410
|
Tze WJ et al. |
Long-term survival of islet allografts in diabetic rats treated with FK 506. |
1991 |
Transplant. Proc. |
pmid:1721411
|
Wang X et al. |
Intraportal FK 506 improves intrahepatic islet allograft survival. |
1991 |
Transplant. Proc. |
pmid:1721412
|
Ohtsuka S et al. |
The effect of short-term FK 506 therapy on pancreas transplantation in rats. |
1991 |
Transplant. Proc. |
pmid:1721413
|
Yamashita T et al. |
Prolongation of pancreaticoduodenal allograft survival in rats by treatment with FK 506. |
1991 |
Transplant. Proc. |
pmid:1721414
|
Markus PM et al. |
Effects of in vivo treatment with FK506 on natural killer cells in rats. |
1991 |
Transplantation |
pmid:1707562
|
Lin CS et al. |
FK-506 and cyclosporin A inhibit highly similar signal transduction pathways in human T lymphocytes. |
1991 |
Cell. Immunol. |
pmid:1707760
|
Vincent SH et al. |
Effects of the immunosuppressant FK-506 and its analog FK-520 on hepatic and renal cytochrome P450 mixed-function oxidase. |
1991 |
Biochem. Pharmacol. |
pmid:1708254
|
Kitahara S et al. |
Lymphoproliferative disorders after FK 506. |
1991 |
Lancet |
pmid:1708846
|
Holechek MJ |
Medication review: FK 506. |
1991 |
ANNA J |
pmid:1708982
|
Michnick SW et al. |
Solution structure of FKBP, a rotamase enzyme and receptor for FK506 and rapamycin. |
1991 |
Science |
pmid:1709301
|
Katayama Y et al. |
Immunosuppressive effects of FK 506 in rat lung transplantation. |
1991 |
Transplant. Proc. |
pmid:1721441
|
Yokomise H et al. |
Immunosuppressive effects of FK 506 in canine lung transplantation. |
1991 |
Transplant. Proc. |
pmid:1721442
|
Hasegawa S et al. |
FK 506 and cyclosporine: effects and side effects in canine lung transplantation. |
1991 |
Transplant. Proc. |
pmid:1721443
|
Wada H et al. |
Dose response to FK 506 in canine lung transplantation. |
1991 |
Transplant. Proc. |
pmid:1721444
|
Lin CY et al. |
Effects of FK 506 on the biochemical markers in canine lung allograft rejection. |
1991 |
Transplant. Proc. |
pmid:1721445
|
Propper DJ et al. |
Evidence that FK 506 may abrogate suppressor cell activity induced by blood transfusion. |
1991 |
Transplant. Proc. |
pmid:1721446
|
Vathsala A et al. |
The immunosuppressive antagonism of low doses of FK506 and cyclosporine. |
1991 |
Transplantation |
pmid:1713361
|
Kawano K et al. |
A protective effect of FK506 in ischemically injured rat livers. |
1991 |
Transplantation |
pmid:1713362
|
Armitage JM et al. |
Preliminary experience with FK506 in thoracic transplantation. |
1991 |
Transplantation |
pmid:1713363
|
Lorber MI et al. |
A comparison of in vivo responses to cyclosporine, FK506, and rapamycin following allogeneic immune challenge. |
1991 |
Transplantation |
pmid:1713364
|
Abu-Elmagd K et al. |
The effect of graft function on FK506 plasma levels, dosages, and renal function, with particular reference to the liver. |
1991 |
Transplantation |
pmid:1713365
|
Takada K et al. |
Pharmacokinetics of FK-506, a novel immunosuppressant, after intravenous and oral administrations to rats. |
1991 |
J. Pharmacobio-dyn. |
pmid:1713626
|
Chen MF et al. |
The influence of FK-506 on the thymus and spleen in normal C3H/He mice: flow cytometric analysis of lymphocyte subpopulations. |
1991 |
Immunol. Lett. |
pmid:1722778
|
Sakai K et al. |
The effect of a new immunosuppressive agent, FK-506, on xenogeneic neural transplantation in rodents. |
1991 |
Brain Res. |
pmid:1723023
|
Forrest MJ et al. |
FK-506 and cyclosporin A: selective inhibition of calcium ionophore-induced polymorphonuclear leukocyte degranulation. |
1991 |
Biochem. Pharmacol. |
pmid:1716098
|
Weaver JL et al. |
Comparison of the in vitro and biophysical effects of cyclosporine A, FK-506, and mycophenolic acid on human peripheral blood lymphocytes. |
1991 |
Immunopharmacol Immunotoxicol |
pmid:1723084
|
DiLella AG and Craig RJ |
Exon organization of the human FKBP-12 gene: correlation with structural and functional protein domains. |
1991 |
Biochemistry |
pmid:1716149
|
Burres NS et al. |
Dunaimycins, a new complex of spiroketal 24-membered macrolides with immunosuppressive activity. III. Immunosuppressive activities of dunaimycins. |
1991 |
J. Antibiot. |
pmid:1723403
|
Nielsen JB et al. |
Biosynthesis of the immunosuppressant immunomycin: the enzymology of pipecolate incorporation. |
1991 |
Biochemistry |
pmid:2043618
|
McKeon F |
When worlds collide: immunosuppressants meet protein phosphatases. |
1991 |
Cell |
pmid:1716181
|
Petros AM et al. |
NMR studies of an FK-506 analogue, [U-13C]ascomycin, bound to FKBP: conformation and regions of ascomycin involved in binding. |
1991 |
J. Med. Chem. |
pmid:1716684
|
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FK 506--an investigational immunosuppressant. |
1991 |
Med Lett Drugs Ther |
pmid:1716722
|
Jamieson NV et al. |
Orthotopic liver transplantation at Addenbrooke's Hospital Cambridge 1968 to 1991. |
1991 |
Clin Transpl |
pmid:1726459
|
Takahara S et al. |
Survival of cardiac allograft in highly sensitized and nonsensitized rats treated with FK506. |
1991 |
J Clin Lab Immunol |
pmid:1726566
|
Stötter H and Lotze MT |
Human lymphokine-activated killer cell activity. Role of IL-2, IL-4, and IL-7. |
1991 |
Arch Surg |
pmid:1726819
|
Karlsson H and Nässberger L |
FK506 lacks the ability to inhibit expression of interleukin-2 receptor beta-chain on human lymphocytes. |
1991 |
J Clin Lab Immunol |
pmid:1726895
|