tacrolimus

Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.

Cross Reference

Introduction

To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with tacrolimus?

tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with tacrolimus

MeSH term MeSH ID Detail
Abnormalities, Multiple D000015 13 associated lipids
Abortion, Spontaneous D000022 12 associated lipids
Acne Vulgaris D000152 35 associated lipids
Adenocarcinoma D000230 166 associated lipids
Adrenal Insufficiency D000309 3 associated lipids
Akinetic Mutism D000405 1 associated lipids
Albuminuria D000419 18 associated lipids
Alopecia D000505 14 associated lipids
Alopecia Areata D000506 6 associated lipids
Alzheimer Disease D000544 76 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with tacrolimus

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with tacrolimus?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with tacrolimus?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with tacrolimus?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with tacrolimus?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with tacrolimus?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with tacrolimus

Download all related citations
Per page 10 20 50 100 | Total 15051
Authors Title Published Journal PubMed Link
Sugimoto K et al. Assessment of Long-Term Efficacy and Safety of Adalimumab in Patients with Ulcerative Colitis: Results from a 6-Year Real-World Clinical Practice. 2019 Dig Dis pmid:30205400
Kanda J et al. Effects of the calcineurin inhibitors cyclosporine and tacrolimus on bone metabolism in rats. 2018 Biomed. Res. pmid:29899188
Komura Y et al. Economic assessment of actual prescription of drugs for treatment of atopic dermatitis: Differences between dermatology and pediatrics in large-scale receipt data. 2018 J. Dermatol. pmid:29168213
Cho EJ et al. Performance of the Dimension TAC assay and comparison of multiple platforms for the measurement of tacrolimus. 2018 J. Clin. Lab. Anal. pmid:29148096
Sir G et al. Antagonistic Effect of Oxytocin and Tacrolimus Combination on Adipose Tissue - Derived Mesenchymal Stem Cells: Antagonistic effect of oxytocin and tacrolimus. 2018 Biomed. Pharmacother. pmid:29136956
Wu MF et al. Combination Therapy of Tacrolimus and Chinese Herb Medicated Bath in Children with Inverse Psoriasis. 2018 Chin J Integr Med pmid:28914435
Akamine Y et al. A comparison of the effects of CYP3A5 polymorphism on tacrolimus blood concentrations measured by 4 immunoassay methods in renal transplant patients. 2018 J Clin Pharm Ther pmid:28891077
Mithani Z et al. De Novo Donor-Specific Antibody Formation in Tacrolimus-Based, Mycophenolate Versus Mammalian Target of Rapamycin Immunosuppressive Regimens. 2018 Exp Clin Transplant pmid:28332959
Velioglu A et al. Late Pulmonary Toxicity Associated With Everolimus in a Renal Transplant Patient and Review of the Literature. 2018 Exp Clin Transplant pmid:27001620
Choong CL et al. Dose-Response Relationship Between Diltiazem and Tacrolimus and Its Safety in Renal Transplant Recipients. 2018 Transplant. Proc. pmid:30316389
Cheng CY et al. Intervention of Online Percent Coefficient of Variation Reporting System Reduces the Variability of Tacrolimus Trough Concentration in Kidney Transplant Recipients. 2018 Transplant. Proc. pmid:30316366
Liu Y et al. Delayed Initiation of Tacrolimus Is Safe and Effective in Renal Transplant Recipients With Delayed and Slow Graft Function. 2018 Transplant. Proc. pmid:30316359
Nordheim E et al. Preserved insulin secretion and kidney function in recipients with functional pancreas grafts 1 year after transplantation: a single-center prospective observational study 2018 Eur. J. Endocrinol. pmid:30299895
Pflugrad H et al. Longterm calcineurin inhibitor therapy and brain function in patients after liver transplantation. 2018 Liver Transpl. pmid:29156491
Loeschenberger B et al. Calcineurin inhibitor-induced complement system activation via ERK1/2 signalling is inhibited by SOCS-3 in human renal tubule cells. 2018 Eur. J. Immunol. pmid:29143318
Sugahara S et al. Integrin, alpha9 subunit blockade suppresses collagen-induced arthritis with minimal systemic immunomodulation. 2018 Eur. J. Pharmacol. pmid:29932925
Wen L et al. Transient High Pressure in Pancreatic Ducts Promotes Inflammation and Alters Tight Junctions via Calcineurin Signaling in Mice. 2018 Gastroenterology pmid:29928898
Ohtsuki M et al. Tacrolimus ointment for the treatment of adult and pediatric atopic dermatitis: Review on safety and benefits. 2018 J. Dermatol. pmid:29927498
Shimoda-Komatsu Y et al. Chronological observation of surgically-treated granuloma faciale implies the necessity of circumspect management for perinasal nodular subset. 2018 J. Dermatol. pmid:29905388
Hou Y et al. Management of hepatic vein occlusive disease after liver transplantation: A case report with literature review. 2018 Medicine (Baltimore) pmid:29901618
Özçakar ZB et al. Transplantation within the era of anti-IL-1 therapy: case series of five patients with familial Mediterranean fever-related amyloidosis. 2018 Transpl. Int. pmid:29957882
Chao YH et al. Tolerogenic β2-glycoprotein I DNA vaccine and FK506 as an adjuvant attenuates experimental obstetric antiphospholipid syndrome. 2018 PLoS ONE pmid:29894515
Luaces-Rodríguez A et al. Preclinical characterization and clinical evaluation of tacrolimus eye drops. 2018 Eur J Pharm Sci pmid:29705214
Castedal M et al. Steroid-free immunosuppression with low-dose tacrolimus is safe and significantly reduces the incidence of new-onset diabetes mellitus following liver transplantation. 2018 Scand. J. Gastroenterol. pmid:29688072
Zhang Y and Zhang R Recent advances in analytical methods for the therapeutic drug monitoring of immunosuppressive drugs. 2018 Drug Test Anal pmid:28851030
Niel O and Bastard P Artificial intelligence improves estimation of tacrolimus area under the concentration over time curve in renal transplant recipients. 2018 Transpl. Int. pmid:29687486
Gmitterová K et al. Tacrolimus-induced parkinsonism in a patient after liver transplantation - case report. 2018 BMC Neurol pmid:29678162
Liu HY et al. Ribavirin-induced anaemia reduced tacrolimus level in a hepatitis C patient receiving haemodialysis. 2018 BMJ Case Rep pmid:29669765
Majeed A et al. A 20-year experience with nocardiosis in solid organ transplant (SOT) recipients in the Southwestern United States: A single-center study. 2018 Transpl Infect Dis pmid:29668074
Mah A et al. Graft loss attributed to possible transfusion-transmitted ehrlichiosis following cord blood stem cell transplant. 2018 Transpl Infect Dis pmid:29668040
Hu T et al. Tacrolimus decreases proteinuria in patients with refractory IgA nephropathy. 2018 Medicine (Baltimore) pmid:29718866
Ekici Günay N et al. Administration of Extract (EGb761) Alone and in Combination with FK506 Promotes Liver Regeneration in a Rat Model of Partial Hepatectomy. 2018 Balkan Med J pmid:29553465
Zhang X et al. Current progress of tacrolimus dosing in solid organ transplant recipients: Pharmacogenetic considerations. 2018 Biomed. Pharmacother. pmid:29550633
Komine N et al. Influence of CYP3A5 genetic differences in tacrolimus on quantitative interstitial fibrosis and long-term graft function in kidney transplant recipients. 2018 Int. Immunopharmacol. pmid:29550576
Kagaya H et al. Prediction of Tacrolimus Exposure by CYP3A5 Genotype and Exposure of Co-Administered Everolimus in Japanese Renal Transplant Recipients. 2018 Int J Mol Sci pmid:29547545
Yamada R et al. A case of duodenal malignant lymphoma presenting as acute pancreatitis: systemic lupus erythematosus and immunosuppressive therapy as risk factors. 2018 Clin J Gastroenterol pmid:29546569
Shi D et al. CYP3A4 and GCK genetic polymorphisms are the risk factors of tacrolimus-induced new-onset diabetes after transplantation in renal transplant recipients. 2018 Eur. J. Clin. Pharmacol. pmid:29546446
Mina M et al. Comparison between the efficacy of microneedling combined with 5-fluorouracil vs microneedling with tacrolimus in the treatment of vitiligo. 2018 J Cosmet Dermatol pmid:29532621
Qin X et al. Multi-center Performance Evaluations of Tacrolimus and Cyclosporine Electrochemiluminescence Immunoassays in the Asia-Pacific Region. 2018 Ann Lab Med pmid:29214751
Wan Q et al. Therapeutic Effect of 0.1% Tacrolimus Eye Drops in the Tarsal Form of Vernal Keratoconjunctivitis. 2018 Ophthalmic Res. pmid:28803239
Fu Q et al. Risk Factors for Acute Rejection After Deceased Donor Kidney Transplantation in China. 2018 Transplant. Proc. pmid:30316380
Konno O et al. Early Outcomes of Living-Donor Kidney Transplantation With Immunosuppression Therapy Induction With Tacrolimus Extended-Release: A Comparison With Cyclosporine. 2018 Transplant. Proc. pmid:30316378
Tsujimura K et al. Effect of Influenza Vaccine in Patients With Kidney Transplant. 2018 Transplant. Proc. pmid:30316375
Yu M et al. Pharmacokinetics, Pharmacodynamics and Pharmacogenetics of Tacrolimus in Kidney Transplantation. 2018 Curr. Drug Metab. pmid:29380698
Kim JH et al. Increased Exposure of Tacrolimus by Co-administered Mycophenolate Mofetil: Population Pharmacokinetic Analysis in Healthy Volunteers. 2018 Sci Rep pmid:29374217
Xia T et al. Targeted metabolomic analysis of 33 amino acids and biogenic amines in human urine by ion-pairing HPLC-MS/MS: Biomarkers for tacrolimus nephrotoxicity after renal transplantation. 2018 Biomed. Chromatogr. pmid:29369388
Song JL et al. Higher tacrolimus blood concentration is related to increased risk of post-transplantation diabetes mellitus after living donor liver transplantation. 2018 Int J Surg pmid:29360611
Charnaya O et al. Results of early treatment for de novo donor-specific antibodies in pediatric kidney transplant recipients in a cross-sectional and longitudinal cohort. 2018 Pediatr Transplant pmid:29356221
Yamada K et al. Correlation between disease activity and serum ferritin in clinically amyopathic dermatomyositis with rapidly-progressive interstitial lung disease: a case report. 2018 BMC Res Notes pmid:29338781
Jin L et al. Effect of Conversion to CTLA4Ig on Tacrolimus-Induced Diabetic Rats. 2018 Transplantation pmid:29319618