| MeSH term | MeSH ID | Detail |
|---|---|---|
| Abnormalities, Multiple | D000015 | 13 associated lipids |
| Abortion, Spontaneous | D000022 | 12 associated lipids |
| Acne Vulgaris | D000152 | 35 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Adrenal Insufficiency | D000309 | 3 associated lipids |
| Akinetic Mutism | D000405 | 1 associated lipids |
| Albuminuria | D000419 | 18 associated lipids |
| Alopecia | D000505 | 14 associated lipids |
| Alopecia Areata | D000506 | 6 associated lipids |
| Alzheimer Disease | D000544 | 76 associated lipids |
tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- Am. J. Physiol. Renal Physiol. (1)
- Drug Metab. Dispos. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| pmid:8615615 | ||||
| Payabvash S et al. | Cerebellar superficial siderosis of chronic subarachnoid hemorrhage in a patient with Tacrolimus-associated posterior reversible encephalopathy. | J Postgrad Med | pmid:25370549 | |
| Akoglu H et al. | Relationship between hemorheology and endothelial dysfunction in renal transplant patients receiving calcineurin inhibitors. | J. Nephrol. | pmid:23147686 | |
| pmid:19200227 | ||||
| Bethke G et al. | Swiss Dent J | pmid:28639684 | ||
| Luger T et al. | Recommendations for pimecrolimus 1% cream in the treatment of mild-to-moderate atopic dermatitis: from medical needs to a new treatment algorithm. | Eur J Dermatol | pmid:24185493 | |
| Park J et al. | Persistent generalized lichen nitidus successfully treated with 0.03% tacrolimus ointment. | Eur J Dermatol | pmid:24184632 | |
| Henrique Pinto C et al. | Targeted preemptive therapy according to perceived risk of CMV infection after kidney transplantation. | Braz J Infect Dis | pmid:27643978 | |
| Fernández C et al. | Kidney transplantation from HLA-incompatible live donors: Efficiency and outcome of 32 patients after desensitisation. | Nefrologia | pmid:28734583 | |
| Kathuria S et al. | Segmental vitiligo: a randomized controlled trial to evaluate efficacy and safety of 0.1% tacrolimus ointment vs 0.05% fluticasone propionate cream. | Indian J Dermatol Venereol Leprol | pmid:22199063 | |
| Hirohata A et al. | Oral tacrolimus for the treatment of generalized morphea. | Eur J Dermatol | pmid:26679400 | |
| López-Oliva MO et al. | Switch to belatacept in kidney graft recipients. | Nefrologia | pmid:28233569 | |
| Takahashi Y et al. | Pharmacokinetic Profile of Twice- and Once-daily Tacrolimus in Pediatric Kidney Transplant Recipients. | Transplant. Proc. | pmid:28104153 | |
| Shi Y et al. | Comparison of Mizoribine and Mycophenolate Mofetil With a Tacrolimus-Based Immunosuppressive Regimen in Living-Donor Kidney Transplantation Recipients: A Retrospective Study in China. | Transplant. Proc. | pmid:28104150 | |
| Pan D et al. | Tacrolimus-associated Diffuse Gastrointestinal Ulcerations and Pathergy: A Case Report. | Transplant. Proc. | pmid:28104141 | |
| Jiménez-Pérez M et al. | Everolimus plus mycophenolate mofetil as initial immunosuppression in liver transplantation. | Transplant. Proc. | pmid:25645779 | |
| Polanco N et al. | Everolimus-based immunosuppression therapy for BK virus nephropathy. | Transplant. Proc. | pmid:25645770 | |
| Nojima M et al. | Immunosuppression Modification by Everolimus With Minimization of Calcineurin Inhibitors Recovers Kidney Graft Function Even in Patients With Very Late Conversion and Also With Poor Graft Function. | Transplant. Proc. | pmid:28104155 | |
| López-Vilella R et al. | Incidence of development of obesity after heart transplantation according to the calcineurin inhibitor. | Transplant. Proc. | pmid:25645789 | |
| Tinoco R et al. | [A case of de novo inflammatory bowel disease after liver transplantation for cryptogenic cirrhosis]. | Gastroenterol Hepatol | pmid:26321322 | |
| pmid:28590598 | ||||
| pmid:28422431 | ||||
| Al-Amri AM et al. | Tacrolimus Ointment for Treatment of Vernal Keratoconjunctivitis. | Middle East Afr J Ophthalmol | pmid:26957853 | |
| Collier DS et al. | FK-506 in experimental renal allografts. | 1987 | Transplant. Proc. | pmid:2445063 |
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| Lim SM et al. | Heterotopic heart transplantation in the rat receiving FK-506. | 1987 | Transplant. Proc. | pmid:2445080 |
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| Kino T et al. | FK-506, a novel immunosuppressant isolated from a Streptomyces. I. Fermentation, isolation, and physico-chemical and biological characteristics. | 1987 | J. Antibiot. | pmid:2445721 |
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| Ochiai T et al. | Studies of the effects of FK506 on renal allografting in the beagle dog. | 1987 | Transplantation | pmid:2447688 |
| Ochiai T et al. | Studies of the induction and maintenance of long-term graft acceptance by treatment with FK506 in heterotopic cardiac allotransplantation in rats. | 1987 | Transplantation | pmid:2447689 |
| Ochiai T et al. | Effect of a new immunosuppressive agent, FK 506, on heterotopic cardiac allotransplantation in the rat. | 1987 | Transplant. Proc. | pmid:2484094 |
| Sawada S et al. | Novel immunosuppressive agent, FK506. In vitro effects on the cloned T cell activation. | 1987 | J. Immunol. | pmid:2442255 |
| Inamura N et al. | Immunosuppressive effect of FK506 on collagen-induced arthritis in rats. | 1988 | Clin. Immunol. Immunopathol. | pmid:2446810 |
| Inamura N et al. | Prolongation of skin allograft survival in rats by a novel immunosuppressive agent, FK506. | 1988 | Transplantation | pmid:2447690 |
| Ochiai T et al. | Studies on FK506 in experimental organ transplantation. | 1988 | Transplant. Proc. | pmid:2450414 |
| Immunosuppression: FK506. | 1988 | Transplant. Proc. | pmid:2450415 | |
| Todo S et al. | Effect of FK506 in experimental organ transplantation. | 1988 | Transplant. Proc. | pmid:2450416 |
| Tsuchimoto S et al. | [Orthotopic liver transplantation in the rat--immunosuppressive effect of FR100906 on the survival of liver allografts]. | 1988 | Nihon Geka Gakkai Zasshi | pmid:2452341 |
| Nakajima K et al. | Prolongation of cardiac xenograft survival in rats treated with 15-deoxyspergualin alone and in combination with FK506. | 1988 | Transplantation | pmid:2454521 |
| Todo S et al. | Immunosuppression of canine, monkey, and baboon allografts by FK 506: with special reference to synergism with other drugs and to tolerance induction. | 1988 | Surgery | pmid:2456627 |
| Kawashima H et al. | Effects of a new immunosuppressive agent, FK506, on experimental autoimmune uveoretinitis in rats. | 1988 | Invest. Ophthalmol. Vis. Sci. | pmid:2458329 |
| Warty V et al. | FK506: a novel immunosuppressive agent. Characteristics of binding and uptake by human lymphocytes. | 1988 | Transplantation | pmid:2458643 |
| Hewitt CW and Black KS | Comparative studies of FK506 with cyclosporine. | 1988 | Transplantation | pmid:2458644 |
| Woo J et al. | Spleen lymphocyte populations and expression of activation markers in rats treated with the potent new immunosuppressive agent FK-506. | 1988 | Immunology | pmid:2460401 |
| Hatanaka H et al. | FR-900520 and FR-900523, novel immunosuppressants isolated from a Streptomyces. II. Fermentation, isolation and physico-chemical and biological characteristics. | 1988 | J. Antibiot. | pmid:2461926 |
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| Hatanaka H et al. | FR-900520 and FR-900523, novel immunosuppressants isolated from a Streptomyces. I. Taxonomy of the producing strain. | 1988 | J. Antibiot. | pmid:3198493 |
| Yoshimura N et al. | Effect of a new immunosuppressive agent, FK506, on human lymphocyte responses in vitro. I. Inhibition of expression of alloantigen-activated suppressor cells, as well as induction of alloreactivity. | 1989 | Transplantation | pmid:2465592 |
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| Takabayashi K et al. | Effect of FK-506, a novel immunosuppressive drug on murine systemic lupus erythematosus. | 1989 | Clin. Immunol. Immunopathol. | pmid:2466594 |
| Morris RE et al. | Immunopharmacology of FK-506. | 1989 | Transplant. Proc. | pmid:2468201 |
| Yoshimura N et al. | A new immunosuppressive agent, FK506, inhibits the expression of alloantigen-activated suppressor cells as well as the induction of alloreactivity. | 1989 | Transplant. Proc. | pmid:2468202 |
| Thomson AW et al. | Immunosuppressive activity, T-cell subset analysis, and acute toxicity of FK-506 in rats. | 1989 | Transplant. Proc. | pmid:2468203 |
| Sanghvi A et al. | Increased cyclosporine uptake by cells pretreated with FK506 and evidence for binding of both drugs to a common intracellular protein. | 1989 | Transplant. Proc. | pmid:2468204 |
| Takagishi K et al. | Effects of FK-506 on collagen arthritis in mice. | 1989 | Transplant. Proc. | pmid:2468205 |
| Arita C et al. | Effect of FK 506 (FR 900506) on collagen arthritis in rats: a preliminary report. | 1989 | Transplant. Proc. | pmid:2468206 |
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| Tsuchimoto S et al. | Orthotopic liver transplantation in rats receiving FK506. | 1989 | Transplant. Proc. | pmid:2468208 |
| Yokota K et al. | Comparative studies of FK506 and cyclosporine in canine orthotopic hepatic allograft survival. | 1989 | Transplant. Proc. | pmid:2468209 |
| Inagaki K et al. | Effects of FK506 and 15-deoxyspergualin in rat orthotopic liver transplantation. | 1989 | Transplant. Proc. | pmid:2468210 |
| Gudas VM et al. | Comparison of the immunosuppressive and toxic effects of FK506 and cyclosporine in xenograft recipients. | 1989 | Transplant. Proc. | pmid:2468211 |
| Sato K et al. | Pancreaticoduodenal allotransplantation with cyclosporine and FK506. | 1989 | Transplant. Proc. | pmid:2468212 |
| Gschwendt M et al. | The immunosuppressant FK-506, like cyclosporins and didemnin B, inhibits calmodulin-dependent phosphorylation of the elongation factor 2 in vitro and biological effects of the phorbol ester TPA on mouse skin in vivo. | 1989 | Immunobiology | pmid:2471685 |
| Fujii Y et al. | Effect of a novel immunosuppressive agent, FK506, on mitogen-induced inositol phospholipid degradation in rat thymocytes. | 1989 | Transplantation | pmid:2472025 |
| Tocci MJ et al. | The immunosuppressant FK506 selectively inhibits expression of early T cell activation genes. | 1989 | J. Immunol. | pmid:2472451 |
| Beck Y and Akiyama N | Effect of FK-506 and cyclosporine on human lymphocyte responses in vitro. | 1989 | Transplant. Proc. | pmid:2472695 |
| Thomson AW | FK-506--how much potential? | 1989 | Immunol. Today | pmid:2473767 |
| Ochiai T et al. | Optimal serum trough levels of FK506 in renal allotransplantation of the beagle dog. | 1989 | Transplantation | pmid:2474208 |
| Ochiai T et al. | Effects of combination treatment with FK506 and cyclosporine on survival time and vascular changes in renal-allograft-recipient dogs. | 1989 | Transplantation | pmid:2474209 |
| Siekierka JJ et al. | FK-506, a potent novel immunosuppressive agent, binds to a cytosolic protein which is distinct from the cyclosporin A-binding protein, cyclophilin. | 1989 | J. Immunol. | pmid:2474605 |
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| Todo S et al. | Renal transplantation in baboons under FK 506. | 1989 | Surgery | pmid:2474865 |
| Kay JE et al. | Inhibition of T-lymphocyte activation by the immunosuppressive drug FK-506. | 1989 | Immunology | pmid:2475433 |
| Moriyama S | [Experimental tracheal reconstruction by allotransplantation]. | 1989 | Nihon Kyobu Geka Gakkai Zasshi | pmid:2475555 |
| Freedman RB | Immunosuppression. Convergence of drug action. | 1989 | Nature | pmid:2477712 |
| Siekierka JJ et al. | A cytosolic binding protein for the immunosuppressant FK506 has peptidyl-prolyl isomerase activity but is distinct from cyclophilin. | 1989 | Nature | pmid:2477714 |
| Harding MW et al. | A receptor for the immunosuppressant FK506 is a cis-trans peptidyl-prolyl isomerase. | 1989 | Nature | pmid:2477715 |
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| Leonard DK et al. | Toxicity of FK-506 in human fetal pancreas. | 1989 | Diabetes | pmid:2463195 |
| Stephen M et al. | Immunosuppressive activity, lymphocyte subset analysis, and acute toxicity of FK-506 in the rat. A comparative and combination study with cyclosporine. | 1989 | Transplantation | pmid:2463701 |