tacrolimus

Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.

Cross Reference

Introduction

To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with tacrolimus?

tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with tacrolimus

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Uremia D014511 33 associated lipids
Colitis, Ulcerative D003093 24 associated lipids
Stomach Ulcer D013276 75 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Nocardia Infections D009617 6 associated lipids
Diarrhea D003967 32 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Graft Occlusion, Vascular D006083 11 associated lipids
Hypercalcemia D006934 13 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with tacrolimus

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with tacrolimus?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with tacrolimus?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with tacrolimus?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with tacrolimus?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with tacrolimus?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with tacrolimus

Download all related citations
Per page 10 20 50 100 | Total 15051
Authors Title Published Journal PubMed Link
Jungersted JM et al. Effects of topical corticosteroid and tacrolimus on ceramides and irritancy to sodium lauryl sulphate in healthy skin. 2011 Acta Derm. Venereol. pmid:21365172
Quist SR et al. Effects of Topical Tacrolimus and Polyunsaturated Fatty Acids on In Vivo Release of Eicosanoids in Atopic Dermatitis During Dermal Microdialysis. 2016 Acta Derm. Venereol. pmid:26911315
Zattra E et al. Labial melanotic macule after application of topical tacrolimus: two case reports. 2010 Acta Derm. Venereol. pmid:20814635
Hartmann A et al. Treatment of generalised vitiligo with tacrolimus 0.1% ointment vs. UVB intense pulsed light phototherapy: a pilot study. 2014 Acta Derm. Venereol. pmid:24473666
Granlund H et al. Treatment of lichenified atopic eczema with tacrolimus ointment. 2001 Aug-Sep Acta Derm. Venereol. pmid:11720192
Pagliarello C and Paradisi A Topical tacrolimus is useful for avoiding suction-blister epidermal grafting depigmentation in non-segmental vitiligo: a case report. 2012 Acta Derm. Venereol. pmid:22101735
Hamade Y et al. Lichen planus in childhood showing various cutaneous features. 2012 Acta Derm. Venereol. pmid:22101991
Mandelin J et al. Leg ulcers treated with topical tacrolimus in patients with rheumatoid arthritis. 2010 Acta Derm. Venereol. pmid:21057750
Nakamizo S et al. Treatment of neuropathic itch possibly due to trigeminal trophic syndrome with 0.1% topical tacrolimus and gabapentin. 2010 Acta Derm. Venereol. pmid:21057761
Mandelin J et al. One-year treatment with 0.1% tacrolimus ointment versus a corticosteroid regimen in adults with moderate to severe atopic dermatitis: A randomized, double-blind, comparative trial. 2010 Acta Derm. Venereol. pmid:20169301
Ujiie H et al. Successful treatment of nail lichen planus with topical tacrolimus. 2010 Acta Derm. Venereol. pmid:20169322
Pitarch G et al. Systemic absorption of topical tacrolimus in Pyoderma gangrenosum. 2006 Acta Derm. Venereol. pmid:16585995
Cunha PR Pimecrolimus cream 1% is effective in seborrhoeic dermatitis refractory to treatment with topical corticosteroids. 2006 Acta Derm. Venereol. pmid:16585998
Cunha PR and Rossi AB Pimecrolimus cream 1% is effective in a case of granulomatous rosacea. 2006 Acta Derm. Venereol. pmid:16585999
Chittock J et al. Comparing the Effect of a Twice-weekly Tacrolimus and Betamethasone Valerate Dose on the Subclinical Epidermal Barrier Defect in Atopic Dermatitis. 2015 Acta Derm. Venereol. pmid:25594610
Pagliarello C et al. Topical tacrolimus and 50% zinc oxide paste for Hailey-Hailey disease: less is more. 2012 Acta Derm. Venereol. pmid:22293917
Kim TW et al. Proactive treatment of adult facial seborrhoeic dermatitis with 0.1% tacrolimus ointment: randomized, double-blind, vehicle-controlled, multi-centre trial. 2013 Acta Derm. Venereol. pmid:23388687
Jedlicková H et al. Granuloma faciale successfully treated with topical tacrolimus: a case report. 2008 Acta Dermatovenerol Alp Pannonica Adriat pmid:18454269
Thaçi D and Salgo R The topical calcineurin inhibitor pimecrolimus in atopic dermatitis: a safety update. 2007 Acta Dermatovenerol Alp Pannonica Adriat pmid:17992459
Vukićević J et al. Unilateral multiple lichen striatus treated with tacrolimus ointment: a case report. 2009 Acta Dermatovenerol Alp Pannonica Adriat pmid:19350187