Kuo CJ et al. |
Rapamycin selectively inhibits interleukin-2 activation of p70 S6 kinase. |
1992 |
Nature |
pmid:1614535
|
Thomson AW et al. |
FK 506, cardiac transplantation, and graft-vessel disease. |
1992 |
Lancet |
pmid:1370563
|
Takahara S et al. |
The in vitro immunosuppressive effect of deoxymethylspergualin in man as compared with FK506 and cyclosporine. |
1992 |
Transplantation |
pmid:1373537
|
Johnson MC et al. |
QT prolongation and Torsades de Pointes after administration of FK506. |
1992 |
Transplantation |
pmid:1373538
|
Kim YI et al. |
Stimulation of liver regeneration by pretreatment with azathioprine as well as cyclosporine and FK506. |
1992 |
Transplantation |
pmid:1373539
|
Carobbi A et al. |
Synergism of splenectomy and immunosuppressive drugs in prolongation of cardiac xenograft survival. |
1992 |
Transplant. Proc. |
pmid:1373543
|
Yamada K et al. |
New morphological changes induced by FK506 in a short period in the rat kidney and the effect of superoxide dismutase and OKY-046 on THEM: the relationship of FK506 nephrotoxicity to lipid peroxidation and change in production of thromboxane A2 in the kidney. |
1992 |
Transpl. Int. |
pmid:14621878
|
Tai PK et al. |
Association of a 59-kilodalton immunophilin with the glucocorticoid receptor complex. |
1992 |
Science |
pmid:1376003
|
Jegasothy BV et al. |
Tacrolimus (FK 506)--a new therapeutic agent for severe recalcitrant psoriasis. |
1992 |
Arch Dermatol |
pmid:1376102
|
Wiederrecht G et al. |
Isolation of a human cDNA encoding a 25 kDa FK-506 and rapamycin binding protein. |
1992 |
Biochem. Biophys. Res. Commun. |
pmid:1376117
|
Mor E et al. |
Late-onset acute rejection in orthotopic liver transplantation--associated risk factors and outcome. |
1992 |
Transplantation |
pmid:1279849
|
Hirano Y et al. |
The effects of FK506 and cyclosporine on the exocrine function of the rat pancreas. |
1992 |
Transplantation |
pmid:1279850
|
Takaya S et al. |
Liver transplantation in positive cytotoxic crossmatch cases using FK506, high-dose steroids, and prostaglandin E1. |
1992 |
Transplantation |
pmid:1279851
|
Renoir JM et al. |
[Effect of immunosuppressants FK506 and rapamycin on the function of progesterone receptor: protein "p59-HBI", intersection between immunology and endocrinology?]. |
1992 |
C. R. Acad. Sci. III, Sci. Vie |
pmid:1284044
|
Natazuka T |
FK506 reverses adriamycin resistance in a multidrug-resistant human leukemia cell line. |
1992 |
Kobe J Med Sci |
pmid:1284834
|
Tocci MJ and Sigal NH |
Recent advances in the mechanism of action of cyclosporine and FK506. |
1992 |
Curr. Opin. Nephrol. Hypertens. |
pmid:1285380
|
Bavandi A et al. |
Diet-induced dermatitis response of hairless rats to systemic treatment with cyclosporin A (Sandimmun), cyclosporin H and FK506. |
1992 |
Exp. Dermatol. |
pmid:1285411
|
Iwasaki K et al. |
Effect of repeated oral doses of a novel immunosuppressive macrolide lactone on hepatic mixed-function oxidase system in the rat. Comparative study with ciclosporin. |
1992 |
Arzneimittelforschung |
pmid:1379812
|
Takada K et al. |
Distribution kinetics of FK-506, a novel immunosuppressant, after intravenous administration to rats in comparison with cyclosporin A. |
1992 |
Biopharm Drug Dispos |
pmid:1379839
|
Christians U et al. |
Specific and sensitive measurement of FK506 and its metabolites in blood and urine of liver-graft recipients. |
1992 |
Clin. Chem. |
pmid:1382896
|
Fruman DA et al. |
Correlation of calcineurin phosphatase activity and programmed cell death in murine T cell hybridomas. |
1992 |
Eur. J. Immunol. |
pmid:1382988
|
Mittrücker HW and Fleischer B |
Functional localization of an exocytosis-triggering G-protein in human cytotoxic T lymphocytes. |
1992 |
Immunology |
pmid:1383135
|
Wang SC et al. |
FK-506 inhibits proliferation and IL-4 messenger RNA production by a T-helper 2 cell line. |
1992 |
J. Surg. Res. |
pmid:1383612
|
Jordan ML et al. |
Initial studies with FK506 in renal transplantation. |
1991 Sep-Oct |
Cleve Clin J Med |
pmid:1718631
|
Siekierka JJ et al. |
Potential roles of other FK 506-binding proteins in mediating the effects of FK 506. |
1991 |
Transplant. Proc. |
pmid:1721256
|
Morris RE |
In vivo immunopharmacology of the macrolides FK 506 and rapamycin: toward the era of rational immunosuppressive drug discovery, development, and use. |
1991 |
Transplant. Proc. |
pmid:1721257
|
Kobayashi M et al. |
FK 506 assay past and present--characteristics of FK 506 ELISA. |
1991 |
Transplant. Proc. |
pmid:1721258
|
Warty VS et al. |
Practical aspects of FK 506 analysis (Pittsburgh experience). |
1991 |
Transplant. Proc. |
pmid:1721259
|
Jusko WJ and D'Ambrosio R |
Monitoring FK 506 concentrations in plasma and whole blood. |
1991 |
Transplant. Proc. |
pmid:1721260
|
Venkataramanan R et al. |
Pharmacokinetics of FK 506 in transplant patients. |
1991 |
Transplant. Proc. |
pmid:1721261
|
Christians U et al. |
High performance liquid chromatography/mass spectrometry of FK 506 and its metabolites in blood, bile, and urine of liver grafted patients. |
1991 |
Transplant. Proc. |
pmid:1721262
|
Blanc P et al. |
Antiproliferative effect of FK 506 and cyclosporine on adult human hepatocytes in culture. |
1991 |
Transplant. Proc. |
pmid:1721288
|
Loréal O et al. |
FK 506 is less cytotoxic than cyclosporine to human and rat hepatocytes in vitro. |
1991 |
Transplant. Proc. |
pmid:1721289
|
McCauley J et al. |
Cyclosporine and FK 506 induced inhibition of renal epithelial cell proliferation. |
1991 |
Transplant. Proc. |
pmid:1721290
|
McLachlan G et al. |
Growth inhibition of the MOLT-4 human T-leukemia cell line. A comparison of cyclosporine and FK 506. |
1991 |
Transplant. Proc. |
pmid:1721291
|
Akselband Y et al. |
Rapamycin inhibits spontaneous and fibroblast growth factor beta-stimulated proliferation of endothelial cells and fibroblasts. |
1991 |
Transplant. Proc. |
pmid:1721292
|
Schreiber SL et al. |
Immunophilin-ligand complexes as probes of intracellular signaling pathways. |
1991 |
Transplant. Proc. |
pmid:1721293
|
Chen-Woan M et al. |
Diminished lymphocyte growth from endomyocardial biopsies from cardiac transplant patients on FK 506 immunosuppression. |
1991 |
Transplant. Proc. |
pmid:1721320
|
Fukuzawa M et al. |
Effect of FK 506 on CD4+ and CD8+ T-cell function in vivo. |
1991 |
Transplant. Proc. |
pmid:1721321
|
Takaori K et al. |
Effects of FK 506 on in vivo immunity in comparison to cyclosporine. |
1991 |
Transplant. Proc. |
pmid:1721322
|
Jordan ML et al. |
Inhibition of T-cell function by FK 506 and cyclosporine is not accompanied by alterations in intracellular calcium. |
1991 |
Transplant. Proc. |
pmid:1721323
|
Motta I et al. |
FK 506 favors the generation of memory T cells in vitro. |
1991 |
Transplant. Proc. |
pmid:1721324
|
Nakata S et al. |
Immunosuppressive effect of FK 506 on cytotoxic T lymphocytes and delayed-type hypersensitivity in rats. |
1991 |
Transplant. Proc. |
pmid:1721325
|
Cooper MH et al. |
Evaluation of the influence of FK 506, rapamycin, and cyclosporine on processing and presentation of particulate antigen by macrophages: assessment of a drug "carry-over" effect. |
1991 |
Transplant. Proc. |
pmid:1721326
|
Green M et al. |
Infectious complications of pediatric liver transplantation under FK 506. |
1991 |
Transplant. Proc. |
pmid:1721352
|
Carroll PB et al. |
Effect of the immunosuppressant FK506 on glucose-induced insulin secretion from adult rat islets of Langerhans. |
1991 |
Transplantation |
pmid:1702911
|
Torre-Cisneros J et al. |
The spectrum of aspergillosis in liver transplant patients: comparison of FK 506 and cyclosporine immunosuppression. |
1991 |
Transplant. Proc. |
pmid:1721353
|
Starzl TE et al. |
Hepatotrophic effects of FK506 in dogs. |
1991 |
Transplantation |
pmid:1702912
|
Paul AA et al. |
CMV retinitis and the use of FK 506. |
1991 |
Transplant. Proc. |
pmid:1721354
|
Keicho N et al. |
Effects of an immunosuppressant, FK506, on interleukin 1 alpha production by human macrophages and a macrophage-like cell line, U937. |
1991 |
Cell. Immunol. |
pmid:1703047
|
Reyes J et al. |
Posttransplant lymphoproliferative disorders occurring under primary FK 506 immunosuppression. |
1991 |
Transplant. Proc. |
pmid:1721355
|
White DJ |
FK506: the promise and the paradox. |
1991 |
Clin. Exp. Immunol. |
pmid:1703053
|
Whiteside TL et al. |
Serial monitoring of immunologic function and phenotype of lymphocytes in the blood of transplanted patients randomized to cyclosporine or FK 506. |
1991 |
Transplant. Proc. |
pmid:1721356
|
Frayha HH et al. |
Lymphoproliferative disorder in a liver transplant patient on FK 506. |
1991 |
Lancet |
pmid:1703258
|
Van Thiel DH et al. |
Interferon therapy of hepatitis following liver transplantation under FK 506 or cyclosporine. |
1991 |
Transplant. Proc. |
pmid:1721357
|
Burman K and Crawford DH |
Effect of FK 506 on Epstein-Barr virus specific cytotoxic T cells. |
1991 |
Lancet |
pmid:1703259
|
McCauley J et al. |
Changes in renal function after liver transplantation under FK 506. |
1991 |
Transplant. Proc. |
pmid:1721385
|
Tauxe WN et al. |
A comparison of the renal effects (ERPF, GFR, and FF) of FK 506 and cyclosporine in patients with liver transplantation. |
1991 |
Transplant. Proc. |
pmid:1721386
|
McCauley J et al. |
Renal function after conversion from cyclosporine to FK 506 in liver transplant patients. |
1991 |
Transplant. Proc. |
pmid:1721387
|
Hossein-Nia M et al. |
Urinary proteins as a marker of drug-induced renal damage following treatment with cyclosporine or FK 506. |
1991 |
Transplant. Proc. |
pmid:1721388
|
Winkler M et al. |
Association of elevated FK 506 plasma levels with nephrotoxicity in liver-grafted patients. |
1991 |
Transplant. Proc. |
pmid:1721389
|
Schmidt RJ et al. |
Hemolytic-uremic syndrome in a renal transplant recipient on FK 506 immunosuppression. |
1991 |
Transplant. Proc. |
pmid:1721390
|
Tze WJ et al. |
Effect of FK 506 on glucose metabolism and insulin secretion in normal rats. |
1991 |
Transplant. Proc. |
pmid:1721391
|
Fukuzaki T et al. |
Induction of tolerance to islet allografts with preoperative donor spleen cell injection and a short course of FK 506 treatment. |
1991 |
Transplant. Proc. |
pmid:1721415
|
Tzakis AG et al. |
FK 506 rescue in chronic graft-versus-host-disease after bone marrow transplantation. |
1991 |
Transplant. Proc. |
pmid:1721416
|
Masaoka T et al. |
Phase II study of FK 506 for allogeneic bone marrow transplantation. |
1991 |
Transplant. Proc. |
pmid:1721417
|
Markus PM et al. |
The effect of cyclosporine, rapamycin and FK 506 the survival following allogeneic bone marrow transplantation. |
1991 |
Transplant. Proc. |
pmid:1721418
|
Cooper MH et al. |
The induction of pseudo-graft-versus-host disease following syngeneic bone marrow transplantation using FK 506. |
1991 |
Transplant. Proc. |
pmid:1721419
|
Boggs S et al. |
FK 506 has no short-term effects on endogenous or exogenous myeloid reconstitution in irradiated mice. |
1991 |
Transplant. Proc. |
pmid:1721420
|
Cooper MH et al. |
Prolonged prevention of acute graft-versus-host disease after allogeneic bone marrow transplantation by donor pretreatment using FK 506. |
1991 |
Transplant. Proc. |
pmid:1721421
|
Van Duyne GD et al. |
Atomic structure of FKBP-FK506, an immunophilin-immunosuppressant complex. |
1991 |
Science |
pmid:1709302
|
Lim SM and White DJ |
The pharmacology of immunosuppression. |
1991 |
Ann. Acad. Med. Singap. |
pmid:1709344
|
Rosen MK et al. |
Proton and nitrogen sequential assignments and secondary structure determination of the human FK506 and rapamycin binding protein. |
1991 |
Biochemistry |
pmid:1709363
|
Sakr MF et al. |
FK 506 ameliorates the hepatic injury associated with ischemia and reperfusion in rats. |
1991 |
Hepatology |
pmid:1709412
|
Hohlfeld R |
[Current therapy of multiple sclerosis: value of cyclosporin A and FK 506]. |
1991 |
Nervenarzt |
pmid:1709725
|
Kay JE et al. |
Inhibition of T and B lymphocyte proliferation by rapamycin. |
1991 |
Immunology |
pmid:1709916
|
Ringe D |
Immunosuppression. Binding by design. |
1991 |
Nature |
pmid:1710317
|
Fabrega AJ et al. |
FK 506 enhances the beneficial effects of donor-specific blood transfusion on allograft survival in rats. |
1991 |
Transplant. Proc. |
pmid:1721447
|
Davies CB et al. |
Effects of donor-specific transfusion, cyclosporine A and FK 506 on rat cardiac allograft survival. |
1991 |
Transplant. Proc. |
pmid:1721448
|
Abu-Elmagd K et al. |
FK 506: a new therapeutic agent for severe recalcitrant psoriasis. |
1991 |
Transplant. Proc. |
pmid:1721449
|
Nikolaidis NL et al. |
Metabolic effects of FK 506 in patients with severe psoriasis: short-term follow-up of seven cases. |
1991 |
Transplant. Proc. |
pmid:1721450
|
Abu-Elmagd K et al. |
Efficacy of FK 506 in the treatment of recalcitrant pyoderma gangrenosum. |
1991 |
Transplant. Proc. |
pmid:1721451
|
Thomson AW et al. |
Influence of FK 506 on T lymphocytes, Langerhans' cells and the expression of cytokine receptors and adhesion molecules in psoriatic skin lesions: a preliminary study. |
1991 |
Transplant. Proc. |
pmid:1721452
|
Jin YJ et al. |
Molecular cloning of a membrane-associated human FK506- and rapamycin-binding protein, FKBP-13. |
1991 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:1713687
|
Murase N et al. |
Long survival in rats after multivisceral versus isolated small-bowel allotransplantation under FK 506. |
1991 |
Surgery |
pmid:1714104
|
Lodish HF and Kong N |
Cyclosporin A inhibits an initial step in folding of transferrin within the endoplasmic reticulum. |
1991 |
J. Biol. Chem. |
pmid:1714445
|
Ellis D et al. |
Phospholipase-C and Na-K ATPase activation by cyclosporine and FK506 in LLC-PK1, cells. Possible implications in blood pressure regulation. |
1991 |
Transplantation |
pmid:1714643
|
Simmons RL and Wang SC |
New horizons in immunosuppression. |
1991 |
Transplant. Proc. |
pmid:1714645
|
Calne RY |
Immunosuppression for organ grafting. |
1991 |
Transplant. Proc. |
pmid:1714646
|
Ochiai T et al. |
[Immunosuppressive agents--advances of the developmental studies and the mode of action]. |
1991 |
Nippon Rinsho |
pmid:1715926
|
Ricordi C et al. |
In vivo effect of FK506 on human pancreatic islets. |
1991 |
Transplantation |
pmid:1716797
|
Katz IA et al. |
Comparison of the effects of FK506 and cyclosporine on bone mineral metabolism in the rat. A pilot study. |
1991 |
Transplantation |
pmid:1716801
|
Jiang H et al. |
Effect of FK-506 on heart allograft survival in the highly sensitized recipient rats as compared with ciclosporin and 15-deoxyspergualin. |
1991 |
Eur Surg Res |
pmid:1723683
|
Pezze JL and Whiteman K |
Transplantation's newest weapon FK 506. |
1991 |
Am J Nurs |
pmid:1716857
|
Fung JJ et al. |
Conversion of liver allograft recipients from cyclosporine to FK 506-based immunosuppression: benefits and pitfalls. |
1991 |
Transplant. Proc. |
pmid:1703682
|
Marquis-Omer D et al. |
Stabilization of the FK506 binding protein by ligand binding. |
1991 |
Biochem. Biophys. Res. Commun. |
pmid:1716886
|
Wu J et al. |
Comparative immunoregulatory effects of rapamycin, FK 506 and cyclosporine on mitogen-induced cytokine production and lymphoproliferation. |
1991 |
Transplant. Proc. |
pmid:1703683
|
Sakai K et al. |
[The effect of a new immunosuppressive agent, FK-506, on xenogeneic neural transplantation in rodents--comparison with cyclosporin A]. |
1991 |
No To Shinkei |
pmid:1716937
|
Yoshimura R et al. |
A comparative study between cyclosporine and FK 506 effects on renal microsomal P-450. |
1991 |
Transplant. Proc. |
pmid:1703686
|
Miyagawa S et al. |
Mechanism of unresponsiveness in rats induced by a short course of FK 506 or CyA. |
1991 |
Transplant. Proc. |
pmid:1703687
|