| MeSH term | MeSH ID | Detail |
|---|---|---|
| Polyomavirus Infections | D027601 | 1 associated lipids |
| Lymphohistiocytosis, Hemophagocytic | D051359 | 1 associated lipids |
| Rheumatoid Nodule | D012218 | 1 associated lipids |
| Hernia, Ventral | D006555 | 1 associated lipids |
| Hepatitis, Autoimmune | D019693 | 1 associated lipids |
| Moyamoya Disease | D009072 | 1 associated lipids |
| Apraxias | D001072 | 1 associated lipids |
| Hypertensive Encephalopathy | D020343 | 1 associated lipids |
| Hearing Loss, Bilateral | D006312 | 1 associated lipids |
| Nocturia | D053158 | 1 associated lipids |
tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- Am. J. Physiol. Renal Physiol. (1)
- Drug Metab. Dispos. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Weng LC et al. | Association between use of FK506 and prevalence of post-transplantation diabetes mellitus in kidney transplant patients. | 2014 | Transplant. Proc. | pmid:24656004 |
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| Wang SS et al. | Clinical experience of tacrolimus with everolimus in heart transplantation. | 2012 | Transplant. Proc. | pmid:22564581 |
| Morphological characteristics of renal allografts showing renal dysfunction under FK 506 therapy: is graft biopsy available to reveal the morphological findings corresponding with FK 506 nephropathy? Japanese FK 506 Study Group. | 1993 | Transplant. Proc. | pmid:7679824 | |
| Kato H et al. | Spontaneous proliferation of peripheral blood mononuclear cells as an indicator for insufficient plasma levels of FK 506 in the early phase after liver transplantation. | 1994 | Transplant. Proc. | pmid:7513481 |
| Morris RE | In vivo immunopharmacology of the macrolides FK 506 and rapamycin: toward the era of rational immunosuppressive drug discovery, development, and use. | 1991 | Transplant. Proc. | pmid:1721257 |
| Loss M et al. | Glucose and lipid metabolism in liver transplant patients under long-term tacrolimus (FK 506) monotherapy. | 1996 | Transplant. Proc. | pmid:8623210 |
| Millis JM et al. | Successful use of tacrolimus for initial rejection episodes after liver transplantation. | 1998 | Transplant. Proc. | pmid:9636569 |
| Ichikawa Y et al. | Acute rejection and the therapeutic choice of drug. | 2000 | Transplant. Proc. | pmid:11119923 |
| Platz KP et al. | FK506 for primary and rescue therapy following liver transplantation. | 1998 | Transplant. Proc. | pmid:9636570 |
| Jang HJ et al. | Tacrolimus for rescue therapy in refractory renal allograft rejection. | 2000 | Transplant. Proc. | pmid:11119925 |
| Morita H et al. | Acceptance of skin xenografts (from guinea pig to mice) by portal venous and intravenous injections of donor hematolymphoid cells. | 2000 | Transplant. Proc. | pmid:10715422 |
| Gentil MA et al. | Effect of new immunosuppressive regimens on cost of renal transplant maintenance immunosuppression. | 2005 | Transplant. Proc. | pmid:15866631 |
| Garcia-Donaire JA et al. | Tacrolimus as basic immunosuppression in pregnancy after renal transplantation. A single-center experience. | 2005 | Transplant. Proc. | pmid:16386528 |
| Argudo A et al. | Liver Transplant Patient Carriers of Polymorphism Cyp3a5*1 Donors May Need More Doses of Tacrolimus From the First Month After Transplantation. | 2015 | Transplant. Proc. | pmid:26518936 |
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| Cuñetti L et al. | Chronic Pain Treatment With Cannabidiol in Kidney Transplant Patients in Uruguay. | 2018 | Transplant. Proc. | pmid:29579828 |
| Armenta Bautista A et al. | Renal Transplantation in Second-Level Private Hospitals in the State of Mexico. | 2018 | Transplant. Proc. | pmid:29579825 |
| McCauley J et al. | Cyclosporine and FK 506 induced inhibition of renal epithelial cell proliferation. | 1991 | Transplant. Proc. | pmid:1721290 |
| Ciancio G et al. | Human donor bone marrow cells can enhance hyporeactivity in renal transplantation using maintenance FK 506 and OKT3 induction therapy. | 1996 | Transplant. Proc. | pmid:8623473 |
| Gruessner RW | Antibody induction therapy in pancreas transplantation. | 1998 | Transplant. Proc. | pmid:9636632 |
| Moffatt SD et al. | Comparative efficacy of liposomal FK 506 with FK 506 (tacrolimus) with and without anti-CD4/CD8 monoclonal antibodies. | 1999 | Transplant. Proc. | pmid:10578277 |
| Hampel G et al. | Different effects of cyclosporine and tacrolimus on the activation of mesangial metalloproteinases and their inhibitors. | 1999 | Transplant. Proc. | pmid:10578279 |
| Burg M et al. | Enteric-coated mycophenolate sodium reduces gastrointestinal symptoms in renal transplant patients. | 2009 | Transplant. Proc. | pmid:20005359 |
| Falkiewicz K et al. | Influence of vitamin D receptor gene polymorphisms on secondary hyperparathyroidism and bone density after kidney transplantation. | 2005 | Transplant. Proc. | pmid:15848611 |
| Yang S et al. | Characteristics of long-term immunosuppressive therapy in Chinese pediatric renal transplant patients: a single-center experience. | 2009 | Transplant. Proc. | pmid:20005361 |
| Hohage H et al. | Cyclosporine and tacrolimus: influence on cardiovascular risk factors. | 2005 | Transplant. Proc. | pmid:15848615 |
| Kantarci G et al. | Effects of different calcineurin inhibitors on sex hormone levels in transplanted male patients. | 2004 Jan-Feb | Transplant. Proc. | pmid:15013339 |
| Yamazaki R et al. | Interindividual variation of maximal blood levels of tacrolimus after its oral administration in hematopoietic cell transplant recipients. | 2009 | Transplant. Proc. | pmid:19545738 |
| Nassar CA et al. | Effects of long-term FK 506 therapy on the alveolar bone and cementum of rats. | 2009 | Transplant. Proc. | pmid:19545747 |
| Platz KP et al. | Indications for mycofenolate mofetil therapy after liver transplantation. | 1997 | Transplant. Proc. | pmid:9365601 |
| Kolonko A et al. | Improved kidney graft function after conversion from twice daily tacrolimus to a once daily prolonged-release formulation. | 2011 | Transplant. Proc. | pmid:21996198 |
| Imai K et al. | Pancreaticoduodenal allotransplantation with the use of FK 506, cyclosporine, and triple-regimen immunosuppression. | 1990 | Transplant. Proc. | pmid:1697117 |
| Demirbas A et al. | FK 506 in simultaneous pancreas/kidney transplantation: the University of Miami experience. | 1997 | Transplant. Proc. | pmid:9365608 |
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| Iga C et al. | Prolonged survival of small intestinal allograft in the rat with cyclosporine A, FK 506, and 15-deoxyspergualin. | 1990 | Transplant. Proc. | pmid:1697118 |
| Reyes J et al. | Lymphoproliferative disease after intestinal transplantation under primary FK 506 immunosuppression. | 1994 | Transplant. Proc. | pmid:7518137 |
| Murase N et al. | Small bowel transplantation in sensitized recipients: comparison with heart, kidney, and liver grafts. | 1994 | Transplant. Proc. | pmid:7518139 |
| Meiser BM et al. | Simvastatin decreases accelerated graft vessel disease after heart transplantation in an animal model. | 1993 | Transplant. Proc. | pmid:7682363 |
| O'Rourke M et al. | Recovery of delayed-type hypersensitivity following liver transplantation. | 1995 | Transplant. Proc. | pmid:7533369 |
| Yu Y et al. | Mutagenicity of the new immunosuppressive drugs, FK 506, and spergualin. | 1993 | Transplant. Proc. | pmid:7682364 |
| Gaweco AS et al. | Common and sequential overexpression patterns of T-helper cytokines during acute (cellular) rejection, and correlation of proinflammatory cytokine expression with chronic (ductopenic) rejection of human liver allografts: a study under cyclosporine, FK 506, and quadruple BT 563 immunosuppression. | 1995 | Transplant. Proc. | pmid:7533370 |
| Fukuzawa M et al. | Effect of FK 506 on CD4+ and CD8+ T-cell function in vivo. | 1991 | Transplant. Proc. | pmid:1721321 |
| Takaori K et al. | Effects of FK 506 on in vivo immunity in comparison to cyclosporine. | 1991 | Transplant. Proc. | pmid:1721322 |
| Waller JR et al. | Effect of rapamycin in combination with calcineurin inhibitors, FK506 and cyclosporin, following arterial injury. | 2002 | Transplant. Proc. | pmid:12176449 |
| Wilson C et al. | Evaluation of daclizumab to reduce delayed graft function in non-heart-beating renal transplantation: a prospective, randomized trial. | 2005 | Transplant. Proc. | pmid:15919462 |
| Tzakis AG et al. | Campath-1H in intestinal and multivisceral transplantation: preliminary data. | 2002 | Transplant. Proc. | pmid:12034248 |
| Izutani H et al. | Graft coronary arteriosclerosis in rat heart transplant model with FK 506 short-term administration. | 1995 | Transplant. Proc. | pmid:7533425 |
| Aktürk S et al. | Average Tacrolimus Trough Level in the First Month After Transplantation May Predict Acute Rejection. | 2017 | Transplant. Proc. | pmid:28340806 |
| Torre-Cisneros J et al. | The spectrum of aspergillosis in liver transplant patients: comparison of FK 506 and cyclosporine immunosuppression. | 1991 | Transplant. Proc. | pmid:1721353 |
| Sasaki K et al. | Effect of FK 506 and splenectomy on orthotopic small bowel xenotransplantation in the hamster-to-rat animal models. | 1998 | Transplant. Proc. | pmid:9838521 |
| Takayama J et al. | Living related liver transplantation in patients with ABO incompatibility. | 1998 | Transplant. Proc. | pmid:9838537 |
| Scott JS et al. | Tacrolimus: a cause of hypertrophic cardiomyopathy in pediatric heart transplant recipients? | 1999 Feb-Mar | Transplant. Proc. | pmid:10083017 |
| Herrero JI et al. | Conversion from calcineurin inhibitors to mycophenolate mofetil in liver transplant recipients with diabetes mellitus. | 2003 | Transplant. Proc. | pmid:12962832 |
| Lama R et al. | Lung transplants with tacrolimus and mycophenolate mofetil: a review. | 2003 | Transplant. Proc. | pmid:12962866 |
| Marino IR et al. | Preoperative assessment of risk in liver transplantation: a multivariate analysis in 2376 cases of the UW era. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123079 |
| Rayes N et al. | Distribution of lymphocyte subtypes in liver transplant recipients. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123103 |
| Alessiani M et al. | Intestinal transplantation with and without the colon in FK 506 immunosuppressed pigs. | 1996 | Transplant. Proc. | pmid:8908021 |
| Youseff N and Small S | A retrospective analysis of a sirolimus/prograf regimen for the prevention of acute rejection in recipients of primary mismatched renal allografts. | 2002 | Transplant. Proc. | pmid:12176522 |
| Asfar S et al. | Small bowel transplantation. | 1996 | Transplant. Proc. | pmid:8908039 |
| Campos HH and Abbud Filho M | One-year follow-up of a Brazilian randomized multicenter study comparing tacrolimus versus cyclosporine in kidney transplantation. | 2002 | Transplant. Proc. | pmid:12176523 |
| Nozaki S et al. | Effect of brequinar sodium on accelerated cardiac allograft rejection in presensitized recipients. | 1994 | Transplant. Proc. | pmid:7520633 |
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| Tauxe WN et al. | A comparison of the renal effects (ERPF, GFR, and FF) of FK 506 and cyclosporine in patients with liver transplantation. | 1991 | Transplant. Proc. | pmid:1721386 |
| Marcus EA et al. | Successful term pregnancy in an intestine-pancreas transplant recipient with chronic graft dysfunction and parenteral nutrition dependence: a case report. | 2015 | Transplant. Proc. | pmid:25724255 |
| Yoshimura N et al. | A new immunosuppressive agent, FK506, inhibits the expression of alloantigen-activated suppressor cells as well as the induction of alloreactivity. | 1989 | Transplant. Proc. | pmid:2468202 |
| McCauley J et al. | Renal function after conversion from cyclosporine to FK 506 in liver transplant patients. | 1991 | Transplant. Proc. | pmid:1721387 |
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| Balbontin FG et al. | Tacrolimus monitoring by simplified sparse sampling under the concentration time curve. | 2003 | Transplant. Proc. | pmid:14611982 |
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| Tzakis AG et al. | FK 506 rescue in chronic graft-versus-host-disease after bone marrow transplantation. | 1991 | Transplant. Proc. | pmid:1721416 |
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| Deleuze S et al. | New onset dyslipidemia after renal transplantation: is there a difference between tacrolimus and cyclosporine? | 2006 | Transplant. Proc. | pmid:16980075 |
| Braun F et al. | Living-related versus living-unrelated kidney transplantation using tacrolimus initial immunosuppression. | 2000 | Transplant. Proc. | pmid:10700989 |
| Finni PE et al. | Is hepatitis C a risk factor to posttransplant diabetes mellitus after renal transplantation in patients using tacrolimus? | 2004 | Transplant. Proc. | pmid:15194303 |
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