tacrolimus

Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.

Cross Reference

Introduction

To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with tacrolimus?

tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with tacrolimus

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Uremia D014511 33 associated lipids
Colitis, Ulcerative D003093 24 associated lipids
Stomach Ulcer D013276 75 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Nocardia Infections D009617 6 associated lipids
Diarrhea D003967 32 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Graft Occlusion, Vascular D006083 11 associated lipids
Hypercalcemia D006934 13 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with tacrolimus

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with tacrolimus?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with tacrolimus?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with tacrolimus?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with tacrolimus?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with tacrolimus?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with tacrolimus

Download all related citations
Per page 10 20 50 100 | Total 15051
Authors Title Published Journal PubMed Link
Banovic F et al. Tacrolimus therapy for dermal arteritis of the nasal philtrum refractory to surgery and anti-inflammatory therapy (doxycycline/niacinamide and topical fluocinolone) in a dog. 2018 Vet. Dermatol. pmid:28990239
Banovic F et al. Therapeutic effectiveness of calcineurin inhibitors in canine vesicular cutaneous lupus erythematosus. 2017 Vet. Dermatol. pmid:28439997
Lehner GM and Linek M A case of vesicular cutaneous lupus erythematosus in a Border collie successfully treated with topical tacrolimus and nicotinamide-tetracycline. 2013 Vet. Dermatol. pmid:24118370
Bensignor E and Olivry T Treatment of localized lesions of canine atopic dermatitis with tacrolimus ointment: a blinded randomized controlled trial. 2005 Vet. Dermatol. pmid:15725106
Scholz FM et al. Focal metatarsal fistulae syndrome affecting a greyhound dog successfully treated with topical 0.1% tacrolimus ointment. 2015 Vet. Dermatol. pmid:26216245
Nell B et al. The effect of topical pimecrolimus on keratoconjunctivitis sicca and chronic superficial keratitis in dogs: results from an exploratory study. 2005 Jan-Feb Vet Ophthalmol pmid:15644099
Berdoulay A et al. Effect of topical 0.02% tacrolimus aqueous suspension on tear production in dogs with keratoconjunctivitis sicca. 2005 Jul-Aug Vet Ophthalmol pmid:16008701
Hafizi S et al. Differential effects of rapamycin, cyclosporine A, and FK506 on human coronary artery smooth muscle cell proliferation and signalling. 2004 May-Jun Vascul. Pharmacol. pmid:15607500
Dissemond J et al. Successful treatment of stasis dermatitis with topical tacrolimus. 2004 VASA pmid:15623206
Woodward RS et al. The long-term outcomes and costs of diabetes mellitus among renal transplant recipients: tacrolimus versus cyclosporine. 2011 Value Health pmid:21315636
Christ B et al. Interactions of sildenafil and tacrolimus in men with erectile dysfunction after kidney transplantation. 2001 Urology pmid:11597545
Harmon JD et al. Stuttering priapism in a liver transplant patient with toxic levels of fk506. 1999 Urology pmid:10754131
Chkhotua AB et al. Kidney transplantation from living-unrelated donors: comparison of outcome with living-related and cadaveric transplants under current immunosuppressive protocols. 2003 Urology pmid:14665344
Ebert AK et al. [Topical therapy of balanitis xerotica obliterans in childhood. Long-term clinical results and an overview]. 2007 Urologe A pmid:17994212
[Tacrolimus--a new perspective in kidney transplantation]. 1996 Urologe A pmid:9022401
Nomura T et al. Enhancement by cyclosporin A of taxol-induced apoptosis of human urinary bladder cancer cells. 2002 Urol. Res. pmid:12086014
Hwang MT and Goldfarb DS Uric acid stones following hepatic transplantation. 2004 Urol. Res. pmid:15565437
Veroux P et al. Severe neurotoxicity in tacrolimus-treated living kidney transplantation in two cases. 2003 Urol. Int. pmid:14646448
Pichler R et al. De novo renal cell carcinoma in a kidney allograft with focus on contrast-enhanced ultrasound. 2014 Urol. Int. pmid:25115614
Naderi GH et al. Tacrolimus rescue therapy for corticosteroid-resistant and polyclonal antibody-resistant kidney allograft rejections. 2009 Urol J pmid:19241339