tacrolimus

Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.

Cross Reference

Introduction

To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with tacrolimus?

tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with tacrolimus

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Uremia D014511 33 associated lipids
Colitis, Ulcerative D003093 24 associated lipids
Stomach Ulcer D013276 75 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Nocardia Infections D009617 6 associated lipids
Diarrhea D003967 32 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Graft Occlusion, Vascular D006083 11 associated lipids
Hypercalcemia D006934 13 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with tacrolimus

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with tacrolimus?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with tacrolimus?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with tacrolimus?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with tacrolimus?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with tacrolimus?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with tacrolimus

Download all related citations
Per page 10 20 50 100 | Total 15051
Authors Title Published Journal PubMed Link
Peces R et al. Alloimmune haemolytic anaemia resulting from anti-A and anti-B antibody induced by group O graft in renal transplant recipients. 1998 Nephrol. Dial. Transplant. pmid:9681751
Medh RD et al. Agonist-specific modulation of glucocorticoid receptor-mediated transcription by immunosuppressants. 1998 Mol. Cell. Endocrinol. pmid:9685211
Tsuzuki S et al. FK506 (tacrolimus) inhibits extravasation of lymphoid cells by abrogating VLA-4/VCAM-1 mediated transendothelial migration. 1998 FEBS Lett. pmid:9688583
Kilmartin DJ et al. Tacrolimus (FK506) in failed cyclosporin A therapy in endogenous posterior uveitis. 1998 Ocul. Immunol. Inflamm. pmid:9689640
Ding JM et al. A neuronal ryanodine receptor mediates light-induced phase delays of the circadian clock. 1998 Nature pmid:9690474
Moriwaki A et al. An immunosuppressant, FK506, protects against neuronal dysfunction and death but has no effect on electrographic and behavioral activities induced by systemic kainate. 1998 Neuroscience pmid:9692722
Mihatsch MJ et al. The side-effects of ciclosporine-A and tacrolimus. 1998 Clin. Nephrol. pmid:9696431
Rejto PA and Verkhivker GM Molecular anchors with large stability gaps ensure linear binding free energy relationships for hydrophobic substituents. 1998 Pac Symp Biocomput pmid:9697196
[Tacrolimus in kidney transplantation. Bürgenstock, Switzerland, 20 March 1998]. 1998 Dtsch. Med. Wochenschr. pmid:9697633
Matsumoto T et al. Influence of FK506 on experimental atherosclerosis in cholesterol-fed rabbits. 1998 Atherosclerosis pmid:9699896
Duraj F et al. [Intestinal transplantation. The first Swedish transplantation of the small intestine in an adult patient with pseudoobstruction]. 1998 Lakartidningen pmid:9700261
Gruessner RW et al. Donor-specific portal blood transfusion in intestinal transplantation: a prospective, preclinical large animal study. 1998 Transplantation pmid:9701258
Garg UC et al. Comparison of the Abbott IMx Tacrolimus I and Tacrolimus II assays. 1998 Clin. Chem. pmid:9702984
Xu M et al. Effect of peritransplant FTY720 alone or in combination with post-transplant tacrolimus in a rat model of cardiac allotransplantation. 1998 Transpl. Int. pmid:9704394
Stone JH et al. Outcome of renal transplantation in ninety-seven cyclosporine-era patients with systemic lupus erythematosus and matched controls. 1998 Arthritis Rheum. pmid:9704643
Ogawa T et al. Osteoblastic differentiation is enhanced by rapamycin in rat osteoblast-like osteosarcoma (ROS 17/2.8) cells. 1998 Biochem. Biophys. Res. Commun. pmid:9705862
Khattab A et al. Cyclosporins: lack of correlation between antischistosomal properties and inhibition of cyclophilin isomerase activity. 1998 Exp. Parasitol. pmid:9709036
White MH et al. Randomized, double-blind clinical trial of amphotericin B colloidal dispersion vs. amphotericin B in the empirical treatment of fever and neutropenia. 1998 Clin. Infect. Dis. pmid:9709879
Ruetz S Yeast secretory vesicle system for expression and functional characterization of P-glycoproteins. 1998 Meth. Enzymol. pmid:9711569
Marsaud V et al. Dexamethasone and triamcinolone acetonide accumulation in mouse fibroblasts is differently modulated by the immunosuppressants cyclosporin A, FK506, rapamycin and their analogues, as well as by other P-glycoprotein ligands. 1998 J. Steroid Biochem. Mol. Biol. pmid:9712407