tacrolimus

Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.

Cross Reference

Introduction

To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with tacrolimus?

tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with tacrolimus

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Uremia D014511 33 associated lipids
Colitis, Ulcerative D003093 24 associated lipids
Stomach Ulcer D013276 75 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Nocardia Infections D009617 6 associated lipids
Diarrhea D003967 32 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Graft Occlusion, Vascular D006083 11 associated lipids
Hypercalcemia D006934 13 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with tacrolimus

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with tacrolimus?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with tacrolimus?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with tacrolimus?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with tacrolimus?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with tacrolimus?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with tacrolimus

Download all related citations
Per page 10 20 50 100 | Total 15051
Authors Title Published Journal PubMed Link
Moreno M et al. Monitoring of tacrolimus as rescue therapy in pediatric liver transplantation. 1998 Ther Drug Monit pmid:9712459
Holt DW and Johnston A Monitoring new immunosuppressive agents. Are the methods adequate? 1997 Drug Metabol Drug Interact pmid:9713574
Shaw LM Mycophenolate mofetil: pharmacokinetic strategies for optimizing immunosuppression. 1997 Drug Metabol Drug Interact pmid:9713576
Zini R et al. Tacrolimus decreases in vitro oxidative phosphorylation of mitochondria from rat forebrain. 1998 Life Sci. pmid:9714423
Iizuka K et al. InsP3, but not novel Ca2+ releasers, contributes to agonist-initiated contraction in rabbit airway smooth muscle. 1998 J. Physiol. (Lond.) pmid:9714870
Tamura F et al. FK506 promotes liver regeneration by suppressing natural killer cell activity. 1998 J. Gastroenterol. Hepatol. pmid:9715421
Fukuda K et al. cFKBP/SMAP; a novel molecule involved in the regulation of smooth muscle differentiation. 1998 Development pmid:9716519
Tao HR FK506 inhibits severe graft-versus-host disease without mediating the involvement of perforin and granzyme B. 1998 Hokkaido Igaku Zasshi pmid:9719949
Jacobson P et al. Tacrolimus: a new agent for the prevention of graft-versus-host disease in hematopoietic stem cell transplantation. 1998 Bone Marrow Transplant. pmid:9720734
Yang X et al. Essential role of CED-4 oligomerization in CED-3 activation and apoptosis. 1998 Science pmid:9721101
Srivastava M et al. Drug-associated acute-onset vanishing bile duct and Stevens-Johnson syndromes in a child. 1998 Gastroenterology pmid:9721172
Oellerich M et al. Therapeutic drug monitoring of cyclosporine and tacrolimus. Update on Lake Louise Consensus Conference on cyclosporin and tacrolimus. 1998 Clin. Biochem. pmid:9721427
Soldin SJ Role of immunophilins in therapeutic drug monitoring of immunosuppressive drugs. 1998 Clin. Biochem. pmid:9721438
Gruessner RW et al. Mycophenolate mofetil in pancreas transplantation. 1998 Transplantation pmid:9721799
Terakura M et al. Lymphoid/nonlymphoid compartmentalization of donor leukocyte chimerism in rat recipients of heart allografts, with or without adjunct bone marrow. 1998 Transplantation pmid:9721804
Glicklich D et al. Chronic renal allograft rejection: no response to mycophenolate mofetil. 1998 Transplantation pmid:9721811
Calandra S Sinus arrest during tacrolimus treatment: was the QT interval prolonged? 1998 Transplantation pmid:9721813
Kahan BD High variability of drug exposure: a biopharmaceutic risk factor for chronic rejection. 1998 Transplant. Proc. pmid:9723224
Keown PA and Primmett DR Cyclosporine: the principal immunosuppressant for renal transplantation. 1998 Transplant. Proc. pmid:9723252
Armenti VT et al. Pregnancy outcomes in female renal transplant recipients. 1998 Transplant. Proc. pmid:9723259