tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- Am. J. Physiol. Renal Physiol. (1)
- Drug Metab. Dispos. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| De Lemos-Bonotto M et al. | A systematic review and meta-analysis of second-line immunosuppressants for autoimmune hepatitis treatment. | 2018 | Eur J Gastroenterol Hepatol | pmid:29227329 |
| Mashiah J et al. | Topical pimecrolimus for paediatric cutaneous mastocytosis. | 2018 | Clin. Exp. Dermatol. | pmid:29460435 |
| Ng YZ et al. | Fluorescence Polarization Assay for Small Molecule Screening of FK506 Biosynthesized in 96-Well Microtiter Plates. | 2017 | Biochemistry | pmid:28841306 |
| Kita K and Mano Y | Application of volumetric absorptive microsampling device for quantification of tacrolimus in human blood as a model drug of high blood cell partition. | 2017 | J Pharm Biomed Anal | pmid:28601765 |
| Abongwa C et al. | Successful treatment of tacrolimus-related pure red cell aplasia and autoimmune hemolytic anemia with rituximab in a pediatric cardiac transplant patient. | 2017 | Pediatr Blood Cancer | pmid:28598573 |
| Wu Z et al. | FOXP3 rs3761548 polymorphism is associated with tacrolimus-induced acute nephrotoxicity in renal transplant patients. | 2017 | Eur. J. Clin. Pharmacol. | pmid:27747372 |
| Torres IB et al. | Tacrolimus and mycophenolate regimen and subclinical tubulo-interstitial inflammation in low immunological risk renal transplants. | 2017 | Transpl. Int. | pmid:28667664 |
| Ikebe T et al. | Hemophagocytic lymphohistiocytosis following influenza vaccination in a patient with aplastic anemia undergoing allogeneic bone marrow stem cell transplantation. | 2017 | Int. J. Hematol. | pmid:28054244 |
| Harada S et al. | Complete remission of angiolymphoid hyperplasia with eosinophilia using topical tacrolimus. | 2017 | Eur J Dermatol | pmid:28007668 |
| Zhang L et al. | Characterization of calcineurin from Cryptococcus humicola and the application of calcineurin in aluminum tolerance. | 2017 | BMC Biotechnol. | pmid:28356086 |
| Bellon H et al. | The Effect of Immunosuppression on Airway Integrity. | 2017 | Transplantation | pmid:28471870 |
| Cui W et al. | Therapy of tacrolimus combined with corticosteroids in idiopathic membranous nephropathy. | 2017 | Braz. J. Med. Biol. Res. | pmid:28355356 |
| Siponen M et al. | Topical tacrolimus, triamcinolone acetonide, and placebo in oral lichen planus: a pilot randomized controlled trial. | 2017 | Oral Dis | pmid:28168769 |
| Gao L et al. | Low incidence of acute graft-versus-host disease with short-term tacrolimus in haploidentical hematopoietic stem cell transplantation. | 2017 | Leuk. Res. | pmid:28273549 |
| Aschauer C et al. | Positioning of Tacrolimus for the Treatment of Diabetic Nephropathy Based on Computational Network Analysis. | 2017 | PLoS ONE | pmid:28060893 |
| de Oliveira JTP et al. | Variability index of tacrolimus serum levels in pediatric liver transplant recipients younger than 12Â years: Non-adherence or risk of non-adherence? | 2017 | Pediatr Transplant | pmid:29034612 |
| Kim YK et al. | New tablet formulation of tacrolimus with smaller interindividual variability may become a better treatment option than the conventional capsule formulation in organ transplant patients. | 2017 | Drug Des Devel Ther | pmid:29033547 |
| Tamura M et al. | [A case of anti-PL-7 antibody positive polymyositis with thrombotic microangiopathy]. | 2017 | Nihon Rinsho Meneki Gakkai Kaishi | pmid:29367529 |
| Perez LE et al. | Visilizumab with tacrolimus and methotrexate for GvHD prevention after allogeneic hematopoietic cell transplantation from mismatched unrelated donors. | 2017 | Bone Marrow Transplant. | pmid:27991896 |
| Qi H et al. | Integration of parallel C-labeling experiments and in silico pathway analysis for enhanced production of ascomycin. | 2017 | Biotechnol. Bioeng. | pmid:27869289 |