tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Vohra S et al. | Clinical and serological efficacy of topical calcineurin inhibitors in oral lichen planus: a prospective randomized controlled trial. | 2016 | Int. J. Dermatol. | pmid:26147635 |
| Herz S et al. | Checkpoint inhibitors in chronic kidney failure and an organ transplant recipient. | 2016 | Eur. J. Cancer | pmid:27614165 |
| Hazama Y et al. | Effect of Physiological Changes in the Skin on Systemic Absorption of Tacrolimus Following Topical Application in Rats. | 2016 | Biol. Pharm. Bull. | pmid:26934927 |
| Nakajima A et al. | Effectiveness of tacrolimus in comparison with methotrexate or biologics in propensity score-matched patients with rheumatoid arthritis. | 2016 | Mod Rheumatol | pmid:26934454 |
| Pan GH et al. | Low-dose tacrolimus combined with donor-derived mesenchymal stem cells after renal transplantation: a prospective, non-randomized study. | 2016 | Oncotarget | pmid:26933811 |
| Doke T et al. | Post-Transplant Membranous Nephropathy Associated with Chronic Active Antibody-Mediated Rejection and Hepatitis C Infection after Deceased Donor Renal Transplantation. | 2016 | Intern. Med. | pmid:26875963 |
| Knight SR | Intrapatient variability in tacrolimus exposure - a useful tool for clinical practice? | 2016 | Transpl. Int. | pmid:27283231 |
| Shuker N et al. | A high intrapatient variability in tacrolimus exposure is associated with poor long-term outcome of kidney transplantation. | 2016 | Transpl. Int. | pmid:27188932 |
| Rodrigues-Diez R et al. | Calcineurin inhibitors cyclosporine A and tacrolimus induce vascular inflammation and endothelial activation through TLR4 signaling. | 2016 | Sci Rep | pmid:27295076 |
| Wen X et al. | Comparison of Utilization and Clinical Outcomes for Belatacept- and Tacrolimus-Based Immunosuppression in Renal Transplant Recipients. | 2016 | Am. J. Transplant. | pmid:27137884 |
| Song JL et al. | Minimizing tacrolimus decreases the risk of new-onset diabetes mellitus after liver transplantation. | 2016 | World J. Gastroenterol. | pmid:26877618 |
| Viesselmann CW et al. | Clinically Significant Drug Interaction Between Clotrimazole and Tacrolimus in Pancreas Transplant Recipients and Associated Risk of Allograft Rejection. | 2016 | Pharmacotherapy | pmid:26877191 |
| Than NN et al. | Long-term follow-up of patients with difficult to treat type 1 autoimmune hepatitis on Tacrolimus therapy. | 2016 | Scand. J. Gastroenterol. | pmid:26458216 |
| Wang X et al. | Ureaplasma urealyticum Causes Hyperammonemia in an Experimental Immunocompromised Murine Model. | 2016 | PLoS ONE | pmid:27537683 |
| Malik N et al. | A simple office-based procedure for patients with extensive vitiligo. | 2016 | J. Am. Acad. Dermatol. | pmid:27745651 |
| Lee JH et al. | Stability of tacrolimus solutions in polyolefin containers. | 2016 | Am J Health Syst Pharm | pmid:26796907 |
| Cruzado JM et al. | Controlled randomized study comparing the cardiovascular profile of everolimus with tacrolimus in renal transplantation. | 2016 | Transpl. Int. | pmid:27648523 |
| Torrisi JS et al. | Inhibition of Inflammation and iNOS Improves Lymphatic Function in Obesity. | 2016 | Sci Rep | pmid:26796537 |
| Chatterjee S and Agrawal D | Tacrolimus in Corticosteroid-Refractory Vernal Keratoconjunctivitis. | 2016 | Cornea | pmid:27310883 |
| Ward I et al. | Digital Pulp Ulcerations and Inverse Gottron Papules in Melanoma Differentiation-Associated Gene 5-Related Dermatomyositis. | 2016 | J Clin Rheumatol | pmid:27464773 |
| EriÅŸ E et al. | Evaluation of Effect of Topical Tacrolimus Treatment on Herpetic Stromal Keratitis in a Rat Model. | 2016 | Eye Contact Lens | pmid:25996419 |
| Armand P et al. | The addition of sirolimus to the graft-versus-host disease prophylaxis regimen in reduced intensity allogeneic stem cell transplantation for lymphoma: a multicentre randomized trial. | 2016 | Br. J. Haematol. | pmid:26729448 |
| Lee B et al. | Appropriate timing of tacrolimus concentration measurements in the emergency department. | 2016 | Am J Health Syst Pharm | pmid:27543574 |
| Komaki Y et al. | Efficacy and Safety of Tacrolimus Therapy for Active Ulcerative Colitis; A Systematic Review and Meta-analysis. | 2016 | J Crohns Colitis | pmid:26645641 |
| Vadcharavivad S et al. | Population pharmacokinetics of tacrolimus in Thai kidney transplant patients: comparison with similar data from other populations. | 2016 | J Clin Pharm Ther | pmid:27191538 |
| Thevissen K | How promising are combinatorial drug strategies in combating Candida albicans biofilms? | 2016 | Future Med Chem | pmid:27463947 |
| Ikeya K et al. | The Ulcerative Colitis Endoscopic Index of Severity More Accurately Reflects Clinical Outcomes and Long-term Prognosis than the Mayo Endoscopic Score. | 2016 | J Crohns Colitis | pmid:26581895 |
| Gala-Lopez BL et al. | Antiaging Glycopeptide Protects Human Islets Against Tacrolimus-Related Injury and Facilitates Engraftment in Mice. | 2016 | Diabetes | pmid:26581595 |
| Milgrom SA et al. | Graft-versus-host disease after radiation therapy in patients who have undergone allogeneic stem cell transplantation: two case reports. | 2016 | J Med Case Rep | pmid:27465468 |
| Cena T et al. | De novo noncutaneous malignancies after kidney transplantation are associated with an increased risk of graft failure: results from a time-dependent analysis on 672 patients. | 2016 | Transpl. Int. | pmid:27343849 |
| Moes DJ et al. | Population pharmacokinetics and pharmacogenetics of once daily tacrolimus formulation in stable liver transplant recipients. | 2016 | Eur. J. Clin. Pharmacol. | pmid:26521259 |
| Yeo L and Ormerod AD | Oral tacrolimus: a treatment option for recalcitrant erosive lichen planus. | 2016 | Clin. Exp. Dermatol. | pmid:27339859 |
| Gardiner KM et al. | Multinational Evaluation of Mycophenolic Acid, Tacrolimus, Cyclosporin, Sirolimus, and Everolimus Utilization. | 2016 | Ann. Transplant. | pmid:26729299 |
| Chacon A and Mercer J | Successful management of angiolymphoid hyperplasia with eosinophilia in a split-face trial of topical tacrolimus and timolol solution. | 2016 | G Ital Dermatol Venereol | pmid:25014586 |
| Grześk E et al. | Cyclosporine-A, but not tacrolimus significantly increases reactivity of vascular smooth muscle cells. | 2016 | Pharmacol Rep | pmid:26721374 |
| Riegersperger M et al. | The Effect of ABCB1 Polymorphisms on Serial Tacrolimus Concentrations in Stable Austrian Long-Term Kidney Transplant Recipients. | 2016 | Clin. Lab. | pmid:28164520 |
| Levitsky J et al. | Immunoregulatory Effects of Everolimus on In Vitro Alloimmune Responses. | 2016 | PLoS ONE | pmid:27275747 |
| Schneider L et al. | Study of the Atopic March: Development of Atopic Comorbidities. | 2016 | Pediatr Dermatol | pmid:27273433 |
| Kostereva NV et al. | IGF-1 and Chondroitinase ABC Augment Nerve Regeneration after Vascularized Composite Limb Allotransplantation. | 2016 | PLoS ONE | pmid:27272754 |
| Sisti A et al. | Effectiveness and safety of topical tacrolimus monotherapy for repigmentation in vitiligo: a comprehensive literature review. | 2016 | An Bras Dermatol | pmid:27192518 |
| Ramachandran R et al. | Cyclical cyclophosphamide and steroids is effective in resistant or relapsing nephrotic syndrome due to M-type phospholipase A2 receptor-related membranous nephropathy after tacrolimus therapy. | 2016 | Kidney Int. | pmid:27181781 |
| Bican Demir A et al. | Two Cases With Developing Neurologic Complications After Liver Transplant. | 2016 | Exp Clin Transplant | pmid:26643318 |
| Baraldo M | Meltdose Tacrolimus Pharmacokinetics. | 2016 | Transplant. Proc. | pmid:27109969 |
| Pretagostini R et al. | Delayed Introduction of Everolimus in De Novo Renal Transplanted Patients: A Single-Center Experience. | 2016 | Transplant. Proc. | pmid:27109947 |
| Park OJ et al. | A combination of excimer laser treatment and topical tacrolimus is more effective in treating vitiligo than either therapy alone for the initial 6 months, but not thereafter. | 2016 | Clin. Exp. Dermatol. | pmid:26299799 |
| Felix MJ et al. | Time-Dependent and Immunosuppressive Drug-Associated Adverse Event Profiles in De Novo Kidney Transplant Recipients Converted from Tacrolimus to Sirolimus Regimens. | 2016 | Pharmacotherapy | pmid:26799522 |
| Vanhove T et al. | High Intrapatient Variability of Tacrolimus Concentrations Predicts Accelerated Progression of Chronic Histologic Lesions in Renal Recipients. | 2016 | Am. J. Transplant. | pmid:27013142 |
| Kanazawa H et al. | Chemotherapy-induced B-cell depletion in hepatoblastoma patients undergoing ABO-incompatible living donor liver transplantation. | 2016 | Pediatr Transplant | pmid:27012966 |
| Ha DH et al. | Potential differentiation ability of gingiva originated human mesenchymal stem cell in the presence of tacrolimus. | 2016 | Sci Rep | pmid:27721434 |
| Taşoğlu Ö et al. | Pregabalin: A New Adjunct in Calcineurin Inhibitor Pain Syndrome Treatment. | 2016 | Prog Transplant | pmid:27312682 |