tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- J. Pharmacol. Exp. Ther. (1)
- Am. J. Physiol. Renal Physiol. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Yamada H et al. | Simvastatin-tacrolimus and simvastatin-cyclosporin interactions in rats. | 1998 | Biopharm Drug Dispos | pmid:9673778 |
| Trindade E et al. | Use of granulocyte macrophage colony stimulating factor in children after orthotopic liver transplantation. | 1998 | J. Hepatol. | pmid:9672183 |
| Polak J et al. | Primary pulmonary hypertension: pathologist as patient. | 1998 May-Jun | J R Coll Physicians Lond | pmid:9670148 |
| Gross A et al. | Enforced dimerization of BAX results in its translocation, mitochondrial dysfunction and apoptosis. | 1998 | EMBO J. | pmid:9670005 |
| Takamatsu Y et al. | IL-13 production by peripheral blood mononuclear cells from patients with atopic dermatitis. | 1998 | Dermatology (Basel) | pmid:9669111 |
| Horigome A et al. | Tacrolimus-induced apoptosis and its prevention by interleukins in mitogen-activated human peripheral-blood mononuclear cells. | 1998 | Immunopharmacology | pmid:9667420 |
| Romero E et al. | [Tacrolimus and hypertrophic cardiomyopathy]. | 1998 | Med Clin (Barc) | pmid:9666425 |
| Morris-Stiff G et al. | Prospective randomised study comparing tacrolimus (Prograf) and cyclosporin (Neoral) as primary immunosuppression in cadaveric renal transplants at a single institution: interim report of the first 80 cases. | 1998 | Transpl. Int. | pmid:9665010 |
| Peter C et al. | Does tacrolimus cause more severe anemia than cyclosporine A in children after renal transplantation? | 1998 | Transpl. Int. | pmid:9665008 |
| Zhang JG et al. | Differential effects of cyclosporin A and tacrolimus on the production of TGF-beta: implications for the development of obliterative bronchiolitis after lung transplantation. | 1998 | Transpl. Int. | pmid:9665007 |
| Charco R et al. | Early use of tacrolimus as rescue therapy for refractory liver allograft rejection. | 1998 | Transpl. Int. | pmid:9665004 |
| Horimoto H et al. | Transplantation tolerance by a combined therapy with sulfatide, anti-LFA-1/ICAM-1 monoclonal antibodies and FK506 in rat cardiac transplantation. | 1998 | Transpl. Int. | pmid:9665003 |
| Jara P et al. | Tacrolimus for steroid-resistant liver rejection in children. | 1998 | Transpl. Int. | pmid:9664996 |
| Reggiani P et al. | Rescue FK506 early conversion for refractory rejection after pediatric liver transplantation: experience in 20 children. | 1998 | Transpl. Int. | pmid:9664995 |
| Pou L et al. | Influence of posttransplant time on dose and concentration of tacrolimus in liver transplant patients. | 1998 | Transpl. Int. | pmid:9664994 |
| Margarit C et al. | Efficacy and safety of oral low-dose tacrolimus treatment in liver transplantation. | 1998 | Transpl. Int. | pmid:9664992 |
| Hernández-Herrera G et al. | Tacrolimus rescue therapy for cyclosporine-induced nephrotoxicity. | 1998 | Transpl. Int. | pmid:9664956 |
| Kyo M et al. | Morphological findings in non-episode biopsies of kidney transplant allografts treated with FK506 or cyclosporine. | 1998 | Transpl. Int. | pmid:9664955 |
| Morris-Stiff G et al. | Conversion of renal transplant recipients from cyclosporin (neoral) to tacrolimus (prograf) for haemolytic uraemic syndrome. | 1998 | Transpl. Int. | pmid:9664954 |
| Morris-Stiff G et al. | Conversion of renal transplant recipients from cyclosporin to low-dose tacrolimus for refractory rejection. | 1998 | Transpl. Int. | pmid:9664949 |
| Hauser IA and Neumayer HN | Tacrolimus and cyclosporine efficacy in high-risk kidney transplantation. European Multicentre Tacrolimus (FK506) Renal Study Group. | 1998 | Transpl. Int. | pmid:9664948 |
| Kokado Y et al. | Low-dose tacrolimus (FK506)-based immunosuppressive protocol in living donor renal transplantation. | 1998 | Transpl. Int. | pmid:9664945 |
| Stockwell BR and Schreiber SL | TGF-beta-signaling with small molecule FKBP12 antagonists that bind myristoylated FKBP12-TGF-beta type I receptor fusion proteins. | 1998 | Chem. Biol. | pmid:9662508 |
| Nagayasu T et al. | Expression of proliferating cell nuclear antigen in bronchial epithelium after lung transplantation in the rat. | 1998 | J. Heart Lung Transplant. | pmid:9662091 |
| Lai MM et al. | Cain, a novel physiologic protein inhibitor of calcineurin. | 1998 | J. Biol. Chem. | pmid:9660798 |
| Tsujikawa A et al. | Tacrolimus (FK506) attenuates leukocyte accumulation after transient retinal ischemia. | 1998 | Stroke | pmid:9660400 |
| Bader G et al. | Reduction of cyclosporine-induced gingival overgrowth following a change to tacrolimus. A case history involving a liver transplant patient. | 1998 | J. Periodontol. | pmid:9660343 |
| McBride WJ et al. | Allogeneic fetal intestinal transplantation with FK506 immunosuppression. | 1998 | J. Pediatr. Surg. | pmid:9660232 |
| Fujino T et al. | The immunosuppressive compound FK506 does not affect expulsion of Echinostoma trivolvis in C3H mice. | 1998 | Parasitol. Res. | pmid:9660146 |
| Le Bihan S et al. | Calcium/calmodulin kinase inhibitors and immunosuppressant macrolides rapamycin and FK506 inhibit progestin- and glucocorticosteroid receptor-mediated transcription in human breast cancer T47D cells. | 1998 | Mol. Endocrinol. | pmid:9658403 |
| Sasa H et al. | Hepatic extraction of tacrolimus in rats with experimental liver diseases. | 1998 | Biol. Pharm. Bull. | pmid:9657047 |
| Nishioka T et al. | [Is tacrolimus effective for ongoing renal allograft rejection?]. | 1998 | Hinyokika Kiyo | pmid:9656112 |
| Morozumi K et al. | [Current topics of the rejection pathology in human renal allografts]. | 1998 | Hinyokika Kiyo | pmid:9656109 |
| Tamura K | [Multiple actions of tacrolimus and cyclosporin A as specific inhibitors of calcineurin]. | 1998 | Tanpakushitsu Kakusan Koso | pmid:9655970 |
| Matsui H et al. | [Physiological role of calcineurin in central nervous system]. | 1998 | Tanpakushitsu Kakusan Koso | pmid:9655961 |
| Cetinkale O et al. | Involvement of neutrophils in ischemia-reperfusion injury of inguinal island skin flaps in rats. | 1998 | Plast. Reconstr. Surg. | pmid:9655420 |
| Kommers T et al. | Regulation of the phosphorylation of glial fibrillary acidic protein (GFAP) by glutamate and calcium ions in slices of immature rat spinal cord: comparison with immature hippocampus. | 1998 | Neurosci. Lett. | pmid:9654363 |
| Tarumi K et al. | The plasma FK506-binding protein 12 level is related to acute cellular rejection in small bowel transplantation. | 1998 | Immunopharmacol Immunotoxicol | pmid:9653668 |
| Friberg H et al. | Cyclosporin A, but not FK 506, protects mitochondria and neurons against hypoglycemic damage and implicates the mitochondrial permeability transition in cell death. | 1998 | J. Neurosci. | pmid:9651198 |
| Canzanello VJ et al. | Late hypertension after liver transplantation: a comparison of cyclosporine and tacrolimus (FK 506). | 1998 | Liver Transpl Surg | pmid:9649648 |
| Gabe SM et al. | The effect of tacrolimus (FK506) on intestinal barrier function and cellular energy production in humans. | 1998 | Gastroenterology | pmid:9649460 |
| Gruessner RW et al. | Suggested guidelines for the use of tacrolimus in pancreas/kidney transplantation. | 1998 | Clin Transplant | pmid:9642520 |
| Kuwata T et al. | A role of calcineurin in coreceptor regulation during differentiation of Cd4+Cd8+ T cells. | 1998 | Biochem. Biophys. Res. Commun. | pmid:9642110 |
| Murray M et al. | Comparison of tacrolimus absorption in transplant patients receiving continuous versus interrupted enteral nutritional feeding. | 1998 | Ann Pharmacother | pmid:9640479 |
| Morris-Stiff G and Jurewicz WA | Single centre experience with mycophenolate mofetil for refractory rejection in cadaveric renal transplantation. | 1998 | Transpl. Int. | pmid:9638849 |
| Takahara S et al. | A comparative study of FK506 granules and capsules in renal transplant recipients. | 1998 | Transpl. Int. | pmid:9638846 |
| Abraham RT | Mammalian target of rapamycin: immunosuppressive drugs uncover a novel pathway of cytokine receptor signaling. | 1998 | Curr. Opin. Immunol. | pmid:9638370 |
| Baldari CT et al. | NF-AT-luciferase reporter T cell lines as tools to screen immunosuppressive drugs. | 1998 | Biologicals | pmid:9637743 |
| Resch K and Szamel M | Molecular mechanisms of the immunosuppressive action of cyclosporin A. | 1997 Sep-Oct | Int. J. Immunopharmacol. | pmid:9637358 |
| Schneeberger H et al. | Tacrolimus as a primary immunosuppressive therapy in cadaveric renal transplantation: five years' experience at a single center. | 1998 | Transplant. Proc. | pmid:9636642 |