Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with tacrolimus
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Yamada H et al. | Simvastatin-tacrolimus and simvastatin-cyclosporin interactions in rats. | 1998 | Biopharm Drug Dispos | pmid:9673778 |
Trindade E et al. | Use of granulocyte macrophage colony stimulating factor in children after orthotopic liver transplantation. | 1998 | J. Hepatol. | pmid:9672183 |
Polak J et al. | Primary pulmonary hypertension: pathologist as patient. | 1998 May-Jun | J R Coll Physicians Lond | pmid:9670148 |
Gross A et al. | Enforced dimerization of BAX results in its translocation, mitochondrial dysfunction and apoptosis. | 1998 | EMBO J. | pmid:9670005 |
Takamatsu Y et al. | IL-13 production by peripheral blood mononuclear cells from patients with atopic dermatitis. | 1998 | Dermatology (Basel) | pmid:9669111 |
Horigome A et al. | Tacrolimus-induced apoptosis and its prevention by interleukins in mitogen-activated human peripheral-blood mononuclear cells. | 1998 | Immunopharmacology | pmid:9667420 |
Romero E et al. | [Tacrolimus and hypertrophic cardiomyopathy]. | 1998 | Med Clin (Barc) | pmid:9666425 |
Morris-Stiff G et al. | Prospective randomised study comparing tacrolimus (Prograf) and cyclosporin (Neoral) as primary immunosuppression in cadaveric renal transplants at a single institution: interim report of the first 80 cases. | 1998 | Transpl. Int. | pmid:9665010 |
Peter C et al. | Does tacrolimus cause more severe anemia than cyclosporine A in children after renal transplantation? | 1998 | Transpl. Int. | pmid:9665008 |
Zhang JG et al. | Differential effects of cyclosporin A and tacrolimus on the production of TGF-beta: implications for the development of obliterative bronchiolitis after lung transplantation. | 1998 | Transpl. Int. | pmid:9665007 |
Charco R et al. | Early use of tacrolimus as rescue therapy for refractory liver allograft rejection. | 1998 | Transpl. Int. | pmid:9665004 |
Horimoto H et al. | Transplantation tolerance by a combined therapy with sulfatide, anti-LFA-1/ICAM-1 monoclonal antibodies and FK506 in rat cardiac transplantation. | 1998 | Transpl. Int. | pmid:9665003 |
Jara P et al. | Tacrolimus for steroid-resistant liver rejection in children. | 1998 | Transpl. Int. | pmid:9664996 |
Reggiani P et al. | Rescue FK506 early conversion for refractory rejection after pediatric liver transplantation: experience in 20 children. | 1998 | Transpl. Int. | pmid:9664995 |
Pou L et al. | Influence of posttransplant time on dose and concentration of tacrolimus in liver transplant patients. | 1998 | Transpl. Int. | pmid:9664994 |
Margarit C et al. | Efficacy and safety of oral low-dose tacrolimus treatment in liver transplantation. | 1998 | Transpl. Int. | pmid:9664992 |
Hernández-Herrera G et al. | Tacrolimus rescue therapy for cyclosporine-induced nephrotoxicity. | 1998 | Transpl. Int. | pmid:9664956 |
Kyo M et al. | Morphological findings in non-episode biopsies of kidney transplant allografts treated with FK506 or cyclosporine. | 1998 | Transpl. Int. | pmid:9664955 |
Morris-Stiff G et al. | Conversion of renal transplant recipients from cyclosporin (neoral) to tacrolimus (prograf) for haemolytic uraemic syndrome. | 1998 | Transpl. Int. | pmid:9664954 |
Morris-Stiff G et al. | Conversion of renal transplant recipients from cyclosporin to low-dose tacrolimus for refractory rejection. | 1998 | Transpl. Int. | pmid:9664949 |