tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- J. Pharmacol. Exp. Ther. (1)
- Am. J. Physiol. Renal Physiol. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Mercuri A et al. | In vitro and in silico characterisation of Tacrolimus released under biorelevant conditions. | 2016 | Int J Pharm | pmid:27737809 |
| Ochi H et al. | Notalgia paresthetica: treatment with topical tacrolimus. | 2016 | J Eur Acad Dermatol Venereol | pmid:25388817 |
| Jain A et al. | Tacrolimus and curcumin co-loaded liposphere gel: Synergistic combination towards management of psoriasis. | 2016 | J Control Release | pmid:27725194 |
| Chen YF et al. | Tacrolimus inhibits vasoconstriction by increasing Ca(2+) sparks in rat aorta. | 2016 | J. Huazhong Univ. Sci. Technol. Med. Sci. | pmid:26838733 |
| Pathak S et al. | Preparation of High-Payload, Prolonged-Release Biodegradable Poly(lactic-co-glycolic acid)-Based Tacrolimus Microspheres Using the Single-Jet Electrospray Method. | 2016 | Chem. Pharm. Bull. | pmid:26833445 |
| Jannot AS et al. | A Lack of Significant Effect of POR*28 Allelic Variant on Tacrolimus Exposure in Kidney Transplant Recipients. | 2016 | Ther Drug Monit | pmid:26829596 |
| Dayal S et al. | Treatment of Childhood Vitiligo Using Tacrolimus Ointment with Narrowband Ultraviolet B Phototherapy. | 2016 | Pediatr Dermatol | pmid:27699846 |
| Borges-Costa J et al. | Kaposi's sarcoma presenting as violaceous macules on the chest of a kidney transplanted patient. | 2016 | BMJ Case Rep | pmid:26759393 |
| Vanhove T et al. | Clinical determinants of calcineurin inhibitor disposition: a mechanistic review. | 2016 | Drug Metab. Rev. | pmid:26912097 |
| Tamhankar MA et al. | Tacrolimus-induced cerebral blindness in a liver transplant patient. | 2016 | Indian J Ophthalmol | pmid:23619482 |
| Tsipotis E et al. | Bioavailability, Efficacy and Safety of Generic Immunosuppressive Drugs for Kidney Transplantation: A Systematic Review and Meta-Analysis. | 2016 | Am. J. Nephrol. | pmid:27576318 |
| Kravljaca M et al. | The importance of MDR1 gene polymorphisms for tacrolimus dosage. | 2016 | Eur J Pharm Sci | pmid:26705892 |
| Wang J et al. | Evaluation of mycophenolate mofetil or tacrolimus in children with steroid sensitive but frequently relapsing or steroid-dependent nephrotic syndrome. | 2016 | Nephrology (Carlton) | pmid:26697959 |
| Åžavk E | Neurologic Itch Management. | 2016 | Curr. Probl. Dermatol. | pmid:27578080 |
| Early CR et al. | Effect of metronidazole use on tacrolimus concentrations in transplant patients treated for Clostridium difficile. | 2016 | Transpl Infect Dis | pmid:27501504 |
| Okuda K et al. | Targeted Therapy for Acute Autoimmune Myocarditis with Nano-Sized Liposomal FK506 in Rats. | 2016 | PLoS ONE | pmid:27501378 |
| Delli K et al. | Comment on: 'Efficacy of topical tacrolimus for oral lichen planus: real-life experience in a retrospective cohort of patients with a review of the literature' by Ribero et al. (2015). | 2016 | J Eur Acad Dermatol Venereol | pmid:26616360 |
| Niioka T et al. | Influence of everolimus on the pharmacokinetics of tacrolimus in Japanese renal transplant patients. | 2016 | Int. J. Urol. | pmid:26990259 |
| Chen Y et al. | Clinicopathological features and prognosis of Kimura's disease with renal involvement in Chinese patients. | 2016 | Clin. Nephrol. | pmid:27142199 |
| Hermans C et al. | Atypical discrete papular lichen myxedematosus associated with monoclonal gammopathy: report of four cases and review of the literature. | 2016 | J Eur Acad Dermatol Venereol | pmid:27422288 |
| Zhang Y et al. | Effect of FK506 on apoptosis of facial motor neurons in rats and its possible mechanism. | 2016 | Eur Arch Otorhinolaryngol | pmid:25784181 |
| Ibrahim MA et al. | Study of intercurrent infection pattern in hepatitis C seropositive renal transplant recipients, relationship with T-cell function. | 2016 | Ren Fail | pmid:27418152 |
| Bessa AB et al. | Prospective Randomized Trial Investigating the Influence of Pharmaceutical Care on the Intra-Individual Variability of Tacrolimus Concentrations Early After Kidney Transplant. | 2016 | Ther Drug Monit | pmid:27414973 |
| MacDonald C et al. | Acute kidney injury after heart transplant in young children: risk factors and outcomes. | 2016 | Pediatr. Nephrol. | pmid:26559064 |
| Pastor-Clerigues A et al. | Evaluation of the Ocular Tolerance of Three Tacrolimus Topical Pharmaceutical Preparations by Bovine Corneal Opacity and Permeability Test. | 2016 | Curr. Eye Res. | pmid:26554729 |
| Vanhove T et al. | Comparative performance of oral midazolam clearance and plasma 4β-hydroxycholesterol to explain interindividual variability in tacrolimus clearance. | 2016 | Br J Clin Pharmacol | pmid:27501475 |
| Stiehl SR et al. | Tacrolimus interaction with dexmedetomidine--a case report. | 2016 | Pediatr Transplant | pmid:26493547 |
| Kato H et al. | Long-Term Influence of CYP3A5 Gene Polymorphism on Pharmacokinetics of Tacrolimus and Patient Outcome After Living Donor Liver Transplantation. | 2016 | Transplant. Proc. | pmid:27320564 |
| Kang SW et al. | Inhibition of senescence and promotion of the proliferation of chondrocytes from articular cartilage by CsA and FK506 involves inhibition of p38MAPK. | 2016 | Mech. Ageing Dev. | pmid:26704447 |
| Yoshimura N et al. | Effectiveness of the Combination of Everolimus and Tacrolimus With High Dosage of Mizoribine for Living Donor-Related Kidney Transplantation. | 2016 | Transplant. Proc. | pmid:27234736 |
| Yamanaka K et al. | Induction Immunosuppressive Therapy With Everolimus and Low-Dose Tacrolimus Extended-Release Preserves Good Renal Function at 1Â Year After Kidney Transplantation. | 2016 | Transplant. Proc. | pmid:27234735 |
| Lazelle RA et al. | Renal Deletion of 12 kDa FK506-Binding Protein Attenuates Tacrolimus-Induced Hypertension. | 2016 | J. Am. Soc. Nephrol. | pmid:26432904 |
| Hannah J et al. | Tacrolimus use in lupus nephritis: A systematic review and meta-analysis. | 2016 | Autoimmun Rev | pmid:26427983 |
| Prytuła AA et al. | The Effect of Weight and CYP3A5 Genotype on the Population Pharmacokinetics of Tacrolimus in Stable Paediatric Renal Transplant Recipients. | 2016 | Clin Pharmacokinet | pmid:27138785 |
| Yamamoto T et al. | Letter: which patient profile for tacrolimus in ulcerative colitis? Authors' reply. | 2016 | Aliment. Pharmacol. Ther. | pmid:27137731 |
| Kim MJ et al. | Effect of Immunosuppressive Drugs on the Changes of Serum Galactose-Deficient IgA1 in Patients with IgA Nephropathy. | 2016 | PLoS ONE | pmid:27930655 |
| Wei Q et al. | Efficacy and Safety of a Steroid-Free Immunosuppressive Regimen after Liver Transplantation for Hepatocellular Carcinoma. | 2016 | Gut Liver | pmid:27074818 |
| Shin J et al. | Prolyl hydroxylase domain 2 deficiency promotes skeletal muscle fiber-type transition via a calcineurin/NFATc1-dependent pathway. | 2016 | Skelet Muscle | pmid:26949511 |
| Gambarino S et al. | Human Cytomegalovirus Impact on mir-146a Expression Levels in Kidney Transplant Patients. | 2016 | Viral Immunol. | pmid:27077822 |
| Saeki H et al. | Clinical Practice Guidelines for the Management of Atopic Dermatitis 2016. | 2016 | J. Dermatol. | pmid:27076388 |
| Ueda Y and Uemoto S | Decreased tacrolimus concentration following a temporal increase during interferon-free therapy with asunaprevir and daclatasvir in patients with recurrent hepatitis C after liver transplantation. | 2016 | Transpl. Int. | pmid:26270021 |
| Mettang T | Uremic Itch Management. | 2016 | Curr. Probl. Dermatol. | pmid:27578082 |
| Mok CC et al. | Tacrolimus versus mycophenolate mofetil for induction therapy of lupus nephritis: a randomised controlled trial and long-term follow-up. | 2016 | Ann. Rheum. Dis. | pmid:25550339 |
| Xie L et al. | Pretransplantation Risk Factors Associated With New-onset Diabetes After Living-donor Kidney Transplantation. | 2016 | Transplant. Proc. | pmid:27931572 |
| Hitzeman N and Kinnevey C | Topical Tacrolimus for Eczema. | 2016 | Am Fam Physician | pmid:27929217 |
| Awdishu L and Joy MS | Role of Pharmacogenomics in Kidney Disease and Injury. | 2016 | Adv Chronic Kidney Dis | pmid:26979149 |
| Song GW et al. | A Pilot Study of the Pharmacokinetics of the Modified-Release Once-Daily Tacrolimus Formulation Administered to Living-Donor Liver Transplant Recipients. | 2016 | Exp Clin Transplant | pmid:26976646 |
| Saadi A and Schmahmann JD | Pearls & Oy-sters: Tacrolimus neurotoxicity presenting as an isolated brainstem lesion. | 2016 | Neurology | pmid:26976521 |
| Fix OK et al. | Liver transplant alone without kidney transplant for fibrinogen Aα-chain (AFib) renal amyloidosis. | 2016 | Amyloid | pmid:26972447 |
| Stockwell J et al. | Protein phosphatase role in adenosine A1 receptor-induced AMPA receptor trafficking and rat hippocampal neuronal damage in hypoxia/reperfusion injury. | 2016 | Neuropharmacology | pmid:26626486 |