Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with tacrolimus
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Ohye H et al. | Effects of immunosuppressant agents on growth hormone release and gene expression. | 1998 | Endocr. J. | pmid:9790238 |
Bajaj-Elliott M et al. | Interactions between stromal cell--derived keratinocyte growth factor and epithelial transforming growth factor in immune-mediated crypt cell hyperplasia. | 1998 | J. Clin. Invest. | pmid:9788959 |
Masugi T and Otsuka K | [Immunosuppressive drugs and calcineurin]. | 1998 | Tanpakushitsu Kakusan Koso | pmid:9788176 |
Heering P et al. | Distal tubular acidosis induced by FK506. | 1998 | Clin Transplant | pmid:9787958 |
Wu A et al. | Outcome of 22 successful pregnancies after liver transplantation. | 1998 | Clin Transplant | pmid:9787957 |
Peddi VR et al. | Use of tacrolimus eliminates acute rejection as a major complication following simultaneous kidney and pancreas transplantation. | 1998 | Clin Transplant | pmid:9787948 |
Rayes N et al. | Pregnancies following liver transplantation--how safe are they? A report of 19 cases under cyclosporine A and tacrolimus. | 1998 | Clin Transplant | pmid:9787947 |
Nishida T et al. | [FK506 for the prophylaxis of graft-versus-host-disease after bone marrow transplantation from HLA-genotypically mismatched unrelated donor]. | 1998 | Rinsho Ketsueki | pmid:9785975 |
Maestri M et al. | [Treatment of the nephrotoxicity of immunosuppressive drugs with insulin-like growth factor-I]. | 1998 | Minerva Chir | pmid:9780630 |
Motamedi H and Shafiee A | The biosynthetic gene cluster for the macrolactone ring of the immunosuppressant FK506. | 1998 | Eur. J. Biochem. | pmid:9780228 |