Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with tacrolimus
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Karanam BV et al. | Disposition of L-732,531, a potent immunosuppressant, in rats and baboons. | 1998 | Drug Metab. Dispos. | pmid:9763399 |
Zonneveld IM et al. | Topical tacrolimus is not effective in chronic plaque psoriasis. A pilot study. | 1998 | Arch Dermatol | pmid:9762021 |
Ohye H et al. | Cellular signaling mechanisms for stimulation of growth hormone secretion and growth hormone primary transcripts by immunosuppressant agents, FK506 and cyclosporin A, in cultured rat pituitary cells. | 1998 Nov-Dec | Neuroimmunomodulation | pmid:9762012 |
Kliem V and Brunkhorst R | Tacrolimus in kidney transplantation. | 1998 | Contrib Nephrol | pmid:9761977 |
Schambeck CM et al. | Limit of quantification (functional sensitivity) of the new IMx Tacrolimus II microparticle enzyme immunoassay. | 1998 | Clin. Chem. | pmid:9761266 |
Ishizuka T et al. | Stem cell factor augments Fc epsilon RI-mediated TNF-alpha production and stimulates MAP kinases via a different pathway in MC/9 mast cells. | 1998 | J. Immunol. | pmid:9759885 |
Teshima R et al. | Ca2+-ATPase inhibitors and PKC activation synergistically stimulate TNF-alpha production in RBL-2H3 cells. | 1998 | Inflamm. Res. | pmid:9754866 |
Xu Q et al. | Molecular characterization of a plant FKBP12 that does not mediate action of FK506 and rapamycin. | 1998 | Plant J. | pmid:9753776 |
Radkowski M et al. | Detection of hepatitis C virus replication in peripheral blood mononuclear cells after orthotopic liver transplantation. | 1998 | Transplantation | pmid:9753352 |
Woodle ES et al. | Liver transplantation in the first three months of life. | 1998 | Transplantation | pmid:9753340 |