Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with tacrolimus
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Srivastava M et al. | Drug-associated acute-onset vanishing bile duct and Stevens-Johnson syndromes in a child. | 1998 | Gastroenterology | pmid:9721172 |
Yang X et al. | Essential role of CED-4 oligomerization in CED-3 activation and apoptosis. | 1998 | Science | pmid:9721101 |
Jacobson P et al. | Tacrolimus: a new agent for the prevention of graft-versus-host disease in hematopoietic stem cell transplantation. | 1998 | Bone Marrow Transplant. | pmid:9720734 |
Tao HR | FK506 inhibits severe graft-versus-host disease without mediating the involvement of perforin and granzyme B. | 1998 | Hokkaido Igaku Zasshi | pmid:9719949 |
Fukuda K et al. | cFKBP/SMAP; a novel molecule involved in the regulation of smooth muscle differentiation. | 1998 | Development | pmid:9716519 |
Tamura F et al. | FK506 promotes liver regeneration by suppressing natural killer cell activity. | 1998 | J. Gastroenterol. Hepatol. | pmid:9715421 |
Iizuka K et al. | InsP3, but not novel Ca2+ releasers, contributes to agonist-initiated contraction in rabbit airway smooth muscle. | 1998 | J. Physiol. (Lond.) | pmid:9714870 |
Zini R et al. | Tacrolimus decreases in vitro oxidative phosphorylation of mitochondria from rat forebrain. | 1998 | Life Sci. | pmid:9714423 |
Shaw LM | Mycophenolate mofetil: pharmacokinetic strategies for optimizing immunosuppression. | 1997 | Drug Metabol Drug Interact | pmid:9713576 |
Holt DW and Johnston A | Monitoring new immunosuppressive agents. Are the methods adequate? | 1997 | Drug Metabol Drug Interact | pmid:9713574 |