Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with tacrolimus
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Birdwell KA et al. | Decreased antibody response to influenza vaccination in kidney transplant recipients: a prospective cohort study. | 2009 | Am. J. Kidney Dis. | pmid:19185404 |
Lien YH and Bracamonte ER | Quiz page February 2011: acute kidney injury, graft pain, and subtherapeutic levels of tacrolimus. | 2011 | Am. J. Kidney Dis. | pmid:21251536 |
Pavan M et al. | Altered bioavailability of tacrolimus following intravenous administration of tigecycline. | 2011 | Am. J. Kidney Dis. | pmid:21251548 |
Vischini G et al. | Increased plasma levels of tacrolimus after ingestion of green tea. | 2011 | Am. J. Kidney Dis. | pmid:21787983 |
van Duijnhoven EM et al. | A late episode of post-transplant diabetes mellitus during active hepatitis C infection in a renal allograft recipient using tacrolimus. | 2002 | Am. J. Kidney Dis. | pmid:12087579 |
Starzl TE et al. | Tacrolimus (FK506) and the pharmaceutical/academic/regulatory gauntlet. | 1998 | Am. J. Kidney Dis. | pmid:9631858 |
Li X et al. | Tacrolimus therapy in adults with steroid- and cyclophosphamide-resistant nephrotic syndrome and normal or mildly reduced GFR. | 2009 | Am. J. Kidney Dis. | pmid:19406543 |
Al-Awwa IA et al. | Importance of allograft biopsy in renal transplant recipients: correlation between clinical and histological diagnosis. | 1998 | Am. J. Kidney Dis. | pmid:9631859 |
First MR | Renal transplantation for the nephrologist: new immunosuppressive drugs. | 1992 | Am. J. Kidney Dis. | pmid:1371201 |
Israni A et al. | Conversion to tacrolimus for the treatment of cyclosporine-associated nephrotoxicity in heart transplant recipients. | 2002 | Am. J. Kidney Dis. | pmid:11877596 |
Mathis AS and Friedman GS | Coadministration of digoxin with itraconazole in renal transplant recipients. | 2001 | Am. J. Kidney Dis. | pmid:11157404 |
Asif A et al. | Peritoneoscopic placement of peritoneal dialysis catheter and bowel perforation: experience of an interventional nephrology program. | 2003 | Am. J. Kidney Dis. | pmid:14655200 |
Lien YH | Top 10 Things Primary Care Physicians Should Know About Maintenance Immunosuppression for Transplant Recipients. | 2016 | Am. J. Med. | pmid:26714210 |
Bar J et al. | Is immunosuppression therapy in renal allograft recipients teratogenic? A single-center experience. | 2003 | Am. J. Med. Genet. A | pmid:12476448 |
Perez-Aytes A et al. | In utero exposure to mycophenolate mofetil: a characteristic phenotype? | 2008 | Am. J. Med. Genet. A | pmid:18074358 |
Chen W et al. | Outcomes of tacrolimus therapy in adults with refractory membranous nephrotic syndrome: a prospective, multicenter clinical trial. | 2013 | Am. J. Med. Sci. | pmid:22627258 |
Hsu MS et al. | Clinical features and outcome of tuberculosis in solid organ transplant recipients. | 2007 | Am. J. Med. Sci. | pmid:17700199 |
Ocampo-Garza J et al. | Acquired Hyperpigmentation and Cicatricial Alopecia. | 2016 | Am. J. Med. Sci. | pmid:27524226 |
Chen M et al. | Tacrolimus combined with corticosteroids in treatment of nephrotic idiopathic membranous nephropathy: a multicenter randomized controlled trial. | 2010 | Am. J. Med. Sci. | pmid:20220333 |
El-Dahshan KF et al. | Ketoconazole-tacrolimus coadministration in kidney transplant recipients: two-year results of a prospective randomized study. | 2006 | Am. J. Nephrol. | pmid:16804292 |