Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with tacrolimus
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Jungersted JM et al. | Effects of topical corticosteroid and tacrolimus on ceramides and irritancy to sodium lauryl sulphate in healthy skin. | 2011 | Acta Derm. Venereol. | pmid:21365172 |
Quist SR et al. | Effects of Topical Tacrolimus and Polyunsaturated Fatty Acids on In Vivo Release of Eicosanoids in Atopic Dermatitis During Dermal Microdialysis. | 2016 | Acta Derm. Venereol. | pmid:26911315 |
Zattra E et al. | Labial melanotic macule after application of topical tacrolimus: two case reports. | 2010 | Acta Derm. Venereol. | pmid:20814635 |
Bovenschen HJ | Novel treatment for cheilitis glandularis. | 2009 | Acta Derm. Venereol. | pmid:19197557 |
Hartmann A et al. | Treatment of generalised vitiligo with tacrolimus 0.1% ointment vs. UVB intense pulsed light phototherapy: a pilot study. | 2014 | Acta Derm. Venereol. | pmid:24473666 |
Granlund H et al. | Treatment of lichenified atopic eczema with tacrolimus ointment. | 2001 Aug-Sep | Acta Derm. Venereol. | pmid:11720192 |
Pagliarello C and Paradisi A | Topical tacrolimus is useful for avoiding suction-blister epidermal grafting depigmentation in non-segmental vitiligo: a case report. | 2012 | Acta Derm. Venereol. | pmid:22101735 |
Hamade Y et al. | Lichen planus in childhood showing various cutaneous features. | 2012 | Acta Derm. Venereol. | pmid:22101991 |
Mandelin J et al. | Leg ulcers treated with topical tacrolimus in patients with rheumatoid arthritis. | 2010 | Acta Derm. Venereol. | pmid:21057750 |
Nakamizo S et al. | Treatment of neuropathic itch possibly due to trigeminal trophic syndrome with 0.1% topical tacrolimus and gabapentin. | 2010 | Acta Derm. Venereol. | pmid:21057761 |
Mandelin J et al. | One-year treatment with 0.1% tacrolimus ointment versus a corticosteroid regimen in adults with moderate to severe atopic dermatitis: A randomized, double-blind, comparative trial. | 2010 | Acta Derm. Venereol. | pmid:20169301 |
Ujiie H et al. | Successful treatment of nail lichen planus with topical tacrolimus. | 2010 | Acta Derm. Venereol. | pmid:20169322 |
Jensen JM et al. | Effects of pimecrolimus compared with triamcinolone acetonide cream on skin barrier structure in atopic dermatitis: a randomized, double-blind, right-left arm trial. | 2013 | Acta Derm. Venereol. | pmid:23571785 |
Pitarch G et al. | Systemic absorption of topical tacrolimus in Pyoderma gangrenosum. | 2006 | Acta Derm. Venereol. | pmid:16585995 |
Cunha PR | Pimecrolimus cream 1% is effective in seborrhoeic dermatitis refractory to treatment with topical corticosteroids. | 2006 | Acta Derm. Venereol. | pmid:16585998 |
Cunha PR and Rossi AB | Pimecrolimus cream 1% is effective in a case of granulomatous rosacea. | 2006 | Acta Derm. Venereol. | pmid:16585999 |
Chittock J et al. | Comparing the Effect of a Twice-weekly Tacrolimus and Betamethasone Valerate Dose on the Subclinical Epidermal Barrier Defect in Atopic Dermatitis. | 2015 | Acta Derm. Venereol. | pmid:25594610 |
De Rie MA et al. | Soluble interleukin-2 receptor (sIL-2R) is a marker of disease activity in psoriasis: a comparison of sIL-2R, sCD27, sCD4, sCD8 and sICAM-1. | 1996 | Acta Derm. Venereol. | pmid:8891007 |
Pagliarello C et al. | Topical tacrolimus and 50% zinc oxide paste for Hailey-Hailey disease: less is more. | 2012 | Acta Derm. Venereol. | pmid:22293917 |
Kim TW et al. | Proactive treatment of adult facial seborrhoeic dermatitis with 0.1% tacrolimus ointment: randomized, double-blind, vehicle-controlled, multi-centre trial. | 2013 | Acta Derm. Venereol. | pmid:23388687 |