Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with tacrolimus
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Shiratori T et al. | [Immunosuppressive treatment of ulcerative colitis]. | 1999 | Nippon Rinsho | pmid:10572417 |
Burke GW et al. | Microangiopathy in kidney and simultaneous pancreas/kidney recipients treated with tacrolimus: evidence of endothelin and cytokine involvement. | 1999 | Transplantation | pmid:10573073 |
Young AL et al. | Allo-limbal transplantation in patients with limbal stem cell deficiency. | 1999 | Br J Ophthalmol | pmid:10574823 |
Rao SK et al. | Limbal allografting using FK-506. | 1999 | Br J Ophthalmol | pmid:10574824 |
Zhang Y et al. | Immunosuppressant FK506 activates NF-kappaB through the proteasome-mediated degradation of IkappaBalpha. Requirement for Ikappabalpha n-terminal phosphorylation but not ubiquitination sites. | 1999 | J. Biol. Chem. | pmid:10574930 |
Undre NA et al. | Pharmacokinetics of tacrolimus: clinically relevant aspects. | 1999 | Transplant. Proc. | pmid:10576037 |
Mayer AD | Four-year follow-up of the European Tacrolimus Multicenter Renal Study. | 1999 | Transplant. Proc. | pmid:10576038 |
Jordan ML et al. | Tacrolimus-based immunosuppression in pediatric renal transplantation. | 1999 | Transplant. Proc. | pmid:10576039 |
Kliem V et al. | Conversion to tacrolimus for acute corticosteroid- and antibody-resistant rejection following kidney transplantation. | 1999 | Transplant. Proc. | pmid:10576041 |
Friemann S et al. | Conversion to tacrolimus in hyperlipidemic patients. | 1999 | Transplant. Proc. | pmid:10576042 |
Kohnle M et al. | Conversion from cyclosporine to tacrolimus in renal transplant recipients with gum hyperplasia. | 1999 | Transplant. Proc. | pmid:10576043 |
van Hooff JP et al. | Tacrolimus and glucose metabolism. | 1999 | Transplant. Proc. | pmid:10576044 |
Soriano S et al. | Single-center experience with initial intravenous dosing of tacrolimus after kidney transplantation. | 1999 | Transplant. Proc. | pmid:10576045 |
van Hooff JP et al. | Dosing and management guidelines for tacrolimus in renal transplant patients. | 1999 | Transplant. Proc. | pmid:10576046 |
Oliveira DB and Chang R | Report of the first 118 tacrolimus-treated patients at St George's Hospital, London. | 1999 | Transplant. Proc. | pmid:10576047 |
Jurewicz WA | Immunological and nonimmunological risk factors with tacrolimus and Neoral in renal transplant recipients: an interim report. | 1999 | Transplant. Proc. | pmid:10576048 |
Forsythe J | Tacrolimus and mycophenolate mofetil in cadaveric renal transplant recipients. The European Multicentre Tacrolimus/MMF Study Group. | 1999 | Transplant. Proc. | pmid:10576049 |
Squifflet JP et al. | The Benelux experience with the combination of tacrolimus and mycophenolate mofetil. | 1999 | Transplant. Proc. | pmid:10576050 |
Morales JM et al. | Tacrolimus, mycophenolate mofetil and corticosteroids as primary immunosuppression after renal transplantation at the Hospital 12 de Octubre, Madrid. | 1999 | Transplant. Proc. | pmid:10576051 |
Jordan ML et al. | Outcome of tacrolimus conversion therapy for renal allograft rejection: 5-year follow-up. | 1999 | Transplant. Proc. | pmid:10576052 |