Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with tacrolimus
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Hodge S et al. | Postinoculation PMPA treatment, but not preinoculation immunomodulatory therapy, protects against development of acute disease induced by the unique simian immunodeficiency virus SIVsmmPBj. | 1999 | J. Virol. | pmid:10482616 |
Fleischer AB | Treatment of atopic dermatitis: role of tacrolimus ointment as a topical noncorticosteroidal therapy. | 1999 | J. Allergy Clin. Immunol. | pmid:10482864 |
Mookerjee B et al. | Salvage therapy for refractory chronic graft-versus-host disease with mycophenolate mofetil and tacrolimus. | 1999 | Bone Marrow Transplant. | pmid:10482936 |
Otsu S et al. | [T cell non-depleted bone marrow transplantation for primary refractory erythroleukemia using a partially HLA-mismatched related donor]. | 1999 | Rinsho Ketsueki | pmid:10483142 |
Tsuji-Takayama K et al. | Interleukin-18 induces interferon-gamma production through NF-kappaB and NFAT activation in murine T helper type 1 cells. | 1999 | Cell. Immunol. | pmid:10486154 |
Pinna AD et al. | Unusual presentation of graft-versus-host disease in pediatric liver transplant recipients: evidence of late and recurrent disease. | 1999 | Pediatr Transplant | pmid:10487286 |
Muthuswamy SK et al. | Controlled dimerization of ErbB receptors provides evidence for differential signaling by homo- and heterodimers. | 1999 | Mol. Cell. Biol. | pmid:10490623 |
Ahlers C et al. | Cyclosporin A inhibits Ca2+-mediated upregulation of the DNA repair enzyme DNA polymerase beta in human peripheral blood mononuclear cells. | 1999 | Eur. J. Biochem. | pmid:10491144 |
Sata M and Walsh K | Cyclosporine downregulates Fas ligand expression on vascular endothelial cells: implication for accelerated vasculopathy by immunosuppressive therapy. | 1999 | Biochem. Biophys. Res. Commun. | pmid:10491310 |
Yeh CN et al. | Acute overdoses of tacrolimus (FK 506). | 1999 | Dig. Dis. Sci. | pmid:10492148 |